Science

1290 Articles

Mirror, Mirror, Electron Mirror…

February 23, 2024 by 2 Comments

If you look into an electron mirror, you don’t expect to see your reflection. As [Anthony Francis-Jones] points out, what you do see is hard to explain. The key to an electron mirror is that the electric and magnetic fields are 90 degrees apart, and the electrons are 90 degrees from both.

You need a few strange items to make it all work, including an electron gun with a scintillating screen in a low-pressure tube. Once he sets an electric field going, the blue line representing the electrons goes from straight to curved.

Continue reading “Mirror, Mirror, Electron Mirror…” →

Rebuilding A $700k Refrigerator

February 21, 2024 by 20 Comments

When cleaning out basements, garages, or storage units we often come across things long forgotten. Old clothes, toys, maybe a piece of exercise equipment, or even an old piece of furniture. [Ben] and [Hugh] were in a similar situation cleaning out an unused lab at the University of California Santa Barbara and happened upon an old refrigerator. This wasn’t just a mini fridge left over from a college dorm, though. This is a dilution refrigerator which is capable of cooling things down to near absolute zero, and these scientists are trying to get it to its former working state.

The pair are hoping to restore the equipment to perform dark matter experiments, but the refrigerator hasn’t been in use since about 2016 (and doesn’t have an instruction manual), which is a long time for a piece of specialty scientific equipment to be collecting dust. The first step is to remove wiring and clean it of all the grime it’s accumulated in the last decade. After that, the pair work to reassemble the layers of insulation around the main cooling plate and then hook up a vacuum pump to the device which also needed some repair work.

The critical step at this point is to evacuate the refrigerant lines so they can be filled with expensive Helium-3 and Helium-4. The problem is that there’s still some of this valuable gas in the lines that needs to be recovered, but the risk is that if any air gets into the cold section of the refrigerator it will freeze and clog the whole system. After chasing some other electrical and vacuum gremlins and discovering a manual from a similar refrigerator, they eventually get it up and running and ready for new scientific experiments. While most of us won’t discover a fridge like this cleaning out our attics, this refrigerator powered by rubber bands is a little more accessible to the rest of us.

Continue reading “Rebuilding A $700k Refrigerator” →

New Modelling Shows That Flat Protoplanets Might Be A Thing

February 20, 2024 by 23 Comments
Surface density of the benchmark run disc (in g cm−2). The disc becomes gravitationally unstable and fragments. Four of the fragments or protoplanets are followed until they reach density 10−3 g cm−3. (Credit: Fenton et al., 2024)
Surface density of the benchmark run disc (in g cm−2). The disc becomes gravitationally unstable and fragments. Four of the fragments or protoplanets are followed until they reach density 10−3 g cm−3. (Credit: Fenton et al., 2024)

While the very idea of a flat planet millions of years after its formation is patently ridiculous, recent modelling shows that during the protostar phase – where material from a nebula is drawn around a hydrostatic core into an accretion disc – it is likely that many of of the protoplanets which form inside a fragmentary protostar accretion disc take on a strongly oblate spheroid shape, rather than a spherical one. This according to [Adam Fenton] and [Dimitris Stamatellos], who ran half a million CPU hours worth of simulation time at the UK’s DiRAC HPC facility, per the University of Central Lancashire (UCLan) press release.

The research was published in the February 2024 issue of Astronomy & Astrophysics, titled The 3D structure of disc-instability protoplanets.

Where this research is essential is not just in our understanding of how our own solar system came to be – including our own oblate spheroid Earth – but also in interpreting what we observe via the Hubble Space Telescope, James Webb Space Telescope and others as we examine areas of the observable Universe such as the Orion Nebula, which is one of the regions with the most actively forming stars. By comparing these simulations with observations, we may find that the simulation matches perfectly, matches partially, or perhaps not at all, which provides data to refine the simulation, but also helps to reconsider how observations were previously interpreted.

Measuring Trees Via Satellite Actually Takes A Great Deal Of Field Work

February 20, 2024 by 11 Comments

Figuring out what the Earth’s climate is going to do at any given point is a difficult task. To know how it will react to given events, you need to know what you’re working with. This requires an accurate model of everything from ocean currents to atmospheric heat absorption and the chemical and literal behavior of everything from cattle to humans to trees.

