Fluidic Contact Lens Treats Glaucoma

We’ve always been interested in fluidic computers, a technique that uses moving fluids to perform logic operations. Now, Spectrum reports that researchers have developed an electronics-free contact lens that monitors glaucoma and can even help treat it.

The lens is made entirely of polymer and features a microfluidic sensor that can monitor eye pressure in real time. It also has pressure-activated drug reservoirs that dispense medicine when pressure exceeds a fixed threshold. You can see Spectrum’s video on the device below.

This isn’t the first attempt to treat glaucoma, which affects more than 80 million people, with a contact lens. In 2016, Triggerfish took a similar approach, but it used electronic components in the lens, which poses problems for manufacturing and for people wearing them.

Naturally, the device depends on 3D printed molds to create channels and reservoirs in the lens. A special silk sponge in the reservoirs can absorb up to 2,700 times its weight. One sponge holds a red fluid that is forced by pressure into a serpentine microchannel. A phone app uses a neural network to convert the image of the red fluid into a pressure reading.

Two more sponges hold drugs that release at a given pressure determined by the width of the associated microchannel. This allows the possibility of increasing the dose at a higher pressure or even delivering two drugs at different pressure levels.

It is fairly hard to hack your own contact lenses, although we’ve seen it at least once. But smart contacts are not as rare as you might think.

Continue reading “Fluidic Contact Lens Treats Glaucoma”

Emergency Bolt-Action Launcher For EpiPens

Imagine you and your friend are enjoying a nice sunny day, and BAM — they start to have a severe allergic reaction to who knows what. You have an EpiPen, but your friend is on the other side of a field! The solution? Obviously [Emily The Engineer] has only one option: build an entire EpiPen launcher!

Starting off the life-saving project, [Emily] prototyped with a 3D printed blank and a simple solenoid-controlled glorified potato cannon. This proved effective, as one would expect of such a project after successful tests on a human subject. However, there was one simple problem: what if you missed your initial shot?

To ensure no possible failed missions, a bolt-action magazine was retrofitted onto the device. Additionally, an air compressor placed in a mobile backpack carrier allows for repeated mobile use. Official testing was done on ballistic gel before a “war game” scenario played out involving an anaphylactic friend. As one would assume, this went perfectly, ignoring the time delay of having to wait for the compressor to build up enough pressure…

Anyways, even if you won’t be using this EpiPen launcher anytime soon, there are some actual DIY medical miracles you can look into! Something that’s a tad less insane to hack together than an EpiPen gun would be a splint. That is exactly what you can learn about here!

Continue reading “Emergency Bolt-Action Launcher For EpiPens”

Bacteria Marching To The Beat Of A Tiny Drum

Traditionally, identifying a bacterium requires peering through a microscope. Researchers from TU Delft want to trade your eyes for your ears when identifying bacteria. This is possible because they’ve crafted nanoscale drums that convert bacteria’s movement into sound.

The technique originated when Delft researchers noticed something odd. If a living bacterium were on a graphene sheet, it would beat a distinctive pattern that you can detect with a laser. Each drumhead consists of two graphene sheets laid over an 8-micrometer-wide cavity. The sheets are less than a nanometer thick.

The sounds are due to the subtle motion of the tiny lifeform. Scientists have known about these motions, but previously had to measure them en masse. The tiny drums can respond to a single organism, typically about 1 to 10 micrometers in size.

Graphene makes this sensor possible because it is thin enough to behave like a drum with such a tiny force, yet also strong enough to support the bacterium. At first, the technique was simply to determine if antibiotics were killing the bacteria. However, they found that specific bacteria produced audio with unique spectrograms.

It is foolproof, but machine language models can identify among three common bacteria with nearly 90% accuracy. The next step is to reduce the high-tech research setup to something practical for a hospital or doctor’s office. Early prototypes are now in use in two hospitals.

We’ve seen the benefits of automated microscopes that can detect a particular disease. This technology, refined, could go even further.

Figure 1 from the paper: the apparatus and a disintegration fingerprint.

IDing Counterfeit Drugs Might Be Easier Than You Think

Odds are, you’ve taken pills before; it’s a statistical certainty that some of you reading this took several this morning. Whenever you do, you’re at the mercy of the manufacturer: you’re trusting that they’ve put in the specific active ingredients in the dosage listed on the package. Alas, given the world we live in, that doesn’t always happen. Double-checking actual concentrations requires expensive lab equipment like gas chromatography. It turns out checking for counterfeit pills is easier than you’d think, thanks to a technique called Disintegration Fingerprinting.

Continue reading “IDing Counterfeit Drugs Might Be Easier Than You Think”

Blood Tests Could Provide Early Warning Of Alzheimers Disease

Alzheimer’s disease remains a frustratingly difficult condition to manage for the millions of patients affected worldwide and their families. The cause of the disease is still not properly understood, and by the time memory loss and cognitive decline become apparent, the underlying brain pathology has often been quietly building for decades.

Soon, though it may be possible to diagnose impending Alzheimer’s disease ahead of time, before symptoms have taken hold. New research suggests this could be achieved through a simple blood draw, providing clinicians and patients precious time to manage the condition and plan ahead. Continue reading “Blood Tests Could Provide Early Warning Of Alzheimers Disease”

What The FDA’s 2026 Wellness Device Update Means For Wearables

With more and more sensors being crammed into the consumer devices that many of us wear every day, the question of where medical devices begin and end, and how they should be regulated become ever more pertinent. When a ‘watch’ no longer just shows the time, but can keep track of a dozen vital measurements, and the line between ‘earbud’ and ‘hearing aid’ is a rather fuzzy one, this necessitates that institutions like the US FDA update their medical device rules, as was done recently in its 2026 update.

This determines how exactly these devices are regulated, and in how far their data can be used for medical purposes. An important clarification made in the 2026 update is the distinction between ‘medical information’ and ‘signals/patterns’. Meaning that while a non-calibrated fitness tracker or smart watch does not provide medically valid information, it can be used to detect patterns and events that warrant a closer look, such as indications of arrhythmia or low blood oxygen saturation.

As detailed in the IEEE Spectrum article, these consumer devices are thus  ‘general wellness’ devices, and should be marketed as such, without embellished claims. Least of all should they be sold as devices that can provide medical information.

Continue reading “What The FDA’s 2026 Wellness Device Update Means For Wearables”

Motorola’s Password Pill Was Just One Idea

Let’s face it; remembering a bunch of passwords is the pits, and it’s just getting worse as time goes on. These days, you really ought to have a securely-generated key-smash password for everything. And at that point you need a password manager, but you still have to remember the password for that.

Well, Motorola is sympathetic to this problem, or at least they were in 2013 when they came up with the password pill. Motorola Mobility, who were owned by Google at the time, debuted it at the All Things Digital D11 tech conference in California. This was a future that hasn’t come to pass, for better or worse, but it was a fun thought experiment in near-futurism.

Continue reading “Motorola’s Password Pill Was Just One Idea”