LEDs are a wonderful technology. You put in a little bit of power, and you get out a wonderful amount of light. They’re efficient, cheap, and plentiful. We use them for so much!
What you might not have known is that these humble components have a secret feature, one largely undocumented in the datasheets. You can use an LED as a light source, sure, but did you know you can use one as a sensor?
[Hugh] has been going back through episodes of the Hackaday podcast, and Elliot mentioned in episode 67 that it can often be inspiring to go back through the archives of Hackaday to find ideas for new projects. Well, he did just that and came across a single-pixel camera made using an infrared photodiode. He decided to try and hack together his own single-pixel camera, but this time on the cheap and using an ever simpler component – a photoresistor!
His description of the project tickled me – “I’ve used an ESP32, MicroPython, two servos, a peanut butter jar lid, a toilet paper roll, a paper towel roll, magnets and scrap wood for this version.” That’s certainly a much simpler bill of materials than the original (which was written up by Hackaday way back in 2015), which used a nice metal frame to hold everything together. However, there’s absolutely nothing wrong with improvising with things you happen to have to hand.
Implantable electrodes for the (human) brain have been around for a many decades in the form of Utah arrays and kin, but these tend to be made out of metal, which can cause issues when stimulating the surrounding neurons with an induced current. This is due to faradaic processes between the metal probe and an electrolyte (i.e. the cerebrospinal fluid). Over time this can result in insulating deposits forming on the probe’s surface, reducing their effectiveness.
Now a company called InBrain claims to have cracked making electrodes out of graphene, following a series of tests on non-human test subjects. Unlike metal probes, these carbon-based probes should be significantly more biocompatible even when used for brain stimulation as with the target goal of treating the symptoms associated with Alzheimer’s.
During the upcoming first phase human subjects would have these implants installed where they would monitor brain activity in Alzheimer’s patients, to gauge how well their medication is helping with the symptoms like tremors. Later these devices would provide deep-brain stimulation, purportedly more efficiently than similar therapies in use today. The FDA was impressed enough at least to give it the ‘breakthrough device’ designation, though it is hard to wade through the marketing hype to get a clear picture of the technology in question.
In their most recently published paper (preprint) in Nature Nanotechnology, [Calia] and colleagues describe flexible graphene depth neural probes (gDNP) which appear to be what is being talked about. These gDNP are used in the experiment to simultaneously record infraslow (<0.1 Hz) and higher frequencies, a feat which metal microelectrodes are claimed to struggle with.
Although few details are available right now, we welcome any brain microelectrode array improvements, as they are incredibly important for many types of medical therapies and research.