Regenerative Medicine: The Promise Of Undoing The Ravages Of Time

In many ways, the human body is like any other machine in that it requires constant refueling and maintenance to keep functioning. Much of this happens without our intervention beyond us selecting what to eat that day. There are however times when due to an accident, physical illness or aging the automatic repair mechanisms of our body become overwhelmed, fail to do their task correctly, or outright fall short in repairing damage.

Most of us know that lizards can regrow tails, some starfish regenerate into as many new starfish as the pieces which they were chopped into, and axolotl can regenerate limbs and even parts of their brain. Yet humans too have an amazing regenerating ability, although for us it is mostly contained within the liver, which can regenerate even when three-quarters are removed.

In the field of regenerative medicine, the goal is to either induce regeneration in damaged tissues, or to replace damaged organs and tissues with externally grown ones, using the patient’s own genetic material. This could offer us a future in which replacement organs are always available at demand, and many types of injuries are no longer permanent, including paralysis. Continue reading “Regenerative Medicine: The Promise Of Undoing The Ravages Of Time”

An Oil Diffusion Vacuum Pump From Thrift Store Junk

It seems like creating a vacuum should be a pretty easy job, but it turns out that sucking all the air out of something is harder than it seems. A cheap vacuum pump will get you part of the way there, but to really pull a hard vacuum, you need an oil diffusion pump that costs multiple tens of thousands of dollars.

Or, you need a bunch of thrift store junk, a TIG welder, and a can of WD-40. At least that’s what [Lucas] put into his homebrew oil diffusion pump. The idea of such a contraption is to vaporize oil in a chamber such that the oil droplets entrain any remaining gas molecules toward an exhaust port. His low-budget realization of this principle involved a lot of thrift store stainless steel cookware, welded together with varying degrees of success, with liberal applications of epoxy to seal up any leaks. And an electric smores cooker for the heating element, which was a nice touch. The low-budget approach extended even to the oil for the pump; rather than shelling out for expensive specialty oil, [Lucas] distilled some from a WD-40 silicone spray lubricant.

The video below details all the travails [Lucas] encountered along the way, plus the testing process. The results were at least encouraging — the diffusion pump was pulling vacuum far in excess of what the roughing pump was capable of. He clearly still has some work to do, but getting as far as he did with the scrap heap of parts he cobbled together is pretty impressive.

[Lucas]’ goal with all this? A fusion reactor. No, not that kind. This kind. Continue reading “An Oil Diffusion Vacuum Pump From Thrift Store Junk”

Digital Rain Animation Crammed Into Pi Pico

With a new Matrix movie now in cinemas, we’ve all been reminded of those screensavers that were just the coolest thing ever when the original film dropped in 1999. [en0b] decided to recreate the classic “digital rain” effect on the Raspberry Pi Pico, using up all the little microcontroller’s storage in the process.

Rather than rely on existing graphics libraries, [en0b] set about using a high-quality GIF for the animation. The original file was 8 MB, which was far too big to fit on the Pico. After some finagling in an image editor and with the help of a custom Python script, however, [en0b] managed to fit the 127-frame animation at 240 x 135 resolution into the 2 MB Flash onboard the chip. With the microcontroller hooked up to the 1.14″ IPS “Pico Display” from Pimoroni, the final looks great and faithfully recreates the aesthetic seen in the film.

[en0b]’s technique could reliably be used for displaying any GIF that you can cut down to 14 to 16 colors without losing too much quality. It’s not the world’s highest-end graphics format, but it does the job for little animations like these.

We’ve seen similar builds before too, using more heavy-duty hardware to build a magic 8-ball in much the same way. Meanwhile, if you’ve got your own neat little GIF hacks or Pico projects, don’t hesitate to send them in!