Brain on a chip setup with a hand and a dropper

Gray Matter On A Chip: Building An Artificial Brain With Luminol

Ever wondered if you could build a robot controlled by chemical reactions? [Marb] explores this wild concept in his video, merging chemistry and robotics in a way that feels straight out of sci-fi. From glowing luminol reactions to creating artificial logic gates, [Marb]—a self-proclaimed tinkerer—takes us step-by-step through crafting the building blocks for what might be the simplest form of a chemical brain.

In this video, the possibilities of an artificial chemical brain take centre stage. It starts with chemical reactions, including a fascinating luminol-based clock reaction that acts as a timer. Then, a bionic robot hand makes its debut, complete with a customised interface bridging the chemical and robotic worlds. The highlight? Watching that robotic hand respond to chemical reactions!

The project relies on a “lab-on-a-chip” approach, where microfluidics streamline the processes. Luminol isn’t just for forensic TV shows anymore—it’s the star of this experiment, with resources like this detailed explanation breaking down the chemistry. For further reading, New Scientist has you covered.

We’ve had interesting articles on mapping the human brain before, one on how exactly brains might work, or even the design of a tiny robot brain. Food for thought, or in other words: stirring the gray matter.

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Making Luminol From Household Chemicals

What to make your own chemiluminescent material? Check out this process that uses common household goods to synthesize luminol. You’ll need some lab equipment, and [NurdRage] mentions some precautions to take as luminol is not itself toxic, but some of the fumes and intermediary chemicals found during the process are.

Start by cutting up some vinyl gloves and boiling them with some rubbing alcohol to extract diethyl hexyl phthalate. After filtering, that gets boiled with water and some drain cleaner. The goal here is to continue the process until you have pure phthalic anhydride. Almost done? Not even getting started. This is a very complicated process, but fascinating to watch. After the break you’ll find the full video, or a five-minute abridged version for those that just want a taste of this experiment.

When we looked at the quantum dot manufacturing process a couple of days ago we asked for more chemistry hacks. This is exactly what we were talking about and are thankful that [Rob] sent in the tip. Keep them coming!

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