While spider silk proteins are something you can make in your garage, making useful drag line fibers has proved a daunting challenge. Now, a team of scientists from Japan and Hong Kong are closer to replicating artificial spider silk using microfluidics.
Based on how spiders spin their silk, the researchers designed a microfluidic device to replicate the chemical and physical gradients present in the spider. By varying the amount of shear and chemical triggers, they tuned the nanostructure of the fiber to recreate the “hierarchical nanoscale substructure, which is the hallmark of native silk self-assembly.”
We have to admit, keeping a small bank of these clear, rectangular devices on our desk seems like a lot less work than keeping an army of spiders fed and entertained to produce spider silk Hackaday swag. We shouldn’t expect to see a desktop microfluidic spider silk machine this year, but we’re getting closer and closer. While you wait, why not learn from spiders how to make better 3D prints?
If you’re interesting in making your own spider silk proteins, checkout how [Justin Atkin] and [The Thought Emporium] have done it with yeast. Want to make your spider farm spiders have stronger silk? Try augmenting it with carbon.
Companies spend thousands developing a project for the market, hoping their investment will return big. Investing like this happens every day and won’t shock anyone. What may surprise you is someone who spends more than a decade and thousands of their own dollars to make an open-source version of a highly-marketable product. In this case, we’re talking about genetically modified yeast that produces spider silk. If that sounds like a lead-in to some Spiderman jokes and sci-fi references, you are correct on both accounts. [Justin Atkin] had some geneticist work under his belt when he started, so he planned to follow familiar procedures like extracting black widow DNA, isolating and copying the silk genes, and pasting them into a yeast strain. Easy peasy, right? Naturally, good science doesn’t happen overnight.
There are a few contenders for the strongest spider silk among which the golden silk orb-weaver gets the most attention, but the black widow’s webbing is nearly as strong, and [Justin] is happy to wear black widow inspired bling, whereas the golden orb-weaver looks like it crawled out of Starship Troopers. His first attempt to extract DNA starts with a vial of preserved
nightmare fuel spider specimens because that is a thing you can just go online and buy. Sadly, they were candied in alcohol, and that obliterates DNA, so he moved to dried specimens from breeders, which also failed to produce results, and those were just the landmark hangups.
Continue reading “Spider Silk, Spider Silk, Made Using A Strain Of Yeast”