Mixing synthetic blood

The Challenges Of Finding A Substitute For Human Blood

Throughout history, the human body has been the subject of endless scrutiny and wonder. Many puzzled over the function of all these organs and fluids found inside. This included the purpose of blood, which saw itself alternately disregarded as being merely for ‘cooling the body’, to being responsible for regulating the body’s humors, leading to the practice of bloodletting and other questionable remedies. As medical science progressed, however, we came to quite a different perspective.

Simply put, our circulatory system and the blood inside it, is what allows us large, multi-celled organisms to exist. It carries oxygen and nutrients to cells, while enabling the removal of waste products as well as an easy path for the cells that make up our immune system. Our blood and the tissues involved with it are crucial to a healthy existence. This is something which becomes painfully clear when we talk about injuries and surgeries that involve severe blood loss.

While the practice of blood transfusions from donated blood has made a tremendous difference here, it’s not always easy to keep every single type of blood stocked, especially not in remote hospitals, in an ambulance, or in the midst of a war zone. Here the use of artificial blood — free from complicated storage requirements and the need to balance blood types — could be revolutionary and save countless lives, including those whose religion forbids the transfusion of human blood.

Although a lot of progress has been made in this field, with a limited number of practical products, it’s nevertheless proving to be a challenge to hit upon a replacement that ticks all of the boxes needed to make it generic and safe.

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Microsoft’s Minimal Mouse May Maximize Masochism

So it seems that Microsoft has a patent in process for a folding mouse.  It looks a whole lot like their Arc mouse, which is quite thin and already goes from curved to flat. But that’s apparently not good enough for Microsoft, who says mice in general are bulky and cumbersome to travel with. On the bright side, they do acknowledge the total lack of ergonomics in those tiny travel mice.

Microsoft filed this patent in March of 2021 and it was published in early November. The patent describes the use of an expandable shell on the top with these kerf cuts in the long sides like those used to bend wood — this is where the flexibility comes in. The patent also mentions a motion tracker, haptic feedback, and a wireless charging coil. Now remember, there’s no guarantee of this ever actually happening, and there was no comment from Microsoft about whether it will become a real rodent someday.

And now, the rant. Microsoft considers this mouse, which again is essentially an updated Arc that folds in half, to be ergonomic. Full disclosure: I’ve never used an Arc mouse. But I respectfully disagree with this assessment and believe that people should not prioritize portability when it comes to peripherals, especially those that are so small to begin with. Like, what’s the use? And by the way, isn’t anyone this concerned with portability just using the touch pad or steering stick on their laptop anyway?

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TTL And CMOS Logic ICs: The Building Blocks Of A Revolution

When starting a new electronics project today, one of the first things that we tend to do is pick the integrated circuits that make up the core of the design. This can be anything from a microcontroller and various controller ICs to a sprinkling of MOSFETs, opamps, and possibly some 7400- or 4000-series logic ICs to tie things together. Yet it hasn’t been that long since this level of high integration and miniaturization was firmly in the realm of science-fiction, with even NORBIT modules seeming futuristic.

Starting with the construction of the first point-contact transistor in 1947 and the bipolar junction transistor (BJT) in 1948 at Bell Labs, the electronics world would soon see the beginning of its biggest transformation to that point. Yet due to the interesting geopolitical circumstances of the 20th century, this led to a fascinating situation of parallel development, blatant copying of designs, and one of the most fascinating stories in technology history on both sides of the Iron Curtain. Continue reading “TTL And CMOS Logic ICs: The Building Blocks Of A Revolution”

Mr Fusion powering a vehicle

Motorsports Are Turning To Alternative Fuels

As the world grapples with the issue of climate change, there’s a huge pressure to move transport away from carbon-based fuels across the board. Whether it’s turning to electric cars for commuting or improving the efficiency of the trucking industry, there’s much work to be done.

It’s a drop in the ocean in comparison, but the world of motorsports has not escaped attention when it comes to cleaning up its act. As a result, many motorsports are beginning to explore the use of alternative fuels in order to reduce their impact on the environment.

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Ask Hackaday: Why Don’t Automakers Make Their Own EV Batteries?

Sales of electric vehicles continue to climb, topping three million cars worldwide last year. All these electric cars need batteries, of course, which means demand for rechargeable cells is through the roof.

All those cells have to come from somewhere, of course, and many are surprised to learn that automakers don’t manufacture EV batteries themselves. Instead, they’re typically sourced from outside suppliers. Today, you get to Ask Hackaday: why aren’t EV batteries manufactured by the automakers themselves? Continue reading “Ask Hackaday: Why Don’t Automakers Make Their Own EV Batteries?”

What’s The Deal With UEFI?

It seems like there are two camps, the small group of people who care about UEFI and everyone else who doesn’t really notice or care as long as their computer works. So let’s talk about what UEFI is, how it came to be, what it’s suitable for, and why you should (or shouldn’t) care.

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Laptop keyboard with strange characters on the keys

But Think Of The (World Wide) Users!

History is full of stories about technology that makes sense to the designer but doesn’t really fit the needs of the users. Take cake mixes. In 1929, a man named Duff realized that he could capitalize on surplus flour and molasses and created a cake mix. You simply added water to the dry mix and baked it to create a delicious cake. After World War II General Mills and Pillsbury also wanted to sell more flour so they started making cakes. But sales leveled out. A psychologist who was a pioneer in focus groups named Dichter had the answer: bakers didn’t feel like they were contributing to the creation of the cake. To get more emotional investment, the cake mixes would need to have real eggs added in. Actually, Duff had noticed the same thing in his 1933 patent.

It is easy to imagine a bunch of food… scientists? Engineers? Designers?… whatever a person inventing flour mixes in the 1930s was called… sitting around thinking that making a mix that only requires water is a great thing. But the bakers didn’t like it. How often do we fail to account for users?

From Cake Mix to Tech

Apple has made a business of this. Most of us don’t mind things like arcane commands and control key combinations, but the wider pool of global computer users don’t like those things. As the world continues to virtually shrink, we often find our users are people from different lands and cultures who speak different languages. It is, after all, the world wide web. This requires us to think even harder about our users and their particular likes, dislikes, and customs.

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