DIY Book Lamp Is A Different Take On The Illuminated Manuscript

July 1, 2025 by Navarre Bartz No comments

People have been coming up with clever ways to bring light to the darkness since we lived in caves, so it’s no surprise we still love finding interesting ways to illuminate our world. [Michael] designed a simple, but beautiful, book lamp that’s easy to assemble yourself.

This build really outshines its origins as an assembly of conductive tape, paper, resistors, LEDs, button cells, and a binder clip. With a printable template for the circuit, this project seems perfect for a makerspace workshop or school science project kids could take home with them. [Michael] walks us through assembling the project in a quick video and even has additional information available for working with conductive tape which makes it super approachable for the beginner.

The slider switch is particularly interesting as it allows you to only turn on the light when the book is open using just conductive tape and paper. We can think of a few other ways you could control this, but they quickly start increasing the part count which makes this particularly elegant. By changing the paper used for the shade or the cover material for the book, you can put a fun spin on the project to match any aesthetic.

If you want to build something a little more complex to light your world, how about a 3D printed Shoji lamp, a color-accurate therapy lamp, or a lamp that can tell you to get back to work.

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In Vivo CAR T Cell Generation For Cancer And Auto-Immune Treatments

July 1, 2025 by Maya Posch 1 Comment

With immunotherapy increasingly making it out of the lab and into hospitals as a viable way to treat serious conditions like cancer, there’s a lot of pressure to optimize these therapies. This is especially true for therapies involving chimeric antigen receptor (CAR) T cells, which so far required a cumbersome process of extracting the patient’s T cells, modifying them ex vivo and returning the now CAR T cells to the patient’s body. After a recently published study, it seems that we may see in vivo CAR T cell therapy become reality, with all the ease of getting a vaccine shot.

We covered CAR T cells previously in the context of a way to prevent T cell exhaustion and making them more effective against certain tumors. This new study (paywalled) by [Theresa L. Hunter] et al. as published in Science demonstrates performing the CAR manipulation in vivo using CD8+ T cell targeting lipid nanoparticles containing mRNA to reprogram these T cells directly.

In rodent and non-human primate studies a clear effect on tumor control was demonstrated, with for auto-immune diseases the related B cells becoming effectively depleted. Although it’s still a long way off from human trials and market approval, this research builds upon the knowledge gained from existing mRNA vaccines, raising hopes that one day auto-immune or cancer therapy could be as simple as getting a cheap, standardized shot.

The 2025 Iberian Peninsula Blackout: From Solar Wobbles To Cascade Failures

June 30, 2025 by Maya Posch 70 Comments

Some Mondays are worse than others, but April 28 2025 was particularly bad for millions of people in Spain and Portugal. Starting just after noon, a number of significant grid oscillations occurred which would worsen over the course of minutes until both countries were plunged into a blackout. After a first substation tripped, in the span of only a few tens of seconds the effects cascaded across the Iberian peninsula as generators, substations, and transmission lines tripped and went offline. Only after the HVDC and AC transmission lines at the Spain-France border tripped did the cascade stop, but it had left practically the entirety of the peninsula without a functioning power grid. The event is estimated to have been the biggest blackout in Europe ever.

Following the blackout, grid operators in the affected regions scrambled to restore power, while the populace tried to make the best of being plummeted suddenly into a pre-electricity era. Yet even as power gradually came back online over the course of about ten hours, the question of what could cause such a complete grid collapse and whether it might happen again remained.

With recently a number of official investigation reports having been published, we have now finally some insight in how a big chunk of the European electrical grid suddenly tipped over.

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Making Optical Glass From Ceran Stovetops

June 28, 2025 by Maya Posch 2 Comments

The Ceran discs, freshly cut from the old stovetop and awaiting polishing. (Credit: Huygens Optics)

Ceran is a name brand for a type of glass ceramic that has a very low coefficient of thermal expansion (CTE). This is useful for stovetops, but it is also a highly desirable property for optical glass. The natural question: Can an old ceramic stovetop be upcycled into something visually striking? This is the topic of the most recent video in [Huygens Optics]’s series on glass ceramics.

Interestingly, by baking sections of the Ceran glass ceramic for 10 minutes at 961 °C, the CTE can be lowered by another five times, from 0.5 ppm / °C to a mere 0.1 ppm / °C. Following baking, you need a lot of grinding and polishing to remove any warping, existing textures, and printing. After polishing with 220 grit by hand for a few minutes, most of these issues were fixed, but for subsequent polishing, you want to use a machine to get the required nanometer-level precision, as well as to survive the six to eight hours of polishing.

