Your Hackerspace Needs A Biology Lab; Here’s The Inspiration

biology-hackerspace

When you think of Hackerspaces what pops to mind? For us it’s electronics first, then machining related stuff (3D printing, CNC milling), followed by welding, woodworking, auto mechanical, we could go on and on. But biology hacking doesn’t really make that list. The New York based Genspace is a strong case on why we should add a biology lab as a viable hackerspace option.

What are Hackerspaces other than a collection of tools and skilled members that helps to bring the mad scientists of the world out of their basements and into the light? Pretty much every Hackerspace teaches classes that are open to the public. This is basically a requirement of being a non-profit, but is also driven by the virtue of making knowledge open and available. Offering biology themed classes is an incredible tie-in for helping to see our young learners through to a career in the sciences.

Vice-President and Co-Founder [Daniel Grushkin] was inspired by college students who hack organisms for a one semester long project. He wanted to try his hand at it, but needed help with the resources. He gathered a few others who were interested and, with encouragement from NYC Resistor, they got Genspace up and running in Brooklyn. The organization holds safety as a top priority. Each new member learns about the Biosafety Level 1 guidelines used by the space. For less involved experiments they even use tools of their own making, like a glovebox similar to this one.

 

Genetic Testing With Lego

From the dark recesses of the Internet circa 2009 comes the BioBrick-A-Bot, a liquid handling system for molecular biologists.

The 2009 iGEM competition was a student competition to build devices for synthetic biology. The BioBrick-A-Bot’s goal is to build a simple, low-cost liquid handling system that sucks liquids out of petri dishes and into vials.

Like most lab equipment, the commercial version of this tech is insanely expensive – about 10 grand for a commercial liquid handling robot. The BioBrick-A-Bot is made nearly entirely out of LEGO parts, so the cost of the entire system was brought down to about $700.

There are two main parts to the BioBrick-A-Bot. The Alpha module holds four pipette on a delta platform We’ve seen this type of robot built out of LEGO before, but moving liquids is new territory. The Phi module contains all the mechanics to suck microliters of liquid into a pipette and spit them out into vials.

The BioBrick-A-Bot didn’t win the 2009 iGEM competition (that honor was taken by students from Heidelberg Cambridge), but we’d take a LEGO robot any day of the week. Check out the demo after the break.

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Build A Lifeform For Io9


Whether you consider yourself a bona fide mad scientist or you simply think your horrifying mutant creations are misunderstood, you’ll want to enter io9’s Build a Lifeform contest.

The contest doesn’t require any actual primordial soup, just a concept of a synthetic lifeform you think would be useful or interesting. There are two categories with different prizes for each one. The first category asks contestants to use the BioBricks registry of standard biological parts to design a lifeform that could be created in a lab. Descriptions of how it would be made, what it would do, and potential hazards in creating it must all be included with the entry. The winner of this category will recieve an all-expenses-paid trip to the Synthetic Biology Conference in Hong Kong in October.

The second category is more focused on creativity, asking for the same descriptions as the first category without any BioBricks data. While this is the more speculative category, proposed lifeforms must still be plausible to create using current technology. The prize is $1000 and a signed drawing of your lifeform rendered by “a cool comic book artist.”

Both categories offer pretty good loot for your concepts, just be sure they’re more original than an esquilax if you intend to win.

For the background on BioBricks, check out [Drew Endy]’s Hacking DNA talk from last year. He’s one of the judges for the contest.