Medical Hacks

655 Articles

Kind Of The Opposite Of A Lightsaber

November 22, 2018 by 22 Comments

Lightsabers are an elegant weapon for a more civilized age. Did you ever consider that cutting people’s hands off with a laser sword means automatically cauterized wounds and that lack of blood results in a gentler rating from the Motion Picture Association? Movie guidelines aside, a cauterizing pen is found in some first aid kits, but at their core, they are a power source and a heating filament. Given the state of medical technology, this is due for an upgrade, and folks at Arizona State University are hitting all the marks with a combination of near-infrared lasers, gold particles, and protein matrix from silk.

Cauterizing relies on intense heat, or chemicals, to burn flesh but this process uses less power by aiming the near-IR laser at only the selected areas, and since near-IR can penetrate soft-tissue it goes deep without extra heating. The laser heats the gold, and that activates the silk proteins. Early results are positive but lots of testing remains and it still will not belong in the average first aid kit for a while, lasers and all, but surgery for beloved pets and tolerable humans could have recovery time reduced with this advance.

If this doesn’t sate your need for magical space knight weaponry, we have options aplenty.

Via IEEE Spectrum. Image: starwars.com

Brain Cell Electronics Explains Wetware Computing Power

October 28, 2018 by 10 Comments

Neural networks use electronic analogs of the neurons in our brains. But it doesn’t seem likely that just making enough electronic neurons would create a human-brain-like thinking machine. Consider that animal brains are sometimes larger than ours — a sperm whale’s brain weighs 17 pounds — yet we don’t think they are as smart as humans or even dogs who have a much smaller brain. MIT researchers have discovered differences between human brain cells and animal ones that might help clear up some of that mystery. You can see a video about the work they’ve done below.

Neurons have long finger-like structures known as dendrites. These act like comparators, taking input from other neurons and firing if the inputs exceed a threshold. Like any kind of conductor, the longer the dendrite, the weaker the signal. Naively, this seems bad for humans. To understand why, consider a rat. A rat’s cortex has six layers, just like ours. However, whereas the rat’s brain is tiny and 30% cortex, our brains are much larger and 75% cortex. So a dendrite reaching from layer 5 to layer 1 has to be much longer than the analogous neuron in the rat’s brain.

These longer dendrites do lead to more loss in human brains and the MIT study confirmed this by using human brain cells — healthy ones removed to get access to diseased brain cells during surgery. The researchers think that this greater loss, however, is actually a benefit to humans because it helps isolate neurons from other neurons leading to increased computing capability of a single neuron. One of the researchers called this “electrical compartmentalization.” Dig into the conclusions found in the research paper.

We couldn’t help but wonder if this research would offer new insights into neural network computing. We already use numeric weights to simulate dendrite threshold action, so presumably learning algorithms are making weaker links if that helps. However, maybe something to take away from this is that less interaction between neurons and groups of neurons may be more helpful than more interaction.

Watching them probe neurons under the microscope reminded us of probing on an IC die. There’s a close tie between understanding the brain and building better machines so we try to keep an eye on the research going on in that area.

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Bird Beats Cancer With The Help Of A 3D-Printed Prosthetic

October 11, 2018 by 12 Comments

It’s a reasonable certainty that 3D-printing is one day going to be a huge part of medicine. From hip implants to stents that prop open blood vessels to whole organs laid down layer by layer, humans will probably benefit immensely from medical printing. But if they do, the animals will get there first; somebody has to try this stuff out, after all.

An early if an unwilling adopter of 3D-printed medical appliances is [Jary], a 22-year-old Great Pied Hornbill, who recently received a 3D-printed replacement for his casque, the large, mostly hollow protuberance on the front the bird’s skull leading out over the upper beak. There’s no known function for the casque, but it had to be removed since cancer was destroying it and [Jary] wouldn’t have fared well post-surgically without one. Working from CT scans, the veterinary team created a model of the casque as well as a jig to guide the saw during surgery. There’s no word on what filament was used, but we’d guess PLA since it’s biocompatible and available in medical grades. The video below shows some of the surgery; it’s interesting to note that the prosthetic started out natural colored but quickly turned yellow as [Jary] preened with oils from glands near his tail feathers, just like a natural casque would.

Hornbills live to about 40 years old, so [Jary] is just middle-aged. Here’s hoping that he lives a long, happy life in return for being a pioneer in 3D-printing for medical and surgical appliances.

