How Tattoos Interact With The Immune System Could Have Impacts For Vaccines

Tattoos are an interesting technology. They’re a way of marking patterns and designs on the skin that can last for years or decades. All this, despite the fact that our skin sloughs off on a regular basis!

As it turns out, tattoos actually have a deep and complex interaction with our immune system, which hold some of the secrets regarding their longevity. New research has unveiled more insight into how the body responds when we get inked up.

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Classic Film Camera Goes Digital With Game Boy Tech

Despite having been technologically obsolete for a decade or two, analog photography is still practiced by hobbyists and artists to achieve a particular aesthetic. One might imagine a similar thing happening with early digital cameras, and indeed it has: the Game Boy Camera has seen use in dozens of projects. [Michael Fitzmayer] however decided to combine the worlds of analog and early digital photography by equipping a Holga with the image sensor from a Game Boy Camera.

A camera module and an STM32 module on a solderless breadboardThe Holga, if you’re not familiar, is a cheap film camera from the 1980s that has achieved something of a cult following among retro-photography enthusiasts. By equipping it with the sensor from what was one of the first mass-market digital cameras, [Michael] has created a rather unusual digital point-and-shoot. The user interface is as simple as can be: a single button to take a photo, and nothing else. There’s no screen to check your work — just as with film, you’ll have to wait for the pictures to come back from the lab.

The sensor used in the Game Boy Camera is a Mitsubishi M64282FP, which is a 128 x 128 pixel monochrome CMOS unit. [Michael] hooked it up to an STM32F401 microcontroller, which reads out the sensor data and stores it on an SD card in the form of a bitmap image.

With no film roll present, the Holga has plenty of space for all the electronics and a battery. The original lens turned out to be a poor fit for the image sensor, but with a bit of tweaking the Game Boy optics fit in its place without significantly altering the camera’s appearance.

A monochrome low-resolution selfie of a man making the peace sign[Michael] helpfully documented the design process and shared all source code on his GitHub page. Holgas shouldn’t be hard to find to find, but if none are available in your area you can just roll your own. The Game Boy Camera is actually one of the most versatile cameras out there, having been used for everything from video conferencing to astrophotography.

A NOR Gate For An ALU?

If you know anything about he design of a CPU, you’ll probably be able to identify that a critical component of all CPUs is the Arithmetic Logic Unit, or ALU. This is a collection of gates that can do a selection of binary operations, and which depending on the capabilities of the computer, can be a complex component. It’s a surprise then to find that a working CPU can be made with just a single NOR gate — which is what is at the heart of [Dennis Kuschel]’s My4th single board discrete logic computer. It’s the latest in a series of machines from him using the NOR ALU technique, and it replaces hardware complexity with extra software to perform complex operations.

Aside from a refreshingly simple and understandable circuit, it has 32k of RAM and a 32k EPROM, of which about 9k is microcode and the rest program. It’s called My4th because it has a Forth interpreter on board, and it has I2C and digital I/O as well as a serial port for its console.

This will never be a fast computer, but the fact that it computes at all is ts charm. In 2023 there are very few machines about that can be understood in their entirety, so this one is rather special even if it’s not the first 1-bit ALU we’ve seen.

Thanks [Ken Boak] for the tip.