Big Chemistry: From Gasoline To Wintergreen

Most of us probably have some vivid memories of high school or college chemistry lab, where the principles of the science were demonstrated, and where we all got at least a little practice in experimental methods. Measuring, diluting, precipitating, titrating, all generally conducted under safe conditions using stuff that wasn’t likely to blow up or burn.

But dropwise additions and reaction volumes measured in milliliters are not the stuff upon which to build a global economy that feeds, clothes, and provides for eight billion people. For chemistry to go beyond the lab, it needs to be scaled up, often to a point that’s hard to conceptualize. Big chemistry and big engineering go hand in hand, delivering processes that transform the simplest, most abundant substances into the things that, for better or worse, make life possible.

To get a better idea of how big chemistry does that, we’re going to take a look at one simple molecule that we’ve probably all used at one time or another: the common artificial flavoring wintergreen. It’s an innocuous ingredient in a wide range of foods and medicines, but the infrastructure required to make it and all its precursors is a snapshot of just how important big chemistry really is.

Continue reading “Big Chemistry: From Gasoline To Wintergreen”

Haber-Bosch And The Greening Of Ammonia Production

We here on Earth live at the bottom of an ocean of nitrogen. Nearly 80% of every breath we take is nitrogen, and the element is a vital component of the building blocks of life. Nitrogen is critical to the backbone of proteins that form the scaffold that life hangs on and that catalyze the myriad reactions in our cells, and the information needed to build these biopolymers is encoded in nucleic acids, themselves nitrogen-rich molecules.

And yet, in its abundant gaseous form, nitrogen remains directly unavailable to higher life forms, unusably inert and unreactive. We must steal our vital supply of nitrogen from the few species that have learned the biochemical trick of turning atmospheric nitrogen into more reactive compounds like ammonia. Or at least until relatively recently, when a couple of particularly clever members of our species found a way to pull nitrogen from the air using a combination of chemistry and engineering now known as the Haber-Bosch process.

Haber-Bosch has been wildly successful, and thanks to the crops fertilized with its nitrogenous output, is directly responsible for growing the population from a billion people in 1900 to almost eight billion people today. Fully 50% of the nitrogen in your body right now probably came from a Haber-Bosch reactor somewhere, so we all quite literally depend on it for our lives. As miraculous as Haber-Bosch is, though, it’s not without its problems, particularly in this age of dwindling supplies of the fossil fuels needed to run it. Here, we’ll take a deep dive into Haber-Bosch, and we’ll also take a look at ways to potentially decarbonize our nitrogen fixation industry in the future.

Continue reading “Haber-Bosch And The Greening Of Ammonia Production”