Self-Driving Laboratories Do Research On Autopilot

September 29, 2022 by Lewin Day 16 Comments

Scientific research is a messy business. The road to learning new things and making discoveries is paved with hard labor, tough thinking, and plenty of dead ends. It’s a time-consuming, expensive endeavor, and for every success, there are thousands upon thousands of failures.

It’s a process so inefficient, you would think someone would have automated it already. The concept of the self-driving laboratory aims to do exactly that, and could revolutionize materials research in particular.

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Mining And Refining: Sulfur

September 28, 2022 by Dan Maloney 23 Comments

When you think of the periodic table, some elements just have a vibe to them that’s completely unscientific, but nonetheless undeniable. Precious metals like gold and silver are obvious examples, associated as they always have been with the wealth of kings. Copper and iron are sturdy working-class metals, each worthy of having entire ages of human industry named after them, with silicon now forming the backbone of our current Information Age. Carbon builds up the chemistry of life itself and fuels almost all human endeavors, and none of us would get very far without oxygen.

But what about sulfur? Nobody seems to think much about poor sulfur, and when they do it tends to be derogatory. Sulfur puts the stink in rotten eggs, threatens us when it spews from the mouths of volcanoes, and can become a deadly threat when used to make gunpowder. Sulfur seems like something more associated with the noxious processes and bleak factories of the early Industrial Revolution, not a component of our modern, high-technology world.

And yet despite its malodorous and low-tech reputation, there are actually few industrial processes that don’t depend on massive amounts of sulfur in some way. Sulfur is a critical ingredient in processes that form the foundation of almost all industry, so its production is usually a matter of national and economic security, which is odd considering that nearly all the sulfur we use is recovered from the waste of other industrial processes.

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Cursing The Curse Of Cursive

September 27, 2022 by Kristina Panos 114 Comments

Unlike probably most people, I enjoy the act of writing by hand — but I’ve always disliked signing my name. Why is that? I think it’s because signatures are supposed to be in cursive, or else they don’t count. At least, that’s what I was taught growing up. (And I’m really not that old, I swear!)

Having the exact same name as my mother meant that it was important to adolescent me to be different, and that included making sure our signatures looked nothing alike. Whereas her gentle, looping hand spoke to her sensitive and friendly nature, my heavy-handed block print was just another way of letting out my teen angst. Sometime in the last couple of decades, my signature became K-squiggle P-squiggle, which is really just a sped-up, screw-you version of my modern handwriting, which is a combination of print and cursive.

D’Nealian print. Notice the ‘monkey tails’ on every possible lowercase letter.

D’Nealian cursive. Notice the stroke order and the ridiculous capital Q.

But let’s back up a bit. I started learning to write in kindergarten, but that of course was in script, with separate letters. Me and my fellow Xennial zeigeistians learned a specific printing method called D’Nealian, which was designed to ease the transition from printing to cursive with its curly tails on every letter.

We practiced our D’Nealian (So fancy! So grown-up!) on something called Zaner-Bloser paper, which is still used today, and by probably second grade were making that transition from easy Zorro-like lowercase Zs to the quite mature-looking double-squiggle of the cursive version. It was as though our handwriting was moving from day to night, changing and moving as fast as we were. You’d think we would have appreciated learning a way of writing that was more like us — a blur of activity, everything connected, an oddly-modular alphabet that was supposed to serve us well in adulthood. But we didn’t. We hated it. And you probably did, too.

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Smart Pills Can Tell Your Doctor That You’ve Taken Them

September 26, 2022 by Lewin Day 50 Comments

We have many kinds of pills available these days to treat all kinds of different disorders. Of course, the problem with pills is that they don’t work if you don’t take them. Even Worse, for some medicines, missing a dose can cause all kinds of undesirable withdrawl effects and set back a patient’s treatment.

Smart pills aim to fix this problem with a simple monitoring solution that can tell when a patient has taken their medication. They’re now publicly available and authorized for use, so let’s look at how they work.

