Printing Soft Body Tissue

If you are like us, you tend to do your 3D printing with plastic or maybe–if you are lucky enough to have access to an expensive printer–metal. [Adam Feinberg] and his team at Carnegie Mellon print with flesh. Well, sort of. Printing biomaterials is a burgeoning research area. However, printing material that is like soft tissue has been challenging. In a recent paper, [Feinberg] and company outline a method called FRESH. FRESH uses a modified MakerBot or Printrbot Jr. printer to deposit hydrogel into a gelatin slurry support bath. The gelatin holds the shape of the object until printing is complete, at which point it can be removed with heat. If you don’t want to wade through the jargon in the actual paper, the journal Science has a good overview (and see their video below).

The gelatin is mixed with calcium chloride and gelled for 12 hours at low temperature. It was then turned into a slurry using an off-the-shelf consumer-grade blender. A centrifuge was used to remove most of the soluble gelatin. Printing inks were made with materials like collagen and fibrin. The FRESH process actually uses liquid  ink that gels in the gelatin.

The printer uses an open source syringe extruder found on the NIH 3D print exchange (they never say exactly  which one, though and we had trouble matching it from the pictures). In true hacker fashion, the printer prints its own syringe extruder using the stock one from ABS and PLA plastic. Then you simply replace the standard extruder with the newly printed one (reusing the stock stepper motor).

The paper describes printing items including a model of a 5-day-old embryonic chick heart, an artery, and a miniature human brain model. Another team of researchers in Florida have a similar system, as well.

We’ve talked about bioprinting before and even mentioned how to make your own inkjet-based bioprinter. The FRESH method looks like it is in reach of the hacker’s 3D printing workshop. We cringe to think what you will print when you can finally print body parts.

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Hacking When It Counts: Surviving The Burma Death Railway

In the early days of World War II, the Japanese army invaded Burma (now Myanmar) and forced an end to British colonial rule there. Occupying Burma required troops and massive amounts of materiel, though, and the Japanese navy was taking a beating on the 2,000 mile sea route around the Malay Peninsula. And so it was decided that a railway connecting Thailand and Burma would be constructed through dense tropical jungle over hilly terrain with hundreds of rivers, including the Kwae Noi River, made famous by the Hollywood treatment of the story in The Bridge on the River Kwai. The real story of what came to be known as the Burma Death Railway is far grislier than any movie could make it, and the ways that the prisoners who built it managed to stay alive is a fascinating case study in making do with what you’ve got and finding solutions that save lives.

Nutrition from Next-to Nothing

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POWs in camp. [Source: The Thai-Burma Railway and Hellfire Pass]
Labor for the massive project was to come from the ultimate spoil of war – slaves. About 250,000 to 300,000 slaves were used to build the Burma-Siam Railway. Among them were about 60,000 Allied prisoners of war, primarily Australian, Dutch, British and American. POWs were singled out for especially brutal treatment by the Japanese and Korean guards, with punishment meted out with rifle butt and bamboo pole.

With the POWs was Doctor Henri Hekking, who had been born and raised in the former Dutch East Indies colony of Java (now Indonesia). He had spent his early years with his grandmother, a master herbalist who served as “doctor” for the native villagers. Inspired by his oma’s skill and convinced that the cure for any endemic disease can be found in the plants in the area, Dr. Hekking returned to Java as an officer in the Dutch army after completing medical school in the Netherlands.

After his capture by the Japanese, Dr. Hekking did everything he could to help his fellow POWs despite the complete lack of medical supplies, all the while suffering from the same miserable treatment. Hekking realized early on that the starvation rations the POWs endured were the main cause of disease in the camps; a cup of boiled white rice doesn’t provide much energy for men building a railway by hand in jungle heat, and provides none of the B vitamins needed by the body.

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Nurses Create In A Medical Makerspace

Although there are many skilled and dedicated types of health care professionals, nurses are often the main point of contact between the medical establishment and a patient. You will probably spend more time with your nurse–especially in a hospital setting–than any other health care provider. Every patient’s needs are different, so it isn’t surprising that nurses sometimes improvise unique solutions to help their patients be more comfortable or recover faster.

