Our bodies are not like LEGO blocks or computers because we cannot swap out our parts in the living room while watching television. Organ transplants and cosmetic surgery are currently our options for upgrades, repairs, and augments, but post-transplant therapy can be a lifelong commitment because of rejection. Elective surgery costs more than a NIB Millenium Falcon LEGO set. Laboratories have been improving the processes and associated treatments for decades but experimental labs and even home laboratories are getting in on the action as some creative minds take the stage. These folks aren’t performing surgeries, but they are expanding what is possible to for people to do and learn without a medical license.
One promising gateway to human building blocks is the decellularization and recellularization of organic material. Commercial scaffolds exist but they are expensive, so the average tinkerer isn’t going to be buying a few to play with over a holiday weekend.
Let’s explore what all this means. When something is decellularized, it means that the cells are removed, but the structure holding the cells in place remains. Recellularizing is the process where new cells are grown in that area. Decellularizing is like stripping a Hilton hotel down to the girders. The remaining structures are the ECM or the Extra Cellular Matrix, usually referred to as scaffolding. The structure has a shape but no functionality, like a stripped hotel. The scaffolding can be repopulated with new cells in the same way that our gutted hotel can be rebuilt as a factory, office building, or a hospital.
Continue reading “Decellularization: Apples To Earlobes”
Positive reinforcement is the process of getting someone to understand their actions result in a reward. Children get a sweet treat when they pick up all their toys and older ones might get some cash for mowing the lawn. From the perspective of the treat-giver, this is like turning treats into work. A Dutch startup wants to teach the crow population to pick up cigarette butts in exchange for bird treats.
The whole Corvidae family of birds is highly intelligent so it shouldn’t be a problem training them that they will get a reward for depositing something the Hominidae family regularly throw on the street where the birds live. This idea is in turn an evolution of the open-source Crow Box.
For some, leveraging the intelligence of animals is more appealing than programming drones which could do the same thing. A vision system mixed with a drone and a manipulator could fulfull the same function but animals are self-repairing and autonomous without our code. The irony of this project is that, although it’s probably fairly easy to train crows to recognize cigarette butts, the implementation hinges on having a vision system that can recognize the butts in order to properly train the crows in the first place.
If we had the time to train crows, it would definitely be to poop on cars that don’t signal for turns. Maybe some of these winged devices can be programmed to recognize lapses in traffic laws in exchange for some electrons.
Thank you, [jo_elektro], for the tip.
[Eric] and [Shirin] have a dog called [Pickles], who is the kind of animal that if you are a dog lover you will secretly covet. They evidently dote upon [Pickles], but face the problem that they can’t always be at home to express their appreciation of him. But rather than abandon him entirely, they’ve applied technology to the problem. [Eric] has built an Internet-connected dog treat dispenser, through which they can dispense treats, and watch the lucky mutt wolfing them down.
The body of the machine has been made with lasercut acrylic, and the dispenser mechanism is a rotating hopper driven by a stepper motor. The whole thing — in all its transparent glory — is controlled through a Raspberry Pi, which plays a sound clip of [Shirin] calling [Pickles] for his treat, records his dining enjoyment with its camera, and emails the result to his owners. Behind the scenes it hosts an MQTT server, which can be triggered via an iPhone app, Alexa, or the adafruit.io site. Imagine for a moment: “Alexa, feed my dog!”. It has a ring to it.
He makes the point that this machine is not simply limited to dispensing treats, it could be used to engage [Pickles] in more activities. He hints at a future project involving a ball throwing device (have you ever seen such joy from a dog). There’s no substitute for being there with your dog, but maybe with this device they can make their dog’s life a little less of, well, a dog’s life.
You can see the machine in action in the video we’ve posted below the break.
Continue reading “The Internet Connected Dog Treat Machine”
Until the industrial revolution, humans made use of animals to make our labor easier. This is still seen in some niche areas, like how no machine yet has been invented that’s as good at sniffing out truffles as pigs are. [William] has hearkened back to humanity’s earlier roots, but in a more modern twist has made something of a general purpose dog that could feasibly do any work imaginable. Now his dog is remote-controlled.
[William] accomplished the monumental task in a literally cartoonish fashion using the old trope of hanging a hot dog in front of something’s face to get them to chase it. The attachment point was fitted with a remote control receiver and an actuator to get the hanging hot dog to dangle a little bit more to the dog’s right or left, depending on where the “operator” wants the dog to go. [William]’s bulldog seems to be a pretty good sport about everything and isn’t any worse for wear either.
Believe it or not, there has been some actual research done into remote controlling animals, although so far it’s limited to remote-controlled cockroaches. We like the simplicity of the remote-controlled dog, though, but don’t expect to see these rigs replacing leashes anytime soon!
Continue reading “Remote Controlling A Dog”
We hear a lot about drone surveillance, drone package delivery, drone this, and drone that. Honestly, though, the best use of drones has been taking cool aerial videos and posting them online. Until now.
The US Fish and Wildlife Service plans to cover acres upon acres of prairie-dog habitat with vaccine-laced, peanut-butter coated M&Ms. The snacks also include a dye that will show up in the whiskers of prairie dogs that take the bait, allowing scientists to assess the efficacy of the program. And this is all in the name of saving endangered black-footed ferrets which share burrows with the prairie dogs. It seems they were getting the plague from the prairie dogs.
The quads are outfitted with a “glorified gumball machine” that spreads the vaccine tidbits around. Why a quad? They can cover more space with less disruption to the animals’ habitat. That’s a great application in our book.
But if you think this is a case of the USF&WS showing outrageous innovation, consider the way rabies was all but eliminated in Europe: throwing hundreds of thousands of vaccine-doped chicken heads out of helicopters across France, Switzerland, and Germany. You couldn’t make this up.
(Via [Popular Science], where the title is even more clickbaity than ours. Get it? “Clickbait”?)
Headline image: US Fish and Wildlife Service Mountain-Prairie
Cats do what they want, which rarely coincides with what their owner wants them to do. In [Dumitru]’s case, his girlfriend’s cat [Pufu] tended to make it outside into the cold more often than desired. Rather than settle with the normal bell which gets obnoxious even when the cat isn’t misbehaving, he decided to put together a custom Cat Finding collar. He used a PIC microcontroller as the brains, and temperature and light sensors to decide whether the cat had snuck into the cold, dark night. Once the cat has been marked as being outside, a buzzer and LED are set to go off at regular intervals until returned into the safety of the indoors.
[Dumitru]’s website along with his YouTube videos are in Romanian, though the schematics and source code provided speak for themselves. He does a wonderful job walking through the entire design process, including time spend in the IDE as well as EAGLE designing the board. YouTube has managed to subtitle the majority of the details, but we imagine this post will be a real treat to any Romanian speaking hobbyists out there. Be sure to catch both videos after the break.
Continue reading “Out Engineering A Sneaky Cat”