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Floppy Disk Sales Are Higher-Density Than You Might Think

September 21, 2022 by Kristina Panos 52 Comments

Floppies may be big in Japan, but nostalgic and/or needful Stateside floppy enthusiasts needn’t fret — just ~~use AOL keyword~~ point that browser toward floppydisk.com. There, you can buy new floppies of all sizes, both new and old, recycle your disks, or send them in to get all that precious vintage stuff transferred off of them.

That delightfully Web 1.0 site is owned by Tom Persky, who fancies himself the ‘last man standing in the floppy disk business’. Who are we to argue? By the way, Tom has owned that address since approximately 1990 — evidently that’s when a cyber-squatter offered up the domain for $1,000, and although Tom scoffed at paying so much as $1 for any URL, his wife got the checkbook out, and he has had her to thank for it ever since.

My business, which used to be 90% CD and DVD duplication, is now 90% selling blank floppy disks. It’s shocking to me. — Tom Persky

In the course of writing a book all about yours-truly’s favorite less-than-rigid medium, authors Niek Hilkmann and Thomas Walskaar sat down to talk with Tom about what it’s like to basically sell buggy whips in the age of the electric car.

Tom also owns diskduper.com, which is where he got his start with floppies — by duplicating them. In the 80s and 90s, being in this business was a bit like cranking out legal tender in the basement. As time wore on and more companies stopped selling floppies or simply went under, the focus of Tom’s company shifted away from duplication and toward sales. Whereas the business was once 90% duplication and 10% floppy sales, in 2022, those percentages have flopped places, if you will.

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IGY: The Year We All Got Along

September 20, 2022 by Al Williams 24 Comments

If you are a Steely Dan fan, you might know the Donald Fagen song, “IGY.” In it, Fagen sings about a rosy future with high-speed undersea rail, solar power, giant computers making life better, and spandex jackets. Since that song was on the 1982 album Nightfly, it is already too old for some people to remember, but the title goes back even further: the International Geophysical Year which was actually a little longer than a year in 1957 and 1958. The year was a concerted effort by 67 countries to further mankind’s knowledge of the Earth. It was successful, and was big news in its day, although not much remembered now.

The real origin dates back to even earlier. In 1882 and 1932 there were International Polar Years dedicated to researching the polar regions of the Earth. In a way, it makes sense to do this. Why should 60 or more countries each mount difficult, dangerous, and expensive expeditions to such a hostile environment? However, instead of a third polar year, James Van Allen (who has a famous belt) and some other scientists felt that advances in many fields made it the right time to study geophysics. From the scientific point of view, the IGY coincided with the solar activity cycle maximum. But there were other forces at play, too.

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New Parkinson’s Test Smells Success

September 14, 2022 by Lewin Day 38 Comments

Parkinson’s disease affects millions of people all over the world. The degenerative condition causes characteristic tremors, trouble walking, and often comes with complications including dementia, depression, and anxiety.

One of the major challenges around Parkinson’s disease involves diagnosis. There’s no single, commonly-available test that can confirm or rule out the disease. It’s can cause particular frustration as the disease is most treatable in its early stages.

That may soon change, however. One woman identified that she seemingly had the ability to “smell” the disease in those affected, and is now working with scientists to develop a test for the condition.

Follow Your Nose

The human sense of smell, by and large, isn’t particularly impressive. It helps us enjoy the scent of fresh bread baking in an oven, or the aroma of freshly cut grass. However, as a tool for inspecting and learning about the world around us, it really comes up short.

Some of us, though, are more capable in the olfactory department than others. Joy Milne from Perth, Scotland, is one such person. She happened to detected a change in her partner’s characteristic smell, one day, and twelve years later, they were diagnosed with Parkinson’s disease.

The idea that someone could “smell” a difference with people with Parkinson’s disease is an easy one to test. When Milne eventually put the idea together that the different smell she noticed was perhaps related to her husbands condition, she quickly drew the interest of scientists. With the aid of her partner, a former doctor, she teamed up with researchers Dr. Tilo Kunath and Professor Perdita Barran to investigate further. Continue reading “New Parkinson’s Test Smells Success” →