Washington Consumers Gain Right To Repair For Cellphones And More

May 28, 2025 by Maya Posch 30 Comments

Starting January 1st, 2026, Washington state’s new Right to Repair law will come into effect. It requires manufacturers to make tools, parts and documentation available for diagnostics and repair of ‘digital electronics’, including cellphones, computers and similar appliances. The relevant House Bill 1483 was signed into law last week after years of fighting to make it a reality.

A similar bill in Oregon faced strong resistance from companies like Apple, despite backing another Right to Repair bill in California. In the case of the Washington bill, there were positive noises from the side of Google and Microsoft, proclaiming themselves and their products to be in full compliance with such consumer laws.

Of course, the devil is always in the details, with Apple in particular being a good example how to technically comply with the letter of the law, while throwing up many (financial) roadblocks for anyone interested in obtaining said tools and components. Apple’s penchant part pairing is also a significant problem when it comes to repairing devices, even if these days it’s somewhat less annoying than it used to be — assuming you’re running iOS 18 or better.

That said, we always applaud these shifts in the right direction, where devices can actually be maintained and repaired without too much fuss, rather than e.g. cellphones being just disposable items that get tossed out after two years or less.

Thanks to [Robert Piston] for the tip.

Fixing A Fatal Genetic Defect In Babies With A Bit Of Genetic Modification

May 27, 2025 by Maya Posch 30 Comments

Genetic defects are exceedingly common, which is not surprising considering just how many cells make up our bodies, including our reproductive cells. While most of these defects have no or only minor effects, some range from serious to fatal. One of these defects is in the CPS1 gene, with those affected facing a shortened lifespan along with intensive treatments and a liver transplant as the only real solution. This may now be changing, after the first successful genetic treatment of an infant with CPS1 deficiency.

Carbamoyl phosphate synthetase I (CPS1) is an enzyme that is crucial for breaking down the ammonia that is formed when proteins are broken down. If the body doesn’t produce enough of this enzyme in the liver, ammonia will accumulate in the blood, eventually reaching levels where it will affect primarily the nervous system. As an autosomal recessive metabolic disorder it requires both parents to be carriers, with the severity depending on the exact mutation.

In the case of the affected infant, KJ Muldoon, the CPS1 deficiency was severe with only a low-protein diet and ammonia-lowering (nitrogen scavenging) medication keeping the child alive while a search for a donor liver had begun. It is in this context that in a few months time a CRISPR-Cas9 therapy was developed that so far appears to fixing the faulty genes in the liver cells.

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Mouse Model Suggests Starch-Based Plastics Are Still Bad For You

May 26, 2025 by Maya Posch 48 Comments

To paraphrase The Simpsons: plastics are the solution to – and cause of – all of mankind’s problems. Nowhere is this more clear in the phenomenon of microplastics. Some have suggested that alternative bioplastics made out of starch could be the solution here, as the body might be able to digest and disassemble these plastic fragments better. Unfortunately, a team of Chinese researchers put this to the test using mice, with the results suggesting that starch-based plastics do not change the harm to tissues and organs.

We previously looked at this harm from micro- and nanoplastics (MNP), with humans and their brains at autopsy showing a strong correlation between disease and presence of MNPs. In this recent study mice were split up into three groups, for either no, low or high levels of these bioplastics in their food. At autopsy, the mice exposed to the bioplastics all showed damage to organs, including the same gene-regulation issues and inflammation markers as seen with other plastics.

Despite these results, researchers question how useful these results are, as they pertain to modified starches with known biodegradability issues, while starch by itself is absolutely digestible when it’s in the form of potato chips, for instance. Perhaps the trick here is to make bioplastics that are still useful as plastics, and yet as harmless to ingest as said potato chips.

Not that we recommend eating bioplastics, mind you; potato chips are definitely tastier.

NASA Is Shutting Down The International Space Station Sighting Website

May 26, 2025 by Maya Posch 35 Comments

Starting on June 12, 2025, the NASA Spot the Station website will no longer provide ISS sighting information, per a message recently sent out. This means no information on sighting opportunities provided on the website, nor will users subscribed via the website receive email or text notifications. Instead anyone interested in this kind of information will have to download the mobile app for iOS or Android.

Obviously this has people, like [Keith Cowing] over at Nasa Watch, rather disappointed, due to how the website has been this easy to use resource that anyone could access, even without access to a smart phone. Although the assumption is often made that everyone has their own personal iOS or Android powered glass slab with them, one can think of communal settings where an internet café is the sole form of internet access. There is also the consideration that for children a website like this would be much easier to access. They would now see this opportunity vanish.

With smart phone apps hardly a replacement for a website of this type, it’s easy to see how the app-ification of the WWW continues, at the cost of us users.