In the latter regard, scientists need to know how many trees we have to properly model the climate. This is key, as trees play a major role in the carbon cycle by turning carbon dioxide into oxygen plus wood. But how do you count trees at a continental scale? You’ll probably want to get yourself a nice satellite to do the job.

Continue reading “Measuring Trees Via Satellite Actually Takes A Great Deal Of Field Work” →

Gold Recovery From E-Waste With Food-Waste Amyloid Aerogels

February 20, 2024 by 11 Comments

A big part of the recycling of electronic equipment is the recovery of metals such as gold. Usually the printed circuit boards and other components are shredded, sorted, and then separated. But efficiently filtering out specific metals remains tricky and adds to the cost of recycling. A possible way to optimize the recovery of precious metals like gold could be through the use of aerogels composed out of protein amyloids to which one type of metal would preferentially adsorb. According to a recent research article in Advanced Materials by [Mohammad Peydayesh] and colleagues, such aerogels could be created from protein waste from the food industry.

The adsorption mechanism of the protein amyloids is a feature of these proteins which form chelants, which are structures that can effectively bond to metal ions. These are usually organic compounds, and are used in certain medical treatments where heavy metal poisoning is involved (chelation therapy). By having these protein amyloids in an aerogel structure, the surface area for adsorption is maximized, which in the research article is said to have an efficiency of 93.3% for gold recovery, while leaving the other metals in the aqua regia solution (nitric and hydrochloric acid) mostly untouched.

Of note here is that although the food waste protein angle is taken, the experiment used whey protein. This is also one of the most popular food supplements in the world, to the point that microbial production of whey is a thing now. Although this doesn’t invalidate the aerogel chelation approach to e-waste recycling, it’s a curious omission in the article that does not appear to be addressed.

ForceGen: Using A Diffusion Model To Help Design Novel Proteins

February 19, 2024 by 1 Comment

Although proteins are composed out of only a small number of distinct amino acids, this deceptive simplicity quickly vanishes when considering the many possible sequences across a protein, not to mention the many ways in which a single 1D protein sequence can fold into a 3D protein shape with a specific functionality. Although natural evolution has done much of the legwork here already, figuring out new sequences and their functionality is a daunting task where increasingly deep learning algorithms are being applied. As [Bo Ni] and colleagues report in a research article in Science Advances, the hardest challenge is designing a protein sequence based on the desired functionality. They then demonstrate a way to use a generative model to speed up this process.

They set out to design proteins with specific mechanical properties, for which they used the known unfolding characteristics of various protein sequences to train a diffusion model. This approach is thus more akin to the technology behind image generation algorithms like DALL-E than LLMs. Using the trained diffusion model it was then possible to generate likely sequences of which the properties could then be simulated, with favorable results.

As a large data set aid, such a diffusion model could conceivably be very useful in fields even beyond protein synthesis, automating tedious tasks and conceivably speeding up discoveries.

Low-Cost Saliva-based Biosensor For Cancer Detection

February 18, 2024 by 12 Comments

More and more biomarkers that can help in the early diagnosis of diseases like cancer are being discovered every year, but often the effective application relies on having diagnostic methods that are both affordable and as least invasive as possible. This is definitely true in the case of breast cancers, where the standard diagnostic method after seeing something ‘odd’ on a scan is to perform a biopsy so that a tissue sample can be tested in a laboratory. What [Hsiao-Hsuan Wan] and colleagues demonstrate in a recently published research article in the Journal of Vacuum Science & Technology B is a way to use saliva on disposable test strips to detect the presence of cancer-related biomarkers. Best of all, the system could be very affordable.

The two biomarkers tested in this experiment are HER2 (in 10 – 30% of breast cancer cases) and CA 15-3, both of which are indicative of a variety of cancers, including breast cancers. According to the researchers, the levels of these biomarkers in saliva can be correlated to those in blood serum. Where other biosensors may include the read-out circuitry – making those disposable and expensive – here the disposable part is the test strips which are plated with electrodes.

Continue reading “Low-Cost Saliva-based Biosensor For Cancer Detection” →