Lab Gloves May Be Skewing Microplastics Data

The topic of micro- and nanoplastics (MNPs) has become increasingly prevalent over the past years, as amidst dismissal and panic, researchers attempt to distinguish just how much of a problem MNPs truly are. The most essential problem here is that we are still developing the tools to accurately measure the levels of MNP contamination. Recently, [Madeline E. Clough] et al. demonstrated in an article published in Analytical Methods how gloves worn in laboratory settings can create false positive MNP signals.

As we covered previously, detecting MNPs is tough due to the detection methods used, many of which rely on interpreting signals from methods like pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS), with protocols for this and other methods still being worked on, particularly on how to filter out false positives.

The article by [Clough] demonstrates how dry contact of lab gloves on samples can deposit stearate salts – left over from their production, which are subsequently misidentified as being MNPs, specifically polyethylene (PE). These false positives occur with µ-Fourier transform infrared (µ-FTIR) spectroscopy and µ-Raman spectroscopy, but can occur with Py-GC-MS as well, as has been determined previously. Substances like the fatty lipids that are commonly found in the human body, and in particular the brain, will closely match the PE signature.

With these very common stearate salts now also a likely source of contamination with MNP measurements, it just becomes more obvious that it’s incredibly hard to make accurate assessments about any hazards of MNPs until we can determine their presence with any level of reliability.

13 thoughts on “Lab Gloves May Be Skewing Microplastics Data

    1. I think one look at the amount of plastic waste humanity produces should tell you that we definitely have a problem, whether or not the results of this particular test are off.

  1. I wonder about false positives in other research as well.

    There was a pollution sensor located right next to a school’s bus fleet area….like putting a thermostat inside a heater itself -DUMB!

    1. Um, what? Is the pollution sensor measuring the overall produced pollution, or just what remains in a specific area, or ? If you want to measure the pollution of the area around where schoolchildren are exposed, why yes, I can’t argue. But they may be trying to measure pollution PRODUCED, whether it’s floating straight into the atmosphere above or blown into the wind; in which case the school’s bus fleet area is perfect.
      Do they get funding dependent on the results? maybe there’s cheating, but if my kid were attending a school near that parking area, I’d like for a heavy thumb on the scale, so to speak! Maybe this is a property not actually near a school, but a fleet area quite separate from nearby schools, residences or offices? Sorry to nitpick, but not giving context is a hallmark in the effort to combat global warming acceptance, often done by non-scientist (and a scary number of engineers) to bring into doubt statistics that climate scientist are universally agreed upon. If all you have is a hammer, everything looks like a nail. When I was in school, leaded gasoline was the norm, and I wish someone had tried measuring this exhaust poison, maybe the extra IQ would help me understand what you are trying to discuss

    1. So many studies are done by students, then the media gets them before they’re even peer reviewed; then everybody “knows”; then it takes a decade to unlearn the supposed “facts”.

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