Once you’ve built your own X-ray machine to take 2D images of the insides of stuff, there’s really only one logical next step: building your own computed tomography (CT) scanner to get 3D reconstructions instead. That’s exactly what [Fran Piernas] has done, and documented over on hackaday.io. While the original X-ray machine build dealt with scary hardware stuff such as high voltage and ionizing radiation, this time it’s the turn of scary mathematics like inverse radon transforms.
The original build, which we wrote about in December, uses a commercial dental X-ray tube and a home-made 65 kV power supply to send X-rays through objects. Transmitted X-rays are viewed using an intensifying screen that converts the rays to visible light. The result is a 2D image similar to that we’re all familiar with.
To create a 3D reconstruction of an object, you need a number of X-ray images taken from different angles. If you’ve ever been unlucky enough to need a medical CT scan, you’ll remember staying motionless in the tunnel while the X-ray apparatus rotated around you. In this build, [Fran] rotates the object instead, using a motor that may have once been part of a microwave oven (one of those “mystery motors” we all have laying around). The required sequence of images is simply obtained by recording video of the X-ray screen while the motor rotates the object.
We all know CERN as that cool place where physicists play with massive, superconducting rings to smash atoms and subatomic particles to uncover secrets of matter in the Universe. To achieve this aim, they need to do a ton of research in other areas, such as development of special particle detectors.
While such developments are essential to the core research needs of the Centre, they also lead to spinoff applications for the benefit of society at large. One such outcome has been the Medipix Collaborations – a family of read-out chips for particle imaging and detection that can count single photons, allowing X-rays and gamma rays to be converted to electrical signals. It may not be possible for us hackers to get our hands on these esoteric sensors, but these devices are pretty interesting and deserve a closer look. Medipix sensors work like a camera, detecting and counting each individual particle hitting the pixels when its electronic shutter is open. This enables high-resolution, high-contrast, noise hit free images – making it unique for imaging applications.
Some months back, CERN announced the first 3D color X-ray of a human made possible using the Medipix devices. The result is a high-resolution, 3D, color image of not just living structures like bones, muscular tissues and vessels, but metal objects too like the wrist watch, seen in the accompanying photograph. The Medipix sensors have been in development since the 1990’s and are presently in their 4th “generation”. Each chip consists of a top semiconducting sensor array, made from gallium arsenide or cadmium telluride. The charge collected by each pixel is transported to the CMOS ASIC electronics via “bump bonds”. The integration is vertical, with each sensing pixel connected via the bump bond to an analog section followed by a digital processing layer. Earlier versions were limited, by technology, in their tiling ability for creating larger matrices of multiple sensors. They could be abutted on three sides only, with the fourth being used for on-chip peripheral logic and wire-bond pads that permit electronic read-out. The latest Medipix4 Collaboration, still under some development, eliminates this short coming. Through-silicon-via (TSV) technology provides the possibility of reading the chips through copper-filled holes that bring the signals from the front side of the chip to its rear. All communication with the pixel matrix flows through the rear of the chip – the peripheral logic and control elements are integrated inside the pixel matrix.
The Analog front end consists of a pre-amplifier followed by a window discriminator which has upper and lower threshold levels. The discriminator has four bits for threshold adjustment as well as polarity sensing. This allows the capture window to be precisely set. The rest of the digital electronics – multiplexers, shift registers, shutter and logic control – helps extract the data.
Further development of the Medipix (Tech Brief, PDF) devices led to a separate version called Timepix (Tech Brief, PDF). These new devices, besides being able to count photons, are capable of two additional modes. The first mode records “Time-Over-Threshold”, providing rough analog information about the energy of the photon. It does this by counting clock pulses for the duration when the signal stays above the discrimination levels. The other mode, “Time of Arrival”, measures arrival time of the first particle to impinge on the pixel. The counters record time between a trigger and detection of radiation quanta with energy above the discrimination level, allowing time-of-flight applications in imaging.
Besides medical imaging, the devices have applications in space, material analysis, education and of course, high energy physics. Hopefully, in a few years, hackers will lay their hands on these interesting devices and we can get to know them better. At the moment, the Medipix website has some more details and data sheets if you would like to dig deeper. For an overview on the development of such single photon detectors, check out this presentation from CERN – “Single X-Ray Photon Counting Systems: Existing Systems, Systems Under Development And Future Trends” (PDF).
David Mills is as a research scientist at the cutting edge of medical imaging. His work doesn’t involve the scanners you might find yourself being thrust into in a hospital should you be unfortunate enough to injure yourself. He’s working with a higher grade of equipment, he pushes the boundaries of the art with much smaller, very high resolution CT scanners for research at a university dental school.
He’s also a friend of Hackaday and we were excited for his talk on interesting uses for CT scanners at EMF Camp this summer. David takes us into that world with history of these tools, a few examples of teeth and bone scans, and then delves into some of the more unusual applications to which his very specialist equipment has been applied. Join me after the break as we cover the lesser known ways to put x-ray technology to work.
If you think of a medical x-ray, it is likely that you are imagining a photographic plate as its imaging device. Clipped to your tooth by your dentist perhaps, or one of the infamous pictures of the hands of [Thomas Edison]’s assistant [Clarence Madison Dally].
As with the rest of photography, the science of x-ray imaging has benefited from digital technology, and it is now well established that your hospital x-ray is likely to be captured by an electronic imaging device. Indeed these have now been in use for so long that their first generation can even be bought by an experimenter for an affordable sum, and that is what the ever-resourceful [Niklas Fauth] with the assistance of [Jan Henrik], has done. Their Trophy DigiPan digital x-ray image sensor was theirs for around a hundred Euros, and though it’s outdated in medical terms it still has huge potential for the x-ray experimenter.
The write-up is a fascinating journey into the mechanics of an x-ray sensor, with the explanation of how earlier devices such as this one are in fact linear CCD sensors which track across the exposed area behind a scintillator layer in a similar fashion to the optical sensor in a flatbed scanner. The interface is revealed as an RS422 serial port, and the device is discovered to be a standalone unit that does not require any commands to start scanning. On power-up it sends a greyscale image, and a bit of Sigrok examination of the non-standard serial stream was able to reveal it as 12-bit data direct from the sensor. From those beginnings they progressed to an FPGA-based data processor and topped it all off with a very tidy power supply in a laser-cut box.
It’s appreciated that x-rays are a particularly hazardous medium to experiment with, and we note from their videos that they are using some form of shielding. The source is a handheld fluoroscope of the type used in sports medicine that produces a narrow beam. If you remember the discovery of an unexpected GameBoy you will be aware that medical electronics seems to be something of a speciality in those quarters, as do autonomous box carriers.
The Japanese X-ray telescope Hitomi has been declared lost after it disintegrated in orbit, torn apart when spinning out of control. The cause is still under investigation but early analysis points to bad data in a software package pushed shortly after an instrument probe was extended from the rear of the satellite. JAXA, the Japanese space agency, lost $286 million, three years of planned observations, and a possible additional 10 years of science research.
Hitomi, also known as ASTRO-H, successfully launched on February 17, 2016 but on March 26th catastrophe struck, leaving only pieces floating in space. JAXA, desperately worked to recover the satellite not knowing the extent of the failure. On April 28th they discontinued their efforts and are now working to determine the reasons for the failure, although a few weeks ago they did provide an analysis of the failure sequence at a press conference.