Pneumatic Glove For Therapy And Experimentation

February 12, 2020 by Lewin Day 3 Comments

Many projects have aimed to replicate the function of the human hand, creating robotic structures that mimic real anatomy. Fewer have attempted to work with human hands directly. SoftGlove is a project by [france.bonde] that uses pneumatics to do just that.

The glove works by using a silicone pneumatic actuator for each digit on the human hand, attached to a glove. These are created with 3D printed molds, into which EcoFlex silicone is poured. A FlowIO device is used to run the pneumatics, which combines a microcontroller with penumatic hardware to pump air in and out of the actuators.

The goal of the project is to use a companion unit, in which a glove with flex sensors is used to make the SoftGlove mimic its movements. This would allow SoftGlove to move the fingers of a person with damaged muscle control, potentially aiding the muscles and nerves to recover when used in a therapeutic setting.

It’s exciting to see typical maker technologies used in a context to create better outcomes for patients, and we’re excited to see where this project leads next. It also has potential applications for robotic actuators, too. Programmable Air is another exciting project working in this space, too. And of course, if you’ve got a hot pneumatics project you’re cooking up in the garage, be sure to let us know!

Hacked Protective Gear Keeps Doctor Safe In The Hot Zone

February 12, 2020 by Dan Maloney 33 Comments

It’s rarely a wise idea to put a plastic bag over one’s head, but when the choice is between that and possibly being exposed to a dangerous virus, you do what you have to. So you might as well do it right and build a field-expedient positive pressure hood.

We’ve all been keeping tabs on the continuing coronavirus outbreak in China, but nobody is following as closely as our many friends in China. Hackaday contributor [Naomi Wu] is in from Shenzhen, ~~posting regularly from the quarantined zone~~, and she found this little gem of ingenuity from a [Doctor Cui] in one of the hospitals in Wuhan. Quarantines and travel restrictions have put personal protective equipment like masks and gowns in limited supply, with the more advanced gear needed by those deal most closely with coronavirus patients difficult to come by.

There’s no build information, but from the pictures we can guess at what [Dr. Cui] came up with. The boxy bit is an AirPro Car, a HEPA filter meant to clean the cabin air in a motor vehicle. He glued on a USB battery pack to power it, used a scrap of plastic and some silicone adhesive to adapt a heat-moisture exchange filter from a mechanical ventilator to the AirPro’s outlet, and stuck the tube into a plastic bag sealed around his neck. The filter provides dry, positive pressure air to keep the bag from fogging up, and to keep [Dr. Cui] from asphyxiating. Plus he’s protected from droplet contact, which is a big plus over simple paper masks.

With the news always so dark, it’s heartening to see stories of ingenuity like this. We wish [Dr. Cui] and all our friends in China the best during this outbreak.

Ask Hackaday: What’s Your Coronavirus Supply Chain Exposure?

February 10, 2020 by Dan Maloney 128 Comments

In whichever hemisphere you dwell, winter is the time of year when viruses come into their own. Cold weather forces people indoors, crowding them together in buildings and creating a perfect breeding ground for all sorts of viruses. Everything from the common cold to influenza spread quickly during the cold months, spreading misery and debilitation far and wide.

In addition to the usual cocktail of bugs making their annual appearance, this year a new virus appeared. Novel coronavirus 2019, or 2019-nCoV, cropped up first in the city of Wuhan in east-central China. From a family of viruses known to cause everything from the common cold to severe acute respiratory syndrome (SARS) in humans, 2019-nCoV tends toward the more virulent side of the spectrum, causing 600 deaths out of 28,000 infections reported so far, according to official numbers at the time of this writing.

(For scale: the influenzas hit tens of millions of people, resulting in around four million severe illnesses and 500,000 deaths per season, worldwide.)

With China’s unique position in the global economy, 2019-nCoV has the potential to seriously disrupt manufacturing. It may seem crass to worry about something as trivial as this when people are suffering, and of course our hearts go out to the people who are directly affected by this virus and its aftermath. But just like businesses have plans for contingencies such as this, so too should the hacking community know what impact something like 2019-nCoV will have on supply chains that we’ve come to depend on.

