Tetrodotoxin (TTX) is best known as the neurotoxin of the puffer fish, though it also appears in a range of other marine species. You might remember it from an episode of The Simpsons involving a poorly prepared dish at a sushi restaurant. Indeed, it’s a potent thing, as ingesting even tiny amounts can lead to death in short order.

Given its fatal reputation, it might be the last thing you’d expect to be used in a therapeutic context. And yet, tetrodotoxin is proving potentially valuable as a treatment option for dealing with cancer-related pain. It’s a dangerous thing to play with, but it could yet hold promise where other pain relievers simply can’t deliver. Continue reading “Pufferfish Venom Can Kill, Or It Can Relieve Pain” →