A team of researchers and students at the University of California, Riverside has created a Lego-like system of blocks that enables users to custom build chemical and biological research instruments. The system of 3D-printed blocks can create a variety of scientific tools.
The blocks, which are called Multifluidic Evolutionary Components (MECs) appeared in the journal PLOS ONE. Each block in the system performs a basic lab instrument task (pumping fluids, making measurements or interfacing with a user, for example). Since the blocks are designed to work together, users can build apparatus — like bioreactors for making alternative fuels or acid-base titration tools for high school chemistry classes — rapidly and efficiently. The blocks are especially well suited for resource-limited settings, where a library of blocks can create a variety of different research and diagnostic tools.
Continue reading “Lego-Like Chemistry and Biology Erector Set”
Slit lamps are prohibitively expensive in the third world areas of India where they are most needed. An invention that’s been around for over a hundred years, the slit lamp is a simple-in-concept way to see and diagnose a large array of ocular issues.
Since they are relatively old by technological standards, the principles behind them have become more and more understood as time has gone on. While a nice lab version with a corneal microscope is certainly better, innovations in manufacturing have brought the theoretical minimum cost of the device way down, or at least that’s what [Kewal Chand Swami] hopes.
His design aims for portability and cost reduction. It must be able to travel to remote locations and it must be significantly cheaper than the lab versions. It uses off-the-shelf lenses in a 3D printed housing with a simple LED torch, the kind you can buy for a dollar at the check-out stand.
The assembly slides onto the user’s head and is held there with straps. The doctor can adjust where the slit the lamp shines and also look through a microscope to diagnose the issue. Hopefully devices like this will see similar community support to the prosthetic projects we’ve covered.
[F.Lab] is really worried that we are going to prepare a DNA sample from saliva, dish soap, and rubbing alcohol in their 3D-printed centrifuge and then drink it like a shot. Perhaps they have learned from an horrific experience, perhaps biologists have different dietary requirements. Either way, their centrifuge is really cool. Just don’t drink the result. (Ed note: it’s the rubbing alcohol.)
The centrifuge was designed in Sketch-Up and then 3D printed. They note to take extra care to get high quality 3D prints so that the rotor isn’t out of balance. To get the high speeds needed for the extraction, they use a brushless motor from a quadcopter. This is combined with an Arduino and an ESC. There are full assembly instructions on Thingiverse.
[F.Lab] has some other DIY lab equipment designs, such as this magnetic stirrer. Which we assume you could use to make a shot if you wanted to. However, it’s probably not a good idea to mix lab supplies and food surfaces. Video after the break.
Continue reading “DNA Extraction With A 3D-Printed Centrifuge”
Microchips and integrated circuits are usually treated as black boxes; a signal goes in, and a signal goes out, and everything between those two events can be predicted and accurately modeled from a datasheet. Of course, the reality is much more complex, as any picture of a decapped IC will tell you.
[Jim Conner] got his hands on a set of four ‘teaching’ microchips made by Motorola in 1992 that elucidates the complexities of integrated circuitry perfectly: instead of being clad in opaque epoxy, these chips are encased in transparent plastic.
The four transparent chips are beautiful works of engineering art, with the chip carriers, the bond wires, and the tiny square of silicon all visible to the naked eye. The educational set covers everything from resistors, n-channel and p-channel MOSFETS, diodes, and a ring oscillator circuit.
[Jim] has the chips and the datasheets, but doesn’t have the teaching materials and lab books that also came as a kit. In lieu of proper pedagogical technique, [Jim] ended up doing what any of us would: looking at it with a microscope and poking it with a multimeter and oscilloscope.
While the video below only goes over the first chip packed full of resistors, there are some interesting tidbits. One of the last experiments for this chip includes a hall effect sensor, in this case just a large, square resistor with multiple contacts around the perimeter. When a magnetic field is applied, some of the electrons are deflected, and with a careful experimental setup this magnetic field can be detected on an oscilloscope.
[Jim]’s video is a wonderful introduction to the black box of integrated circuits, but the existence of clear ICs leaves us wondering why these aren’t being made now. It’s too much to ask for Motorola to do a new run of these extremely educational chips, but why these chips are relegated to a closet in an engineering lab or the rare eBay auction is anyone’s guess.
16A lot of engineers, scientists, builders, makers, and hackers got their start as children with LEGO. Putting those bricks together, whether following the instructions or not, really brings out the imagination. It’s not surprising that some people grow up and still use LEGO in their projects, like [Steve] who has used LEGO to build an optics lab with a laser beam splitter.
[Steve] started this project by salvaging parts from a broken computer projector. Some of the parts were scorched beyond repair, but he did find some lenses and mirrors and a mystery glass cube. It turns out that this cube is a dichroic prism which is used for combining images from the different LCD screens in the projector, but with the right LEGO bricks it can also be used for splitting a laser beam.
The cube was set on a LEGO rotating piece to demonstrate how it can split the laser at certain angles. LEGO purists might be upset at the Erector set that was snuck into this project, but this was necessary to hold up the laser pointer. This is a great use of these building blocks though, and [Steve] finally has his optics lab that he’s wanted to build for a while. If that doesn’t scratch your LEGO itch, we’ve also featured this LEGO lab which was built to measure the Planck constant.
Biohackers, fire up your laser cutters. [CopabX] has developed OpenFuge: a (relatively) low-cost, open-source centrifuge from powerful hobby electronic components. If you thought the VCR centrifuge wasn’t impressive, trolls be damned— OpenFuge can crank out 9000 RPM and claims it’s capable of an impressive 6000 G’s. [CopabX] also worked in adjustable speed and power, setting time durations, and an LCD to display live RPM and countdown stats.
And it’s portable. Four 18650 lithium cells plug into the back, making this centrifuge a truly unique little build. The muscle comes from a DC outrunner brushless motor similar to the ones that can blast you around on a skateboard but with one key difference; an emphasis on RPMs over torque. We’re not sure exactly which motor is pictured, but one suggestion on the bill of materials boasts a 6000 KV rating, and despite inevitable losses, that’s blazing fast at nearly 15V.
You’ll want to see the demonstration video after the break, but also make time to swing by Thingiverse for schematics and recommended parts.
Continue reading “OpenFuge: an open-source centrifuge”
VCR’s practically scream “tear me open!” with all those shiny, moving parts and a minimal risk that you’re going to damage a piece of equipment that someone actually cares about. Once you’ve broken in, why not hack it into a centrifuge like [Kymyst]? Separating water from the denser stuff doesn’t require lab-grade equipment. As [Kymyst] explains: you can get a force of 10 G just spinning something around your head. By harvesting some belt drives from a few VCR’s, however, he built this safer, arm-preserving motor-driven device.
[Kymst] dissected the video head rotor and cassette motor drive down to a bare minimum of parts which were reassembled in a stack. A bored-out old CD was attached beneath the rotor while a large plastic bowl was bolted onto the CD. The bowl–here a microwave cooking cover–acts as a protective barrier against the tubes spinning inside. The tube carriers consist of plastic irrigation tubing fitted with a homemade trunnion, which [Kymyst] fashioned from some self-tapping screws and a piece of PVC. At 250 rpm, this centrifuge reaches around 6 G and best of all, gives a VCR something to do again. Take a look at his guide and make your own, particularly if your hackerspace has a bio lab.