Microfluidics “Frogger” is a Game Changer for DIY Biology

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See those blue and green dots in the GIF? Those aren’t pixels on an LCD display. Those are actual drops of liquid moving across a special PCB. The fact that the droplets are being manipulated to play a microfluidics game of “Frogger” only makes OpenDrop v 2.0 even cooler.

Lab biology is mainly an exercise in liquid handling – transferring a little of solution X into some of solution Y with a pipette. Manual pipetting is tedious, error prone, and very low throughput, but automated liquid handling workstations run into the hundreds of thousands of dollars. This makes [Urs Gaudenz]’s “OpenDrop” microfluidics project a potential game changer for the nascent biohacking movement by offering cheap and easy desktop liquid handling.

Details are scarce on the OpenDrop website as to exactly how this works, but diving into the literature cited reveals that the pads on the PCB are driven to high voltages to attract the droplets. The PCB itself is covered with a hydrophobic film – Saran wrap that has been treated with either peanut oil or Rain-X. Moving the droplets is a simple matter of controlling which pads are charged. Splitting drops is possible, as is combining them – witness the “frog” getting run over by the blue car.

There is a lot of cool work being done in microfluidics, and we’re looking forward to see what comes out of this open effort. We’ve covered other open source efforts in microfluidics before, but this one seems so approachable that it’s sure to capture someone’s imagination.

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Hacked Diamond Makes Two-Atom Radio

It used to be pretty keen to stuff a radio receiver into an Altoid’s tin, or to whip up a tiny crystal receiver from a razor blade and a pencil stub. But Harvard researchers have far surpassed those achievements in miniaturization with a nano-scale FM receiver built from a hacked diamond.

As with all such research, the experiments in [Marko Lončar]’s lab are nowhere near as simple as the press release makes things sound. While it’s true that a two-atom cell is the minimal BOM for a detector, the device heard belting out a seasonal favorite from [Andy Williams] in the video below uses billions of nitrogen-vacancy (N-V) centers. N-V centers replace carbon atoms in the diamond crystal with nitrogen atoms; this causes a “vacancy” in the crystal lattice and lends photoluminescent properties to the diamond that are sensitive to microwaves. When pumped by a green laser, incident FM radio waves in the 2.8 GHz range are transduced into AM fluorescent signals that can be detected with a photodiode and amplifier.

The full paper has all the details, shows that the radio can survive extreme pressure and temperature regimes, and describes potential applications for the system. It’s far from a home-gamer’s hack at this point, but it’s a neat trick and one to watch for future exploitation. In the meantime, here’s an accidental FM radio with a pretty small footprint.

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Mexican Highschoolers Launch 30 High Altitude Balloons

No matter whether you call them “picosatellites” or “high altitude balloons” or “spaceblimps”, launching your own electronics package into the air, collecting some high-altitude photos and data, and then picking the thing back up is a lot of fun. It’s also educational and inspirational. We’re guessing that 264 students from 30 high schools in Aguascalientes Mexico have new background screens on their laptops today thanks to the CatSat program (translated here by robots, and there’s also a video to check out below).

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Fripon is French for Meteorite Hunting

Just a few weeks ago, we reported on a US NASA project to track the path and estimate the size of meteoroids in the sky using a distributed network of a handful of cameras. It turns out that there’s a similar French effort, and it’s even cooler: the Fireball Recovery and InterPlanetary Observation Network (FRIPON). (The name is cute, if the acronym is contrived: a “fripon” is a trickster in French.)

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Drone Vs. Airplane? Who Will Win? Science Knows.

Ignore the article, watch the video at the top of the page. The article is about some idiot, likely not even a hacker, who bought a drone somewhere and nearly rammed it into a plane. He managed this with concentrated idiocy, intention was not involved. While these idiots are working hard to get our cool toys taken away, researchers elsewhere are answering the question of exactly how much threat a drone poses to an airplane.

droneexplode_thumbAirplanes are apparently armored to withstand a strike from an 8lb bird. However, even if in a similar weight class, a drone is not constructed of the same stuff. To understand if this mattered, step one was to exactly model a DJI Phantom and then digitally launch it at various sections of a very expensive airplane.

The next step, apparently, was to put a drone into an air cannon and launch it at an aluminum sheet. The drone explodes quite dramatically. Some people have the best jobs.

The study is still ongoing, but from the little clips seen; the drone loses. Along with the rest of us.

Perhaps the larger problem to think about right now is how to establish if a “drone” has actually been involved in an incident with a passenger aircraft. It seems there are a lot of instances where that claim is dubious.

Physics or Phiction?

Do you remember Gilligan’s Island? For many people of a certain age, “The Professor” was our first impression of what a scientist was like. Even in those simpler times, though, you probably couldn’t find anyone like the professor; a jack of all trades, he sort of knew everything about everything (except, apparently, how to make a boat).

Real scientists tend to hyper-specialize. Getting grant money, publication pages, and just advancing the state of the art means that you get more and more focused on more obscure things. It is getting to the point that two scientists in the same field may not be able to really understand each other. You see the same thing in engineering to some degree. Not many digital designers can talk about the frequency dependence of Early effect in bipolar transistors, but not many device gurus can talk intelligently about reservation techniques for superscalar CPUs.

There’s now a website that lets you guess if a physics paper title is real or if it made up jibberish. The site, snarXiv, gets the real titles from arXiv, the site that contains many preprint papers. For example, we were asked to guess if “Brane Worlds with Bolts” was a real paper or if it was “Anthropic Approaches to the Flavor Problem.” (For the record, it was the one about branes.) Give it a whirl!

Testing the Speed-of-Light Conspiracy

There are a number of ways to measure the speed of light. If you’ve got an oscilloscope and a few spare parts, you can build your own apparatus for just a few bucks. Don’t believe the “lies” that “they” tell you: measure it yourself!

OK, we’re pretty sure that conspiracy theories weren’t the motivation that got [Michael Gallant] to build his own speed-of-light measurement rig, but the result is a great writeup, and a project that includes one of our favorite circuits, the avalanche transistor pulse generator.

setupThe apparatus starts off with a very quickly pulsed IR LED, a lens, and a beam-splitter. One half of the beam takes a shortcut, and the other bounces off a mirror that is farther away. A simple op-amp circuit amplifies the resulting pulses after they are detected by a photodiode. The delay is measured on an oscilloscope, and the path difference measured with a tape measure.

If you happen to have a photomultiplier tube in your junk box, you can do away with the amplifier stage. Or if you have some really fast logic circuits, here’s another project that might interest you. But if you just want the most direct measurement we can think of that’s astoundingly accurate for something lashed up on breadboards, you can’t beat [Michael]’s lash-up.

Oh and PS: He got 299,000 (+/- 5,000) km/sec.