Noninvasive Sensors For Brain–Machine Interfaces Based On Micropatterned Epitaxial Graphene

As fun as brain-computer interfaces (BCI) are, for the best results they tend to come with the major asterisk of requiring the cutting and lifting of a section of the skull in order to implant a Utah array or similar electrode system. A non-invasive alternative consists out of electrodes which are placed on the skin, yet at a reduced resolution. These electrodes are the subject of a recent experiment by [Shaikh Nayeem Faisal] and colleagues in ACS Applied NanoMaterials employing graphene-coated electrodes in an attempt to optimize their performance.

Impedance values of eight-channel FEG and eight-channel HPEG sensor systems placed on the occipital area of the head. (Faisal et al., 2023)
Impedance values of eight-channel FEG and eight-channel HPEG sensor systems placed on the occipital area of the head. (Faisal et al., 2023)

Although external electrodes can be acceptable for basic tasks, such as registering a response to a specific (visual) impulse or for EEG recordings, they can be impractical in general use. Much of this is due to the disadvantages of the ‘wet’ and ‘dry’ varieties, which as the name suggests involve an electrically conductive gel with the former.

This gel ensures solid contact and a resistance of no more than 5 – 30 kΩ at 50 Hz, whereas dry sensors perform rather poorly at >200 kΩ at 50 Hz with worse signal-to-noise characteristics, even before adding in issues such as using the sensor on a hairy scalp, as tends to be the case for most human subjects.

In this study, they created electrode arrays in a number of configurations, each of which used graphene as the interface material. The goal was to get a signal even through human hair — such as on the back of the head near the visual cortex — that would be on-par with wet electrodes. The researchers got very promising results with hex-patterned epitaxial graphene (HEPG) sensors, and even in this early prototype stage, the technique could offer an alternative where wet electrodes are not an option.

While the subject is complex, brain-computer interfaces don’t have to be the sole domain of research laboratories. We recently covered an open hardware Raspberry Pi add-on that can let you experiment with detecting and filtering biosignals from the comfort of your own home.

4 thoughts on “Noninvasive Sensors For Brain–Machine Interfaces Based On Micropatterned Epitaxial Graphene

  1. “requiring the cutting and lifting of a section of the skull in order to implant a Utah array” ….. last time I tried this I was overcome with an almost irresistible urge to have a taste. Apparently, according to Bard, it tastes like foie gras.

  2. The problem with external arrays are that the brain is not fixed in place relative to the skull, as you tilt your head the brain moves a few millimetres, and
    How do you focus on anything deeper in the brain than the neocortex?

    This would need a high density array 1 sensor / mm and positional awareness of the current location of the brain in the skull

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