[Dr. Iguana's] experience moving from projects powered by disposable Alkaline cells and linear regulators to recycled Lithium Ion cells using the buck regulators seen above might serve as an inspiration to make the transition in your own projects.
The recycled cells he’s talking about are pulled out of larger battery packs. As we’ve seen in the past, dead battery packs for rechargeable tools, laptops, etc., are often plagued by a few bad apples. A small number of dead cells can bork the entire battery even though many perfectly usable cells remain. Once he decided to make the switch it was time to consider power regulation. He first looked at whether to use the cells in parallel or series. Parallel are easier to charge, but boosting the voltage to the desired level ends up costing more. He decided to go with cells in series, which can be regulated with the a less expensive buck converter. In this case he made a board for the RT8289 chip. The drawback of this method requires that you monitor each cell individually during charging to ensure you don’t have the same problem that killed the battery from which you pulled these good cells.