folding at home

2 Articles

Help Us Throw More Cycles At The Coronavirus Problem

May 10, 2020 by 45 Comments

The Hackaday community has answered the call and put their computers put to work folding proteins found in the coronavirus. Team_Hack-a-Day ranks #44 in the world so far this month, and I’ve seen us rank as high as #19 on 24-hour leaderboards.

Want to join the fight? Donate some of those computing cycles you’re not using to battling SARS‑CoV‑2. You’re probably not an epidemiologist or a vaccine researcher, but you can make their jobs easier by providing them with the data they need through the Folding@home Project.

As Dan Maloney explained in his excellent article on protein folding, understanding the incredibly complex folding behavior of the proteins in the virus will be key to finding treatments and possibly a vaccine. Folding@home connects countless computers via the internet and is now the largest supercomputer in the world, consisting of over 3.5 million CPUs and over half a million GPUs. The resulting data is freely available to researchers.

Let’s take a look at how easy it is to get up and running, how a GPU can supercharge a setup, and dip into the stats for Team_Hack-a-Day’s effort.

Continue reading “Help Us Throw More Cycles At The Coronavirus Problem” →

So What Is Protein Folding, Anyway?

April 14, 2020 by 26 Comments

The current COVID-19 pandemic is rife with problems that hackers have attacked with gusto. From 3D printed face shields and homebrew face masks to replacements for full-fledged mechanical ventilators, the outpouring of ideas has been inspirational and heartwarming. At the same time there have been many efforts in a different area: research aimed at fighting the virus itself.

Getting to the root of the problem seems to have the most potential for ending this pandemic and getting ahead of future ones, and that’s the “know your enemy” problem that the distributed computing effort known as Folding@Home aims to address. Millions of people have signed up to donate cycles from spare PCs and GPUs, and in the process have created the largest supercomputer in history.

But what exactly are all these exaFLOPS being used for? Why is protein folding something to direct so much computational might toward? What’s the biochemistry behind this, and why do proteins need to fold in the first place? Here’s a brief look at protein folding: what it is, how it happens, and why it’s important.

Continue reading “So What Is Protein Folding, Anyway?” →