neurology

3 Articles

A clear flexible PCB with a number of gold electrodes on one end. It is wrapped over a black cable to demonstrate its flexibility. A set of dashed white lines goes from one end to a zoomed in image of the circuit structure inset in the top right of the image.

Biohybrid Implant Patches Broken Nerves With Stem Cells

March 29, 2023 by 17 Comments

Neural interfaces have made great strides in recent years, but still suffer from poor longevity and resolution. Researchers at the University of Cambridge have developed a biohybrid implant to improve the situation.

As we’ve seen before, interfacing electronics and biological systems is no simple feat. Bodies tend to reject foreign objects, and transplanted nerves can have difficulty assuming new roles. By combining flexible electronics and induced pluripotent stem cells into a single device, the researchers were able to develop a high resolution neural interface that can selectively bind to different neuron types which may allow for better separation of sensation and motor signals in future prostheses.

As is typically the case with new research, the only patients to benefit so far are rats and only on the timescale of the study (28 days). That said, this is a promising step forward for regenerative neurology.

We’re no strangers to bioengineering here. Checkout how you can heal faster with electronic bandages or build a DIY vibrotactile stimulator for Coordinated Reset Stimulation (CRS).

(via Interesting Engineering)

DIY Neuroscience Hack Chat

February 22, 2021 by 8 Comments

Join us on Wednesday, February 24 at noon Pacific for the DIY Neuroscience Hack Chat with Timothy Marzullo!

Watch a film about a mad scientist from the golden age of Hollywood and chances are good that among the other set pieces, you’ll see human brains floating in jars of cloudy fluid wired up to electrodes and fancy machines. It’s all made up, of course, but tropes work because they’re based on a kernel of truth, and we in the audience know that our brains and the other parts of our nervous system do indeed work on electricity. Or more precisely, excitable tissues in our nervous systems pass electrochemical signals between themselves as waves of potential across cell membranes.

Studying this electrical world locked away inside our heads is a challenging, but by no means impossible, pursuit. Usable signals can be picked up, amplified, digitized, and recorded to help us understand what’s going on when we think, feel, move, sleep, wake, or just be. Neuroscience has made tremendous strides looking at these signals, but the equipment to do so has largely remained the province of large universities and teaching hospitals with ample budgets, leaving the amateur neuroscientist out of luck.

Tim Marzullo, co-founder of Backyard Brains, is looking to change all that. While working on his Ph.D. in neuroscience at the University of Michigan, he and Greg Gage looked for ways to make the tools of neuroscience research affordable to everyone. The result is the Neuron SpikerBox, a low-cost bioamplifier that can tap into the “spikes” of action potential in live neurons. Open-source tools like these have helped educators bring neuroscience experiments to STEM students, and even helped other scientists set up novel, low-cost experiments.

Tim will join us on the Hack Chat to talk about doing DIY neuroscience and designing the instruments that make it possible. Bring your “mad scientist” questions as we push back the veil of ignorance on how our brains work, one neuron at a time.

join-hack-chatOur Hack Chats are live community events in the Hackaday.io Hack Chat group messaging. This week we’ll be sitting down on Wednesday, February 24 at 12:00 PM Pacific time (UTC-8). If time zones have you tied up, we have a handy time zone converter.

Click that speech bubble to the right, and you’ll be taken directly to the Hack Chat group on Hackaday.io. You don’t have to wait until Wednesday; join whenever you want and you can see what the community is talking about.

 

Continue reading “DIY Neuroscience Hack Chat” →

Plant Communication Hack Chat

January 11, 2021 by 12 Comments

Join us on Wednesday, January 13th at noon Pacific for the Plant Communication Hack Chat with Lex Kravitz!

As far as conversation goes, plants are usually a pretty poor choice of partners. Sure, we’ve all heard that talking to you houseplants is supposed to be good for them, but expecting them to talk back in any meaningful way is likely to end in disappointment.

Or is it? For as simple and inanimate as plants appear to be, they actually have a rich set of behaviors. Plants can react to stimuli, moving toward attractants like light and nutrients and away from repellents. Some trees can secrete substances to prevent competitors crowding around them, by preventing their seedlings from ever even taking root. And we’ve known for a long time that plants can communicate with each other, through chemical signaling.

Plants are clearly capable of much more than just sitting there, but is there more to the story? Neuroscientist Lex Kravitz thinks so, which is why he has been wiring up his houseplants to sensitive amplifiers and looking for electrical signals. While the bulk of what we know about plant communications is centered on the chemical signals they send, it could be that there’s an electrical component to their behaviors too. Join us as Lex stops by the Hack Chat to talk about his plant communication experiments, and to see if it may someday be possible to listen in on what your plants are saying about you.

join-hack-chatOur Hack Chats are live community events in the Hackaday.io Hack Chat group messaging. This week we’ll be sitting down on Wednesday, January 13 at 12:00 PM Pacific time. If time zones have you tied up, we have a handy time zone converter.

Click that speech bubble to the right, and you’ll be taken directly to the Hack Chat group on Hackaday.io. You don’t have to wait until Wednesday; join whenever you want and you can see what the community is talking about.

Continue reading “Plant Communication Hack Chat” →