Turning PET Plastic Into Paracetamol With This One Bacterial Trick

July 8, 2025 by 30 Comments

Over the course of evolution microorganisms have evolved pathways to break down many materials. The challenge with the many materials that we humans have created over just the past decades is that we cannot wait for evolution to catch up, ergo we have to develop such pathways ourselves. One such example is demonstrated by [Nick W. Johnson] et al. with a recent study in Nature Chemistry that explicitly targets PET plastic, which is very commonly used in plastic bottles.

The researchers modified regular E. coli bacteria to use PET plastic as an input via Lossen rearrangement, which converts hydroxamate esters to isocyanates, with at the end of the pathway para-aminobenzoate (PABA)  resulting, which using biosynthesis created paracetamol, the active ingredient in Tylenol. This new pathway is also completely harmless to the bacterium, which is always a potential pitfall with this kind of biological pathway engineering.

In addition to this offering a potential way to convert PET bottles into paracetamol, the researchers note that their findings could be very beneficial to studies targeting other ‘waste’ products from biological pathways.

Thanks to [DjBiohazard] for the tip.

The Hackaday Summer Reading List: No AI Involvement, Guaranteed

July 7, 2025 by 48 Comments

If you have any empathy at all for those of us in the journalistic profession, have some pity for the poor editor at the Chicago Sun-Times, who let through an AI-generated summer reading list made up of novels which didn’t exist.  The fake works all had real authors and thus looked plausible, thus we expect that librarians and booksellers throughout the paper’s distribution area were left scratching their heads as to why they’re not in the catalogue.

Here at Hackaday we’re refreshingly meat-based, so with a guarantee of no machine involvement, we’d like to present our own summer reading list. They’re none of them new works but we think you’ll find them as entertaining, informative, or downright useful as we did when we read them. What are you reading this summer? Continue reading “The Hackaday Summer Reading List: No AI Involvement, Guaranteed” →

CIS-4 Is A Monkish Clock Inside A Ceiling Lamp

July 4, 2025 by 2 Comments

It’s always clock time at Hackaday, and this time we have an interesting hack of a clock by [danjovic]– the CIS4, a Cistercian digital clock.

The Cistertians, in case you weren’t paying close attention to European holy orders during the 13th to 15th centuries were the group of monks you’d most likely have found us in. They were the hackers of the middle ages, establishing monestaries across western Europe that were chock full of hacks– including their own numeral system. Cistercian numerals were much more efficient (in spaces and penstrokes) than the Roman numerals they replaced, and even the “Arabic” numerals that replaced them. A single glyph could record anything from 1 to 9,999. (The Europeans hadn’t yet cottoned on to zero.)

The Cistertian glyphs reduced to a 4×4 display.

Depending how you wanted to count time, a single glyph could be used; it looks like [danjovic] is using the thousands and hundreds portions of the glyph for hours and the tens and ones for minutes. This is all accomplished with a 4×4 neopixel matrix, run by an Attiny85 Digispark with a DS3231 RTC module keeping time. A slight simplification is required to reduce the glyphs to 4×4, but we don’t think the monks would mind. For those of us who don’t wear tonsures, an easy read mode scrolls the time in Arabic numerals. (Which still aren’t super easy,with only 4×4 LEDs to display them. See the demo video embedded below and try and guess the time.)

One nice quality of life feature is an LDR for ambient light detection, to automatically adjust the neopixels’ brightness. The hackiest part, which we thought was really clever, is the enclosure: it’s a cheap LED ceiling light. This provides a diffuser, housing and mounting hardware with decent design for no effort. A 3D-printed mask sits between the diffuser and the LEDs and doubles as a PCB holder. All very elegant.

[danjovic] did include a buzzer in the design, but does say if its been programed to sound off for matins, nones and vespers. In any case, at least it’s easier to read than his binary-coded-octal clock that we featured a few years back. This isn’t our first look at this number system,so evidently people can read them with practice.

Have you made or seen a cool clock? Send us a tip. We always have time for clocks. Continue reading “CIS-4 Is A Monkish Clock Inside A Ceiling Lamp” →

PS1 logo on the top screen of a white DS

Running An Entire PS1 Emulator In A DS Cartridge

July 4, 2025 by 8 Comments

Gaming on a Nintendo DS can bring back great memories of long car trips from the past. But looking back, we remember wishing to play more than the DS could ever hope to handle. [fami] looks into the SuperCard DSTWO in her recent video, a solution to our past sorrows.