That’s the idea guiding an innovative program called MakerNurse–an initiative backed by MIT and the Robert W. Johnson Foundation. The idea is to encourage nurses to be makers. One of the project’s cofounders, Anna Young, had found nurses in Central America making do with what they had on hand and naturally acting as makers. “We saw a nurse repair a stethoscope diaphragm with an overhead transparency,” she said. Young noted that often nurses didn’t realize the significance of their making–it was just how they got through the day.

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CyberPunk Yourself – Body Modification, Augmentation, And Grinders

“We accept pain as a price of doing business, even if it is just for aesthetic purposes. You want to put a magnet in your finger, a doctor will ask you why; a mod artist will ask when you can start.” As with many other people who are part of the growing grinder movement, [Adam] has taken a step that many would consider extreme – he’s begun to augment his body.

Grinders – men and women who hack their own bodies – are pushing the boundaries of what is currently possible when it comes to human augmentation. They’re hackers at heart, pursuing on an amateur level what they can’t get from the consumer market. Human augmentation is a concept that is featured heavily in science fiction and futurism, but the assumption most people have is that those kinds of advancements will come from medical or technology companies.

Instead, we’re seeing augmentation begin in the basements of hackers and in the back rooms of piercing studios. The domain of grinders is the space where body modification and hacking meet. It mixes the same willingness to modify one’s body that is common among the tattooed and pierced, and adds an interest in hacking technology that you find in hackerspaces around the world. When those two qualities intersect, you have a potential grinder.

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Push Blood Pressure Data To The Cloud Via ESP8266

[Eduardo] contacted us about his success at connecting a blood pressure monitor to the web. He pulled this off by locating the chip responsible for storing the blood pressure data after being measured. It was a simple I2C EEPROM from which he dumped the data a sniffed communications with a 4 bit logic analyzer. [Eduardo] published all of his findings on that communication scheme so check out his post for more on that. The gist of it is that he implemented his reverse engineered protocol using an ESP8266, the ubiquitous cheap WiFi board that has become a go-to for web-connected anything like power monitors and underpowered but awesome server farms. Check out the Hackaday Dictionary entry for more on this board.

[Eduardo] is not the first on the scene with such a device, you can see a Withings device and a blipcare device available on Amazon. What this hack from [Eduardo] does provide is evidence of a much cheaper route for connecting vital medical data from a geographically distant, and perhaps technophobic family member. Lets take a walk down hypothetical lane, shall we? Uncle Bob in Albuquerque who doesn’t have any local family might be a good candidate for such a hacked device, everyone knows it’s like pulling teeth to get elderly family members to report some health information to loved ones… but with [Eduardo’s] hack it’s simple. Embed the hardware (assuming you know the login creds ahead of time) into a new BPM, send it to him as a gift, and Bob’s your uncle.

We haven’t seen too many blood pressure monitor hacks, but one entry from the Hackaday Prize dubbed “the pain machine” included monitoring the user’s blood pressure. We also covered an interesting hack on monitoring your heart rate with a piezo element.

A quick demo of [Edward’s] cuff is found below.

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Can You Hear Me Now?

It’s great to build projects just to do something neat, to learn; to impress friends and other hackers. It’s even better to address a real need.

I’ve worn hearing aids for 40 some years. My response to the question “Can you hear me now?” is still all too often, “No.” Because of this I heartily applaud the Aegis Acoustics Headset currently active on Kickstarter. I’m happy to see it’s blown through its goal with over a month left.

The Aegis is targeted at prevent hearing loss, primarily in teens since they use headsets so often. It’s equally applicable to adults and pre-teens. The Aegis works by limiting the sound level emitted to 85db, which is a safe level. Above that the risk of damage to the tiny hairs in the cochlea – the inner ear – increases dramatically with a 3db increase cutting the safety time in half.

Future’s So Bright I’ve Got to Wear ‘Aids

My personal experience explains why this is important. At my first professional level job as a software developer I noticed that people at the other end of the table often mumbled during meetings. Not really, because everyone else understood them fine. I needed hearing aids.

