[SeanHodgins] has a project in mind where he needs to sample over 500 analog sensors. To get ready, he made a breakout board for 32-channel analog multiplexer device he wants to use. He put the project out on Hackaday.io and also has a video tutorial you can see below.
There are five input pins to the chip which lets you connect one analog pin to any one of 32 analog pins. Of course, in addition to the five control lines, you need some handshaking lines, too so you could use as many as eight digital pins to control the device.