Able to play anything from the very games designed for the DS to emulated PS1 games, the DSTWO is more than capable of surpassing the abilities of the DS itself. More impressively, all games are run directly from the cartridge itself rather than on the DS’s hardware. While this emulated console within a handheld is impressive, it is far from simple to get running.

The DSTWO runs with an Ingenic JZ4732 as the CPU, completely different from any native architecture of the DS. Pair this with the unhelpful SDK made for the cartridge, and the aging hardware is held together by the community development behind any improvements. This is aided by the CPU similarities of another widely modded game console, the Dingoo A320.

When not having a fit, and after going through hours of troubleshooting, you might find the DSTWO running a game of SimCity 2000 or even Spyro the Dragon inside a DS. Even with the difficulties of use, the fact that these games run at all is impressive. If you want to try the DSTWO emulation yourself, check out the forums.

This is far from the only example of extreme care going into emulation. Here at Hackaday, we have covered similarly impressive projects such as this completely DIY handheld made for any retro game emulation you throw at it.

Continue reading “Running An Entire PS1 Emulator In A DS Cartridge” →

Back To The Future, 40 Years Old, Looks Like The Past

July 3, 2025 by 81 Comments

Great Scott! If my calculations are correct, when this baby hits 88 miles per hour, you’re gonna see some serious shit. — Doc Brown

On this day, forty years ago, July 3rd, 1985 the movie Back to the Future was released. While not as fundamental as Hackers or realistic as Sneakers, this movie worked its way into our pantheon. We thought it would be appropriate to commemorate this element of hacker culture on this day, its forty year anniversary.

If you just never got around to watching it, or if it has been a few decades since you did, then you might not recall that the movie is set in two periods. It opens in 1985 and then goes back to 1955. Most of the movie is set in 1955 with Marty trying to get back to 1985 — “back to the future”. The movie celebrates the advanced technology and fashions of 1985 and is all about how silly the technology and fashions of 1955 are as compared with the advancements of 1985. But now it’s the far future, the year 2025, and we thought we might take a look at some of the technology that was enchanting in 1985 but that turned out to be obsolete in “the future”, forty years on. Continue reading “Back To The Future, 40 Years Old, Looks Like The Past” →

The Rise And The Fall Of The Mail Chute

June 25, 2025 by 17 Comments

As the Industrial Age took the world by storm, city centers became burgeoning hubs of commerce and activity. New offices and apartments were built higher and higher as density increased and skylines grew ever upwards. One could live and work at height, but this created a simple inconvenience—if you wanted to send any mail, you had to go all the way down to ground level.

In true American fashion, this minor inconvenience would not be allowed to stand. A simple invention would solve the problem, only to later fall out of vogue as technology and safety standards moved on. Today, we explore the rise and fall of the humble mail chute.

Continue reading “The Rise And The Fall Of The Mail Chute” →

A map of the United States showing a series of interconnected lines in white, red, orange, yellow, and green to denote fiber optic and electrical transmission lines. Dots of white, orange, and yellow denote the location of the data centers relative to nearby metropolitan centers.

NREL Maps Out US Data Infrastructure

June 24, 2025 by 13 Comments

Spending time as wee hackers perusing the family atlas taught us an appreciation for a good map, and [Billy Roberts], a cartographer at NREL, has served up a doozy with a map of the data center infrastructure in the United States. [via LinkedIn]

Fiber optic lines, electrical transmission capacity, and the data centers themselves are all here. Each data center is a dot with its size indicating how power hungry it is and its approximate location relative to nearby metropolitan areas. Color coding of these dots also helps us understand if the data center is already in operation (yellow), under construction (orange), or proposed (white).

Also of interest to renewable energy nerds would be the presence of some high voltage DC transmission lines on the map which may be the future of electrical transmission. As the exact location of fiber optic lines and other data making up the map are either proprietary, sensitive, or both, the map is only available as a static image.

If you’re itching to learn more about maps, how about exploring why they don’t quite match reality, how to bring OpenStreetMap data into Minecraft, or see how the live map in a 1960s airliner worked.