Following this final polishing, the discs were ground into mirrors for a Newtonian telescope. This raised a small issue of the Ceran being only 4 mm thick, which requires doubling up two of the discs using a very thin layer of epoxy. After careful drilling, dodging cracked glass, and more polishing, this produced the world’s first ceramic stovetop upcycled into a telescope. We think it was the first, anyway. All that’s left is to coat the discs with a more reflective coating and install them into a telescope frame, but even in their raw state, they show the potential of this kind of material.

If you decide to try this, and you’ve already cut up your stove, you might as well attack some kitchen bowls, too.

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All The Stars, All The Time

June 27, 2025 by Bryan Cockfield 5 Comments

Some of the largest objects in the night sky to view through a telescope are galaxies and supernova remnants, often many times larger in size than the moon but generally much less bright. Even so, they take up a mere fraction of the night sky, with even the largest planets in our solar system only taking up a few arcseconds and stars appearing as point sources. There are more things to look at in the sky than there are telescopes, regardless of size, so it might almost seem like an impossible task to see everything. Yet that’s what this new telescope in Chile aims to do.

The Vera C. Rubin Observatory plans to image the entire sky every few nights over a period lasting for ten years. This will allow astronomers to see the many ways the cosmos change with more data than has ever been available to them. The field of view of the telescope is about 3.5 degrees in diameter, so it needs to move often and quickly in order to take these images. At first glance the telescope looks like any other large, visible light telescope on the tops of the Andes, Mauna Kea, or the Canary Islands. But it has a huge motor to move it, as well as a large sensor which generates a 3200-megapixel image every 30 seconds.

In many ways the observatory’s telescope an imaging technology is only the first part of the project. A number of machine learning algorithms and other software solutions have been created to help astronomers sift through the huge amount of data the telescope is generating and find new irregularities in the data, from asteroids to supernovae. First light for the telescope was this month, June 2025, and some of the first images can be seen here. There have been a number of interesting astronomical observations underway lately even excluding the JWST. Take a look at this solar telescope which uses a new algorithm to take much higher resolution images than ever before.

Earth’s Oxygen Levels And Magnetic Field Strength Show Strong Correlation

June 23, 2025 by Maya Posch 19 Comments

Time series of O2 (blue) and VGADM (red). (Credit: Weijia Kuang, Science Advances, 2025)

In an Earth-sized take on the age-old ‘correlation or causality’ question, researchers have come across a fascinating match between Earth’s magnetic field and its oxygen levels since the Cambrian explosion, about 500 million years ago. The full results by [Weijia Kuang] et al. were published in Science Advances, where the authors speculate that this high correlation between the geomagnetic dipole and oxygen levels as recorded in the Earth’s geological mineral record may be indicative of the Earth’s geological processes affecting the evolution of lifeforms in its biosphere.

As with any such correlation, one has to entertain the notion that said correlation might be spurious or indirectly related before assuming a strong causal link. Here it is for example known already that the solar winds affect the Earth’s atmosphere and with it the geomagnetic field, as more intense solar winds increase the loss of oxygen into space, but this does not affect the strength of the geomagnetic field, just its shape. The question is thus whether there is a mechanism that would affect this field strength and consequently cause the loss of oxygen to the solar winds to spike.

Here the authors suggest that the Earth’s core dynamics – critical to the geomagnetic field – may play a major role, with conceivably the core-mantle interactions over the course of millions of years affecting it. As supercontinents like Pangea formed, broke up and partially reformed again, the impact of this material solidifying and melting could have been the underlying cause of these fluctuations in oxygen and magnetic field strength levels.

Although hard to say at this point in time, it may very well be that this correlation is causal, albeit as symptoms of activity of the Earth’s core and liquid mantle.

Replacing Crude Oil Fractional Distillation With Microporous Polyimine Membranes

June 21, 2025 by Maya Posch 12 Comments

Currently the typical way that crude oil is processed involves a fractional distillation column, in which heated crude oil is separated into the various hydrocarbon compounds using distinct boiling points. This requires the addition of significant thermal energy and is thus fairly energy intensive. A possible alternative has been proposed by [Tae Hoon Lee] et al. with a research article in Science. They adapted membranes used with reverse-osmosis filtration to instead filter crude oil into its constituents, which could enable skipping the heating step and thus save a lot of energy.

The main change that had to be made was to replace the typical polyamide films with polyimine ones, as the former have the tendency to swell up – and thus becomes less effective – when exposed to organic solvents, which includes hydrocarbons. During testing, including with a mixture of naphtha, kerosene and diesel, the polyimine membrane was able to separate these by their molecular size.

It should be noted of course that this is still just small scale lab-testing and the real proof will be in whether it can scale up to the flow rates and endurance required from a replacement for a distillation column. Since this research is funded in part by the fossil fuel industry, one can at least expect that some trial installations will be set up before long, with hopefully positive results.