Medical Hacks

687 Articles

Gene Therapy Aims To Slow Huntington’s Disease To A Crawl

November 11, 2025 by 21 Comments

Despite the best efforts of modern medicine, Huntington’s disease is a condition that still comes with a tragic prognosis. Primarily an inherited disease, its main symptoms concern degeneration of the brain, leading to issues with motor control, mood disturbance, with continued degradation eventually proving fatal.

Researchers have recently made progress in finding a potential treatment for the disease. A new study has indicated that an innovative genetic therapy could hold promise for slowing the progression of the disease, greatly improving patient outcomes.

Continue reading “Gene Therapy Aims To Slow Huntington’s Disease To A Crawl” →

The Strange Depression Switch Discovered Deep Inside The Brain

November 10, 2025 by 49 Comments

As humans, we tend to consider our emotional states as a direct response to the experiences of our lives. Traffic may make us frustrated, betrayal may make us angry, or the ever-grinding wear of modern life might make us depressed.

Dig into the science of the brain, though, and one must realize that our emotional states are really just electrical signals zinging around our neurons. And as such, they can even be influenced by direct electrical stimulation.

One group of researchers found this out when they inadvertently discovered a “switch” that induced massive depression in a patient in mere seconds. For all the complexities of the human psyche, a little electricity proved more than capable of swaying it in an instant.

Continue reading “The Strange Depression Switch Discovered Deep Inside The Brain” →

Reshaping Eyeballs With Electricity, No Lasers Or Cutting Required

October 8, 2025 by 36 Comments

Glasses are perhaps the most non-invasive method of vision correction, followed by contact lenses. Each have their drawbacks though, and some seek more permanent solutions in the form of laser eye surgeries like LASIK, aiming to reshape their corneas for better visual clarity. However, these methods often involve cutting into the eye itself, and it hardly gets any more invasive than that.

A new surgical method could have benefits in this regard, allowing correction in a single procedure that requires no lasers and no surgical cutting of the eye itself. The idea is to use electricity to help reshape the eye back towards greater optical performance.

Continue reading “Reshaping Eyeballs With Electricity, No Lasers Or Cutting Required” →

capsule shown with magnetic fields represented with arrows

Pill Sized Scoop Of Your Internals

September 24, 2025 by 4 Comments

Taking a look inside the human body has never been easier — just swallow a camera in the shape of a pill. However, what is not quite as easy is retrieving a piece of whatever you’re viewing. This is exactly what researchers from HIT Shenzhen have attempted to solve with their magnetic capsule bot.

When traditional procedures want to take a sample somewhere in the intestinal tract they generally require somewhat invasive procedures sticking something up…well you know. With this pill, robot magnetic control allows physicians to choose exactly where and when to take a sample, all without shoving unpleasant objects into…again you know.

A magnetic field is generated to open the capsule and suck liquids inside. This traps a sample that can be retrieved through later bowel movements. The technology hasn’t been tested on a living patient yet, but but animal trials are planned for the foreseeable future.

Check out the fine details with the paper itself here. Biomedical engineering is always an interesting topic with so much potential for more hacking. We at Hackaday are no strangers to this wonderful world of bodily hacks.

Heart Rate Measurement Via WiFi, The DIY Way

September 23, 2025 by 13 Comments

A few weeks back, we reported on a research group that figured out how to measure heartrate using perturbations in WiFi signals. [Nick Bild] was interested in this so-called “Pulse-Fi” technique, but noted the paper explaining it was behind a paywall. Thus, he worked to recreate the technology himself so he could publish the results openly for anyone eager to learn.

[Nick] paid for the research paper, and noted that it was short on a few of the finer details and didn’t come with any code or data from the original research team. He thus was left to figure out the finer details of how to measure heart rate via WiFi in his own way, though he believes his method is quite close to the original work.

The basic concept is simple enough. One ESP32 is set up to transmit a stream of Channel State Information packets to another ESP32, with a person standing in between. As the person’s heart beats, it changes the way the radio waves propagate from the transmitting unit to the receiver. These changes can be read from the packets, and processed to estimate the person’s heart rate. [Nick] explains the various data-massaging steps involved to go from this raw radio data to a usable heart rate readout.

It’s a great effort from [Nick] to recreate this research all on his own in his home lab. Files are on GitHub for the curious. If you’re eager to learn more about these innovative measurement techniques, you might like to read our prior reporting on the tech. Also, it’s worth remembering—don’t use your homebrew prototypes for any serious healthcare purposes. Continue reading “Heart Rate Measurement Via WiFi, The DIY Way” →

A piece of perovskite crystal

Perovskite Solar Cell Crystals See The Invisible

September 16, 2025 by 14 Comments

A new kind of ‘camera’ is poking at the invisible world of the human body – and it’s made from the same weird crystals that once shook up solar energy. Researchers at Northwestern University and Soochow University have built the first perovskite-based gamma-ray detector that actually works for nuclear medicine imaging, like SPECT scans. This hack is unusual because it takes a once-experimental lab material and shows it can replace multimillion-dollar detectors in real-world hospitals.

Current medical scanners rely on CZT or NaI detectors. CZT is pricey and cracks like ice on a frozen lake. NaI is cheaper, but fuzzy – like photographing a cat through steamed-up glass. Perovskites, however, are easier to grow, cheaper to process, and now proven to detect single photons with record-breaking precision. The team pixelated their crystal like a smartphone camera sensor and pulled crisp 3D images out of faint radiation traces. The payoff: sharper scans, lower radiation doses, and tech that could spread beyond rich clinics.

Perovskite was once typecast as a ‘solar cell wonder,’ but now it’s mutating into a disruptive medical eye. A hack in the truest sense: re-purposing physics for life-saving clarity.

Antiviral PPE For The Next Pandemic

August 19, 2025 by 35 Comments

In what sounds like the plot from a sci-fi movie, scientists have isolated an incredibly rare immune mutation to create a universal antiviral treatment.

Only present in a few dozen people worldwide, ISG15 immunodeficiency causes people to be more susceptible to certain bacterial illnesses, but it also grants the people with this condition immunity to known viruses. Researchers think that the constant, mild inflammation these individuals experience is at the root of the immunoresponse.

Where things get really interesting is how the researchers have found a way to stimulate protein production of the most beneficial 10 proteins of the 60 created by the natural mutation using 10 mRNA sequences inside a lipid nanoparticle. Lead researcher [Dusan Bogunovic] says “we have yet to find a virus that can break through the therapy’s defenses.” Researchers hope the treatment can be administered to first responders as a sort of biological Personal protective equipment (PPE) against the next pandemic since it would likely work against unknown viruses before new targeted vaccines could be developed.

Hamsters and mice were given this treatment via nasal drip, but how about intranasal vaccines when it comes time for human trials? If you want a short history of viruses or to learn how smartwatches could help flatten the curve for the next pandemic, we’ve got you covered.