My first hearing aids were analog devices. There were three frequency bands across the audio spectrum whose volumes could be custom set for my ears — resulting in crude and limited improvements in what I could hear. My current hearing aids are technological marvels of digital signal processing with a multitude of algorithms the audiologist can use to help me hear better. They even coordinate their actions by communicating between themselves.

I still need to ask people to repeat what they say at times. But who doesn’t? I had a successful career despite my loss. But it is still a royal pain-in-the-butt to miss out on one-third of the dialog in a movie, to not go to a local coffee house because I won’t understand the lyrics or comments by the musicians, and miss out on all the other small parts of life along these lines.

Hacking for Hearing

There are a range of areas where hackers could contribute and not just in assisting individuals, like myself, who personally gain from technological assistance.

Consider how the cell phone improved communications in developing countries. Using radio communications the countries avoided the need to string thousands of miles of wires. That saved the expense and the decades of construction time. It’s easier to get cell phone service than water in some locations. It’s important to notice that it didn’t come about because of a big plan. It came about as an unseen consequence of a technical development.

“We can rebuild him…we have the technology” is from the opening of an old TV series and movies, “The 6 Million Dollar Man” and has found it’s place in the pop-culture vocabulary. But it rings true. We have the technology. We have the tools. We have the expertise. We’re hackers and builders. We and the technology are all over the place. We’re a solution looking for a problem.

Devices that Extend the Body

All signs point to a coming revolution of devices that protect our bodies and make them work better. The 2015 Hackaday Prize theme is Build Something That Matters and that sentiment is obviously taking hold throughout the hardware hacker movement. The Aegis headphones I mentioned above are one example of preventive devices, but look around and there are many more like the UV-Badge which gives you feedback on safe levels of sunlight for your skin.

Surely we’re going to see further augmentation for the devices that help restore function. Wearables are all the rage, how long will it be before your smartwatch notification functions make it into my hearing aids? Imagine the improvements we will see in custom hearing profiles born of that smartphone-hearing aid connection. The foundations of this are user-controlled profile switching which is already in place for apps like Belltone’s HearPlus. If the advanced electronics in the smartphone can build a better noise profile and transfer it to the hearing aid my visits to the coffee shop just might get a lot better. And this doesn’t mean the devices need to look the same either. I love the Design Affairs Studio hearing aid concept that is shown at the top of this article. Hardware can be a status symbol after all.

This type of forward thinking easily extends to all assistive technologies such as wheelchair improvements and navigation systems for the blind.

As you look toward your next big hack, roll these concepts around in your mind. The tools, software, and talent have never been easier to connect for our group of citizen scientists who are hacking in basements and garages. It’s exciting to think about the change we can affect using the skills honed over the past decades of this hardware enlightenment we’re all living.

Hackaday Prize Semifinalist: Individualized Breathing Apparatus

Preterm infants frequently require ventilator support while they’re in the neonatal ICU, and this is usually done with a CPAP machine. The machine to infant interface is called a nasal cannula, a bit of plastic that connects an infant’s nose to the machine. Because there aren’t that many sizes of nasal cannula available, and preemies come in all sizes, there are inevitable problems. Ill-fitting nasal cannula can reduce the effectiveness of a CPAP, and can even cause significant damage to an infant’s septum.

For his Hackaday Prize entry, [Ben] is tackling this problem head on. He’s working on creating individualized nasal cannula for newborns using 3D modeling and printing, allowing nasal cannula of all shapes and sizes to be created in a matter of hours.

To create these customized cannula, [Ben] is 3D scanning an infant mannequin head to gather enough data to import it into a Processing sketch. A custom cannula is then created and printed with flexible 3D printer filament. In theory, it should work, apart from the considerations involved in building a medical device.

As for why custom plastic tubes matter, [Ben] works at the only NICU in Western Australia. Even though he only sees 8-10 CPAP ‘pressure injuries’ in his unit each year, these kids are extremely fragile and some parents have expressed a desire for something that isn’t as uncomfortable for their newborn than the off-the-shelf solution. Customizing these cannula from a quick 3D scan is a great way to do that, and a perfect example of the Hackaday Prize theme of ‘build something that matters.’

The 2015 Hackaday Prize is sponsored by: