The Blood Factory: New Research May Open The Door To Artificial Blood

There were news stories afoot this week with somewhat breathless headlines that suggested a medical breakthrough was at hand: “In a 1st, two people receive transfusions of lab-grown blood cells.” A headline like that certainly catches the eye, especially as the holidays approach and the inevitable calls for increased blood donations that always seem to happen this time of year as the supply gets pinched. Does a headline like that mean that someone is working on completely artificial blood?

As always with this sort of thing, the answer is a mixed bag. Yes, a team in the UK has transfused two patients with a small amount of lab-grown red blood cells, and it’s the first time that particular procedure has been performed. But while the headline is technically correct, the amount transfused was very small, so the day when lab-grown whole blood transfusions replace donated blood isn’t exactly here yet. But the details of what was done and why it was attempted are the really interesting part here, and it’s worth a deep dive because it does potentially point the way to a future where totally synthetic blood may be a real thing.

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Three Norths Align, And It’s Not Even Up North

Sometimes here at Hackaday we bring you stories from slightly outside our world of tech, because they have an interesting angle. Maybe they relate to science or astronomy, or in the case of the UK’s Ordnance Survey explaining how Britain’s three Norths will align, geography.

Some of you may know that the British monarch has two birthdays, but three Norths, what on earth is going on? You’ll guess that two of them are true North, pointing to the North Pole, and magnetic North, pointing to the Earth’s north magnetic field, but how about the third? It’s grid North — the north of the country’s mapping grid system in which the curved surface is projected onto a flat sheet.

It aligns with true North at 2 degrees West of Greenwich, and the news is that for the first time ever due to movement of the magnetic North Pole, the three different Norths will align at a point in the south of England. Magnetic North has been on the move at some pace over the last few decades, from a position somewhere in the Canadian Arctic islands northwards, and it so happens that for Brits its direction is briefly aligned with our view of the Pole. The Ordnance Survey story is of some interest, but for a wealth of information it’s worth consulting NASA. Take a look at the video below the break.

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Dosimetry: Measuring Radiation

Thanks to stints as an X-ray technician in my early 20s followed by work in various biology labs into my early 40s, I’ve been classified as an “occupationally exposed worker” with regard to ionizing radiation for a lot of my life. And while the jobs I’ve done under that umbrella have been vastly different, they’ve all had some common ground. One is the required annual radiation safety training classes. Since the physics never changed and the regulations rarely did, these sessions would inevitably bore everyone to tears, which was a pity because it always felt like something I should be paying very close attention to, like the safety briefings flight attendants give but everyone ignores.

The other thing in common was the need to keep track of how much radiation my colleagues and I were exposed to. Aside from the obvious health and safety implications for us personally, there were legal and regulatory considerations for the various institutions involved, which explained the ritual of finding your name on a printout and signing off on the dose measured by your dosimeter for the month.

Dosimetry has come a long way since I was actively considered occupationally exposed, and even further from the times when very little was known about the effects of radiation on living tissue. What the early pioneers of radiochemistry learned about the dangers of exposure was hard-won indeed, but gave us the insights needed to develop dosimetric methods and tools that make working with radiation far safer than it ever was.

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Conducting Plastic Can Replace Metal

The University of Chicago has announced they have created a material that behaves like plastic but conducts like metal. They also say they don’t fully understand why it works yet. Usually, good conductors like metals have very orderly atomic structures, something that plastics tend not to have.

The material is based on nickel, carbon, and sulfur. The resulting material was conductive and stable. However, the atomic structure isn’t orderly like a traditional conductor.

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Nanoassembly With Water

Water is sometimes known as the universal solvent. But researchers at Harvard want to use water to put things together instead of taking them apart. Really small things. In the video below, you can see a simple 3D-printed machine that braids microscopic fibers.

The key appears to be surface tension and capillary action. A capillary machine uses channels that repel floating objects. By moving the channel, materials move to avoid the channel, and by shaping the channel, various manipulations can occur, including braiding. This is one of those things that is easier to understand when you see it, so if it doesn’t make sense, watch the video below. The example uses tiny Kevlar fibers.

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Europe’s Energy Squeeze Pushes Large Hadron Collider To Halt Operations

Energy prices have been in the news more often than not lately, as has war. The two typically go together, as conflicts tend to impact on the supply and trade of fossil fuels.

With Europe short on gas and its citizens contemplating a cold winter, science is feeling the pinch, too. CERN has elected to shut down the Large Hadron Collider early to save electricity.

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PySpectrometer version 2, showing mini spectroscope, 4 inch display and hand for scale

Pi-based Spectrometer Gets An Upgrade

Here at Hackaday, we love to see projects re-visited and updated after we’ve covered them on the site. It’s always exciting to see what the creators come up with next, and this Pi-Based Spectrometer project is a great example of that.

[LesWright] found himself with a problem when the new version of Raspberry Pi operating system was released (Bullseye), and it broke some functionality on his original software. Rather than just fix the issues, [Les] chose to rewrite the software more dramatically and has ended up with a much more capable spectrometer that is able to match professional devices costing many times more.

Screenshot of Waterfall Display for PySpectrometer 2
Screenshot of Waterfall Display for PySpectrometer 2

By using multi-wavelength calibration and polynomial regression data, the new version is much more accurate and can now resolve wavelengths down to +/- 1nm.

The whole project is now written in OpenCV, and there’s a nifty new waterfall spectrum display, that will show changes in measured spectra over time.

A low-cost benchtop spectroscope is coupled to a RaspberryPi Camera via a CCTV zoom lens and the whole setup is mounted to a small block of aluminium for thermal and mechanical stability. The spectroscope is pointed at a fluorescent lamp and the user is guided through a calibration routine to tune the software to the hardware.

We’re impressed with the precision [Les] has achieved with his builds, and the write-up is sufficiently detailed to allow others to follow in his footsteps. We’d love to see if readers build one themselves, and what they use them for!

If you want to read up on the original build, you can find our article here. We’ve covered several spectrometry projects in the past, including this Gamma-Ray Spectrometer and this one based around an STM32 Nucleo board. Continue reading “Pi-based Spectrometer Gets An Upgrade”