Miss Beatrice Shilling Saves The Spitfire

January 16, 2018 by Dan Maloney 54 Comments

On a bright spring morning in 1940, the Royal Air Force pilot was in the fight of his life. Strapped into his brand new Supermarine Spitfire, he was locked in mortal combat with a Luftwaffe pilot over the English Channel in the opening days of the Battle of Britain. The Spitfire was behind the Messerschmitt and almost within range to unleash a deadly barrage of rounds from the ~~four~~ eight Browning machine guns in the leading edges of the elliptical wings. With the German plane just below the centerline of the gunsight’s crosshairs, the British pilot pushed the Spit’s lollipop stick forward to dive slightly and rake his rounds across the Bf-109. He felt the tug of the harness on his shoulders keeping him in his seat as the nimble fighter pulled a negative-g dive, and he lined up the fatal shot.

But the powerful V-12 Merlin engine sputtered, black smoke trailing along the fuselage as the engine cut out. Without power, the young pilot watched in horror as the three-bladed propeller wound to a stop. With the cold Channel waters looming in his windscreen, there was no time to restart the engine. The pilot bailed out in the nick of time, watching his beautiful plane cartwheel into the water as he floated down to join it, wondering what had just happened.

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Henrietta Lacks And Immortal Cell Lines

January 9, 2018 by Adam Fabio 80 Comments

In early 1951, a woman named Henrietta Lacks visited the “colored ward” at Johns Hopkins hospital for a painful lump she found on her cervix. She was seen by Dr. Howard W. Jones, who indeed found a tumor growing on the surface of her cervix. He took a tissue sample, which confirmed Henrietta’s worst fears: She had cancer.

The treatment at the time was to irradiate the tumor with radium tubes placed in and around the cervix. The hope was that this would kill the cancerous cells while preserving the healthy tissue. Unbeknownst to Henrietta, a biopsy was taken during her radium procedure. Slivers of her tumor and of healthy cervix cells were cut away. The cancer cells were used as part of a research project. Then something amazing happened: the cancerous cells grew and continued to grow outside of her body.

As Henrietta herself lay dying, the HeLa immortal cell line was born. This cell line has been used in nearly every aspect of medical research since the polio vaccine. Millions owe their lives to it. Yet, Henrietta and her family never gave consent for any of this. Her family was not informed or compensated. In fact, until recently, they didn’t fully grasp exactly how Henrietta’s cells were being used.

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44 Layers Of Katharine Burr Blodgett

January 2, 2018 by Kristina Panos 22 Comments

Whether you realize it or not, Katharine Burr Blodgett has made your life better. If you’ve ever looked through a viewfinder, a telescope, or the windshield of a car, you’ve been face to face with her greatest achievement, non-reflective glass.

Katharine was a surface chemist for General Electric and a visionary engineer who discovered a way to make ordinary glass 99% transparent. Her invention enabled the low-cost production of nearly invisible panes and lenses for everything from picture frames and projectors to eyeglasses and spyglasses.

Katharine’s education and ingenuity along with her place in the zeitgeist led her into other fields throughout her career. When World War II erupted, GE shifted their focus to military applications. Katharine rolled up her sleeves and got down in the scientific trenches with the men of the Research Lab. She invented a method for de-icing airplane wings, engineered better gas masks, and created a more economical oil-based smokescreen. She was a versatile, insightful scientist who gave humanity a clearer view of the universe.

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Barbara McClintock: Against The Genetic Grain

December 28, 2017 by Steven Dufresne 8 Comments

The tale of much of Barbara McClintock’s life is that of the scientist working long hours with a microscope seeking to solve mysteries. The mystery she spent most of her career trying to solve was how all cells in an organism can contain the same DNA, and yet divide to produce cells serving different functions; basically how cells differentiate. And for that, she got a Nobel prize all to herself, which is no small feat either.

Becoming a Scientist

Human chromosomes, long strands of DNA by Steffen Dietzel CC BY-SA 3.0

McClintock was born on June 16, 1902, in Hartford, Connecticut, USA. From age three until beginning school, she lived with her aunt in Brooklyn, New York while her father strove financially to start up a medical practice. She was a solitary and independent-minded child, a trait she later called her “capacity to be alone”.

In 1919, she began her studies at Cornell’s College of Agriculture and took her first course in genetics in 1921. A year later, due to the interest she showed in genetics, she was invited to take the graduate genetics course at Cornell. It was here that she became interested in the new field of cytogenetics, specifically of maize or corn. Cytogenetics studies how the chromosomes relate to cell behavior, particularly during cell division. Chromosomes are the long strands of DNA within the nucleus of every cell and shown here in the photo at a time when they are condensed, or coiled up.

While still at Cornell she developed a number of methods for visualizing and characterizing maize which ended up in textbooks. She also became the first to describe the morphology of the ten maize chromosomes, basically their form and structural relationships, which then allowed her to discover more about the chromosomes. One of her colleagues observed that ten of the seventeen significant advances made in the field at Cornell between 1929 and 1935 were hers. This was only the first step in what would be the remarkable career of a very well respected scientist.

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Jerri Nielsen: Surviving The Last Place On Earth

December 19, 2017 by Dan Maloney 45 Comments

There may be no place on Earth less visited by humans than the South Pole. Despite a permanent research base with buildings clustered about the pole and active scientific programs, comparatively few people have made the arduous journey there. From October to February, up to 200 people may be stationed at the Amundsen-Scott South Pole Station for the Antarctic summer, and tourists checking an item off their bucket lists come and go. But by March, when the sun dips below the horizon for the next six months, almost everyone has cleared out, except for a couple of dozen “winter-overs” who settle in to maintain the station, carry on research, and survive the worst weather Mother Nature brews up anywhere on the planet.

To be a winter-over means accepting the fact that whatever happens, once that last plane leaves, you’re on your own for eight months. Such isolation and self-reliance require special people, and Dr. Jerri Nielsen was one who took the challenge. But as she and the other winter-overs watched the last plane leave the Pole in 1998 and prepared for the ritual first-night screening of John Carpenter’s The Thing, she had no way of knowing what she would have to do to survive the cancer that was even then growing inside her.

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Maria Mitchell: The First Woman Astronomy Professor

December 12, 2017 by Dan Maloney 11 Comments

On an October night in 1847, a telescope on the roof of the Pacific National Bank building on Nantucket Island was trained onto the deep black sky. At the eyepiece was an accomplished amateur astronomer on the verge of a major discovery — a new comet, one not recorded in any almanac. The comet, which we today know by the dry designator C/1847 T1, is more popularly known as “Miss Mitchell’s Comet,” named after its discoverer, a 29-year old woman named Maria Mitchell. The discovery of the comet would, after a fashion, secure her reputation as a scholar and a scientist, but it was hardly her first success, and it wouldn’t be her last by a long shot.

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Disrupting The Computer Industry Before It Existed: Rear Admiral Grace Hopper

December 5, 2017 by Christian Trapp 32 Comments

The feature of being easier to write than assembly is often seen as the biggest advantage of high-level programming languages. The other benefit that comes with them is portability. With high-level languages, algorithms can be developed independently from the underlying hardware. This allows software to live on once the hardware becomes obsolete.

The compiler was a concept that was met with resistance when it was first introduced. This was at a time when computers were custom-built machines bearing individual names like ENIAC, UNIVAC and Mark I. A time when the global demand for computers was estimated to be around five units by the CEO of IBM. In this scenario, it took a visionary to foresee a future where the number of computers would outgrow the number of programmers and hardware would evolve so much faster than software that a compiler would make sense. One visionary was [Grace Hopper].

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