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Towards Open Biomedical Imaging

October 7, 2018 by 9 Comments

We live in a world where anyone can build a CT machine. Yes, anyone. It’s made of laser-cut plywood and it looks like a Stargate. Anyone can build an MRI machine. Of course, these machines aren’t really good enough for medical diagnosis, or good enough to image anything that’s alive for that matter. This project for the Hackaday Prize is something else, though. It’s biomedical imaging put into a package that is just good enough to image your lungs while they’re still in your body.

The idea behind Spectra is to attach two electrodes to the body (a chest cavity, your gut, or a simulator that’s basically a towel wrapped around the inside of a beaker). One of these electrodes emits an AC signal, and the second electrode measures the impedance and phase. Next, move the electrodes and measure again. Do this a few times, and you’ll be able to perform a tomographic reconstruction of the inside of a chest cavity (or beaker simulator).

Hardware-wise, Spectra uses more than two electrodes, thirty-two on the biggest version built so far. All of these electrodes are hooked up to a PCB that’s just under 2″ square, and everything is measured with 16-bit resolution at a 160 kSPS sample rate. To image something, each electrode sends out an AC current. Different tissues have different resistances, and the path taken through the body will have different outputs. After doing this through many electrodes, you can use the usual tomographic techniques to ‘see’ inside the body.

This is a remarkably inexpensive way to image the interior of the human body. No, it doesn’t have the same resolution as an MRI, but then again you don’t need superconducting electromagnets either. We’re really excited to see where this project will go, and we’re looking forward to the inevitable project updates.

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Sounding A Sour Note Can Save People From A Sour Stomach (Or Worse)

September 28, 2018 by 13 Comments

We’ve covered construction of novel music instruments on these pages, and we’ve covered many people tearing down scientific instruments. But today we’ve got something that managed to cross over from one world of “instrument” into another: a music instrument modified to measure a liquid’s density by listening to changes in its pitch.

This exploration started with a mbira, a mechanically simple music instrument. Its row of rigid metal tines was replaced with a single small diameter hollow metal tube. Filling the tube with different liquids would result in different sounds. Those sounds are captured by a cell phone and processed by an algorithm to calculate the difference in relative density of those liquids. Once the procedure was worked out, the concept was verified to work on a super simple instrument built out of everyday parts: a tube mounted on a piece of wood.

At this point we have something that would be a great science class demonstration, but the authors went a step further and described how this cheap sensor can be used to solve an actual problem: detecting counterfeit pharmaceuticals. Changing composition of a drug would also change its density, so a cheap way to compare densities between a questionable sample against a known good reference could be a valuable tool in parts of the world where chemistry labs are scarce.

For future development, this team invites the world to join them applying the same basic idea in other ways, making precise measurements for almost no cost. “Any physical, chemical, or biological phenomena that reproducibly alters the pitch-determining properties of a musical instrument could in principle be measured by the instrument.” We are the ideal demographic to devise new variations on this theme. Let us know what you come up with!

If you need to do quick tests before writing analysis software, audio frequency can be measured using the Google Science Journal app. We’ve seen several hacks turning a cell phone’s camera into instruments like a spectrometer or microscope, but hacks using a phone’s microphone is less common and ripe for exploration. And anyone who manages to make cool measurements while simultaneously making cool music will instantly become a serious contender in our Hackaday Prize music instrument challenge!

[via Science News]

Infection? Your Smartphone Will See You Now

September 24, 2018 by 8 Comments

When Mr. Spock beams down to a planet, he’s carrying a tricorder, a communicator, and a phaser. We just have our cell phones. The University of California Santa Barbara published a paper showing how an inexpensive kit can allow your cell phone to identify pathogens in about an hour. That’s quite a feat compared to the 18-28 hours required by traditional methods. The kit can be produced for under $100, according to the University.

Identifying bacteria type is crucial to prescribing the right antibiotic, although your family doctor probably just guesses because of the amount of time it takes to get an identification through a culture. The system works by taking some — ahem — body fluid and breaking it down using some simple chemicals. Another batch of chemicals known as a LAMP reaction mixture multiplies DNA and will cause fluorescence in the case of a positive result.

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The Use And Abuse Of CT Scanners

September 20, 2018 by 22 Comments

David Mills is as a research scientist at the cutting edge of medical imaging. His work doesn’t involve the scanners you might find yourself being thrust into in a hospital should you be unfortunate enough to injure yourself. He’s working with a higher grade of equipment, he pushes the boundaries of the art with much smaller, very high resolution CT scanners for research at a university dental school.

He’s also a friend of Hackaday and we were excited for his talk on interesting uses for CT scanners at EMF Camp this summer. David takes us into that world with history of these tools, a few examples of teeth and bone scans, and then delves into some of the more unusual applications to which his very specialist equipment has been applied. Join me after the break as we cover the lesser known ways to put x-ray technology to work.

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