Recovering Water From Cooling Tower Plumes With Plume Abatement

May 22, 2025 by Maya Posch 24 Comments

Electrostatic droplet capture system installed on an HVAC condenser. (Credit: Infinite Cooling)

As a common feature with thermal power plants, cooling towers enable major water savings compared to straight through cooling methods. Even so, the big clouds of water vapor above them are a clear indication of how much cooling water is still effectively lost, with water vapor also having a negative impact on the environment. Using so-called plume abatement the amount of water vapor making it into the environment can be reduced, with recently a trial taking place at a French nuclear power plant.

This trial featured electrostatic droplet capture by US-based Infinite Cooling, which markets it as able to be retrofitted to existing cooling towers and similar systems, including the condensers of office HVAC systems. The basic principle as the name suggests involves capturing the droplets that form as the heated, saturated air leaves the cooling tower, in this case with an electrostatic charge. The captured droplets are then led to a reservoir from which it can be reused in the cooling system. This reduces both the visible plume and the amount of cooling water used.

In a 2021 review article by [Shuo Li] and [M.R. Flynn] in Environmental Fluid Mechanics the different approaches to plume abatement are looked at. Traditional plume abatement designs use parallel streams of air, with the goal being to have condensation commence as early as possible rather than after having been exhausted into the surrounding air. Some methods used a mesh cover to provide a surface to condense on, while a commercially available technology are condensing modules which use counterflow in an air-to-air heat exchanger.

Other commercial solutions include low-profile, forced-draft hybrid cooling towers, yet it seems that electrostatic droplet capture is a rather new addition here. With even purely passive systems already seeing ~10% recapturing of lost cooling water, these active methods may just be the ticket to significantly reduce cooling water needs without being forced to look at (expensive) dry cooling methods.

Top image: The French Chinon nuclear power plant with its low-profile, forced-draft cooling towers. (Credit: EDF/Marc Mourceau)

Gene Editing Spiders To Produce Red Fluorescent Silk

May 21, 2025 by Maya Posch 15 Comments

Regular vs gene-edited spider silk with a fluorescent gene added. (Credit: Santiago-Rivera et al. 2025, Angewandte Chemie)

Continuing the scientific theme of adding fluorescent proteins to everything that moves, this time spiders found themselves at the pointy end of the CRISPR-Cas9 injection needle. In a study by researchers at the University of Bayreuth, common house spiders (Parasteatoda tepidariorum) had a gene inserted for a red fluorescent protein in addition to having an existing gene for eye development disabled. This was the first time that spiders have been subjected to this kind of gene-editing study, mostly due to how fiddly they are to handle as well as their genome duplication characteristics.

In the research paper in Angewandte Chemie the methods and results are detailed, with the knock-out approach of the sine oculis (C1) gene being tried first as a proof of concept. The CRISPR solution was injected into the ovaries of female spiders, whose offspring then carried the mutation. With clear deficiencies in eye development observable in this offspring, the researchers moved on to adding the red fluorescent protein gene with another CRISPR solution, which targets the major ampullate gland where the silk is produced.

Ultimately, this research serves to demonstrate that it is possible to not only study spiders in more depth these days using tools like CRISPR-Cas9, but also that it is possible to customize and study spider silk production.

Fault Analysis Of A 120W Anker GaNPrime Charger

May 21, 2025 by Maya Posch 39 Comments

Taking a break from his usual prodding at suspicious AliExpress USB chargers, [DiodeGoneWild] recently had a gander at what used to be a good USB charger.

The Anker 737 USB charger prior to its autopsy. (Credit: DiodeGoneWild, YouTube) — The Anker 737 USB charger prior to its autopsy.

Before it went completely dead, the Anker 737 GaNPrime USB charger which a viewer sent him was capable of up to 120 Watts combined across its two USB-C and one USB-A outputs. Naturally the charger’s enclosure couldn’t be opened non-destructively, and it turned out to have (soft) potting compound filling up the voids, making it a treat to diagnose. Suffice it to say that these devices are not designed to be repaired.

With it being an autopsy, the unit got broken down into the individual PCBs, with a short detected that eventually got traced down to an IC marked ‘SW3536’, which is one of the ICs that communicates with the connected USB device to negotiate the voltage. With the one IC having shorted, it appears that it rendered the entire charger into an expensive paperweight.

Since the charger was already in pieces, the rest of the circuit and its ICs were also analyzed. Here the gallium nitride (GaN) part was found in the Navitas GaNFast NV6136A FET with integrated gate driver, along with an Infineon CoolGaN IGI60F1414A1L integrated power stage. Unfortunately all of the cool technology was rendered useless by one component developing a short, even if it made for a fascinating look inside one of these very chonky USB chargers.

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