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Florence Nightingale: The Lady With The Data

February 4, 2020 by Kristina Panos 15 Comments

When you think of Florence Nightingale, you probably imagine a nurse with a lamp, comforting soldiers. Indeed, Florence is considered the mother of modern nursing. But she also made serious contributions in statistical data analysis, and used the diagram named after her, the Nightingale rose diagram, to convince the British Parliament to enact sanitation reforms that saved hundreds of thousands, if not millions, of lives.

During the Crimean war, Florence worked around the clock as head nurse in an overcrowded field hospital. But she also found time to create graphs to illustrate the terrible conditions of that field hospital to members of British Parliament. The sanitation reforms she led greatly improved the life of the soldiers in battle, and widespread adoption of her hygienic practices vastly reduced mortality rates of humanity in general.

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Art Imitates DNA

February 1, 2020 by Al Williams 8 Comments

It has recently been possible to pay a service a little bit of money and learn more about your own DNA. You might find out you really aren’t Italian after all or that you are more or less susceptible to some ailments. [Paul Klinger] had his DNA mapped and decided to make a sculpture representing his unique genetic code. The pictures are good, but the video below is even better.

The project requires a DNA sequencing, a 3D printer, and a Raspberry Pi Zero. Oh, you can probably guess you need a lot of RGB LEDs, too. Of course, the display doesn’t show the whole thing at one time — your DNA pattern scrolls across the double helix.

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CRISPR Could Fry All Cancer Using Newly Found T-Cell

January 27, 2020 by Kristina Panos 36 Comments

One of the human body’s greatest features is its natural antivirus protection. If your immune system is working normally, it produces legions of T-cells that go around looking for abnormalities like cancer cells just to gang up and destroy them. They do this by grabbing on to little protein fragments called antigens that live on the surface of the bad cells and tattle on their whereabouts to the immune system. Once the T-cells have a stranglehold on these antigens, they can release toxins that destroy the bad cell, while minimizing collateral damage to healthy cells.

CAR T-cell therapy process via National Cancer Institute

This rather neat human trick doesn’t always work, however. Cancer cells sometimes mask themselves as healthy cells, or they otherwise thwart T-cell attacks by growing so many antigens on their surface that the T-cells have no place to grab onto.

Medical science has come up with a fairly new method of outfoxing these crafty cancer cells called CAR T-cell therapy. Basically, they withdraw blood from the patient, extract the T-cells, and replace the blood. The T-cells are sent off to a CRISPR lab, where they get injected with a modified, inactive virus that introduces a new gene which causes the T-cells to sprout a little hook on their surface.

This hook, which they’ve dubbed the chimeric antigen receptor (CAR), allows the T-cell to chemically see through the cancer cells’ various disguises and attack them. The lab multiplies these super soldiers and sends them back to the treatment facility, where they are injected into the patient’s front lines.

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Tracking Cancer Treatment With An ESP8266-Based Radiation Sensor

January 25, 2020 by Jenny List 22 Comments

Those of us who have not been in that position can only imagine the anguish of learning that your teenager has cancer. This happened to [Rob], whose child was diagnosed with papillary thyroid cancer. It’s a condition that can be treated with surgery followed by a course of radioactive iodine to kill any remaining cancer cells. During iodine treatment, the patient is radioactive enough that other people must maintain a distance of 3m from them, and as a learning exercise for both father and teen he created and refined the design of a portable wireless radioactivity monitor.

There are a variety of sensors for radiation monitoring including the well-known Geiger–Müller tube, but he settled on a PIN photodiode based sensor supplied by radiation-watch.org. This sensor is not at its most sensitive at the energy levels emitted by the iodine isotope used in the treatment, but the relatively high intensity of the radiation meant that enough would register for a useful reading to be taken. The sensor board he was mated to an ESP8266 module. [Rob] went through three iterations of the balance of the hardware before settling on a lithium-ion battery and a plastic case.

On the software side, the ESP connects to an MQTT server, from which a CSV file of data is derived. On a computer, the CSV data is collected and plotted to a graph. The data take during treatment clearly shows the reduction in radiation following the isotope’s half-life. The graph isn’t perfect though, there is a gap due to the second prototype’s batteries running flat

From his epilogue it appears that his son has recovered, and we wish them further good health. The details have been published in the hope that other young people facing the same trial might benefit from building their own radiation monitor.