Flock of Butterflies has just published their third post in a series about the ArduiNIX, an Arduino shield that drives Nixie tubes.We’ve featured Nixie tube projects such as a single tube clock, free-formed Nixie circuits, and tubes in a bottle. Now the hurdle of handling high voltage tubes while protecting low voltage logic circuitry has been taken care of for you. The shield can be purchased as a kit but the Eagle CAD files are also available, allowing you to etch your own circuit board.
Although this is meant for the Arduino there is nothing to keep you from using it as a driver with any microcontroller. The board listens for 5V logic levels to switch the multiplexed display of up to eight tubes. Get your hands on some Nixies and give this a try yourself.