A Low Budget DIY Vibrotactile Stimulator For Experimental CRS

February 18, 2023 by Dave Rowntree 6 Comments

Modern techniques of Coordinated Reset Stimulation (CRS), which is usually administered with invasive deep brain stimulation, can have a miraculous effect on those suffering from Parkinson’s disease. However, the CRS technique can also apparently be administered via so-called vibrotactile CRS (vCRS) which essentially means vibrating certain nerve endings corresponding to brain regions that have a large cortical representation.

An example is vibrating the tips of the fingers using special gloves. This is a medical technique and as such is governed by the FDA. With ongoing trials, patients all around the world will simply have to wait. [HackyDev] has been working with a group of people on developing an open source vCRS glove.

This neuromodulation technique seems so promising, that this upfront effort by hackers around the world is simply a joy to see. Patents be dammed; we can work around them. Interested parties can follow the (very long, tricky-to-follow) thread here.

The hardware [HackyDev] put together uses a nodeMCU as the controller, driving eight motor coils via MOSFETS. The finger-mounted actuators are constructed by ripping the electromagnet out of a relay and mounting it in a 3D printed frame, with a magnet suspended on a spring. This part is mounted on each finger. The nodeMCU presents a simple web form that enables the configuration of the pulse parameters.

A permanent magnet is housed in the spring’s top section

The way the gloves appear to work is due to the way the body perceives sensory input, with a massive bias towards the hands and mouth region, referred to as the cortical homunculus. Each finger has an individual haptic element, which is actuated in a specific sequence with a carefully formed pulse at approx. 250 Hz.

This appears to activate similar in-brain effects as traditional (and invasive) DBS therapy by effectively de-synchronizing certain over-synchronized brain pathways and alleviating the overactive ß-wave activity in the brain. And this calms the tremors as well as many other PD symptoms. It’s all very exciting stuff, and we’ll be following this story closely.

For more on the backstory check out the 2017 paper by Peter A. Tass, as well as this later one, and this one. We’ve seen some recent success with diagnosing or at least detecting PD, by smell as well as via audio, so the future might look a little brighter for quite a number of people.

Shocking Tinnitus Therapy Is Music To Sufferers’ Ears

October 16, 2020 by Kristina Panos 67 Comments

Do you suffer from tinnitus? We were surprised to learn that 15-20% of people have this condition that amounts to constant ringing in the ears. Science doesn’t fully understand the ringing part, but one possible explanation is that the brain is compensating for the frequencies it can’t hear any more.

[Hubert Lim], a biomedical engineer at the University of Minnesota discovered that the brain can be stimulated to the point of suppressing tinnitus for as long as one year. [Lim] discovered this by accident while doing deep brain stimulation on a patient with tinnitus. The electrode strayed a bit, touching other areas of the brain and the patient suddenly exclaimed that they couldn’t hear their tinnitus anymore.

Then [Lim] and his team tested guinea pigs, searching here, there, and under the armpits for the best place to suppress tinnitus. As it turns out, the tongue is one of the best places when used along with a specific soundscape. So then they did a human trial with 326 people. Each person had a small paddle electrode on their tongue and headphones on their ears.

As the electrodes sparkled like Pop Rocks against their tongues, the trial participants listened to pure frequencies played over a background of sound resembling vaporwave music. The combination of the two overstimulates the brain, forcing it to suppress the tinnitus reaction. This discovery certainly seems like a game changer for tinnitus sufferers. If we had tinnitus, we would be first in line to try this out given the chance. Armed with the soundscape, we’re left to wonder how many 9V batteries we’d have to lick to approximate the paddle.

Speaking of taste, have you ever experienced all five at once? Here’s a device that simulates them all.