A picture of a single water droplet on top of what appears to be a page from a chemistry text. An orange particle is attached to the right side of the droplet and blue and black tendrils diffuse through the drop from it. Under the water drop, the caption tells us the reaction we're seeing is "K2Cr2O7+ 3H2O2 + 4H2SO4 = K2SO4+Cr2(SO4)3+7H2O+3O2(gas)"

Water Drops Serve As Canvas For Microchemistry Art

May 5, 2025 by Navarre Bartz 3 Comments

If you’re like us and you’ve been wondering where those viral videos of single water drop chemical reactions are coming from, we may have an answer. [yu3375349136], a scientist from Guangdong, has been producing some high quality microchemistry videos that are worth a watch.

While some polyglots out there won’t be phased, we appreciate the captioning for Western audiences using the elemental symbols we all know and love in addition to the Simplified Chinese. Reactions featured are typically colorful, but simple with a limited number of reagents. Being able to watch diffusion of the chemicals through the water drop and the results in the center when more than one chemical is used are mesmerizing.

We do wish there was a bit more substance to the presentation, and we’re aware not all readers will be thrilled to point their devices to Douyin (known outside of China as TikTok) to view them, but we have to admit some of the reactions are beautiful.

If you’re interested in other science-meets-art projects, how about thermal camera landscapes of Iceland, and given the comments on some of these videos, how do you tell if it’s AI or real anyway?

A human hand in a latex glove holds a test tube filled with red liquid labeled H5N1. In the background is an out of focus image of a chicken.

Preparing For The Next Pandemic

May 2, 2025 by Navarre Bartz 69 Comments

While the COVID-19 pandemic wasn’t an experience anyone wants to repeat, infections disease experts like [Dr. Pardis Sabeti] are looking at what we can do to prepare for the next one.

While the next pandemic could potentially be anything, there are a few high profile candidates, and bird flu (H5N1) is at the top of the list. With birds all over the world carrying the infection and the prevalence in poultry and now dairy agriculture operations, the possibility for cross-species infection is higher than for most other diseases out there, particularly anything with an up to 60% fatality rate. Only one of the 70 people in the US who have contracted H5N1 recently have died, and exposures have been mostly in dairy and poultry workers. Scientists have yet to determine why cases in the US have been less severe.

To prevent an H5N1 pandemic before it reaches the level of COVID and ensure its reach is limited like earlier bird and swine flu variants, contact tracing of humans and cattle as well as offering existing H5N1 vaccines to vulnerable populations like those poultry and dairy workers would be a good first line of defense. So far, it doesn’t seem transmissible human-to-human, but more and more cases increase the likelihood it could gain this mutation. Keeping current cases from increasing, improving our science outreach, and continuing to fund scientists working on this disease are our best bets to keep it from taking off like a meme stock.

Whatever the next pandemic turns out to be, smartwatches could help flatten the curve and surely hackers will rise to the occasion to fill in the gaps where traditional infrastructure fails again.

Continue reading “Preparing For The Next Pandemic” →

An illustration of two translucent blue hands knitting a DNA double helix of yellow, green, and red base pairs from three colors of yarn. Text in white to the left of the hands reads: "Evo 2 doesn't just copy existing DNA -- it creates truly new sequences not found in nature that scientists can test for useful properties."

LLMs Coming For A DNA Sequence Near You

April 24, 2025 by Navarre Bartz 16 Comments

While tools like CRISPR have blown the field of genome hacking wide open, being able to predict what will happen when you tinker with the code underlying the living things on our planet is still tricky. Researchers at Stanford hope their new Evo 2 DNA generative AI tool can help.

Trained on a dataset of over 100,000 organisms from bacteria to humans, the system can quickly determine what mutations contribute to certain diseases and what mutations are mostly harmless. An “area we are hopeful about is using Evo 2 for designing new genetic sequences with specific functions of interest.”

To that end, the system can also generate gene sequences from a starting prompt like any other LLM as well as cross-reference the results to see if the sequence already occurs in nature to aid in predicting what the sequence might do in real life. These synthetic sequences can then be made using CRISPR or similar techniques in the lab for testing. While the prospect of building our own Moya is exciting, we do wonder what possible negative consequences could come from this technology, despite the hand-wavy mention of not training the model on viruses to “to prevent Evo 2 from being used to create new or more dangerous diseases.”

We’ve got you covered if you need to get your own biohacking space setup for DNA gels or if you want to find out more about powering living computers using electricity. If you’re more curious about other interesting uses for machine learning, how about a dolphin translator or discovering better battery materials?

DolphinGemma Seeks To Speak To Dolphins

April 24, 2025 by Navarre Bartz 42 Comments

Most people have wished for the ability to talk to other animals at some point, until they realized their cat would mostly insult them and ask for better service, but researchers are getting closer to a dolphin translator.

DolphinGemma is an upcoming LLM based on the recordings from the Wild Dolphin Project. Using the hours and hours of dolphin sounds recorded by researchers over the decades, the hope is that the LLM will allow us to communicate more effectively with the second most intelligent species on the planet.

The LLM is designed to run in the field on Google Pixel phones, due to it being based on Google’s in-house Gemini product, which is a bit less cumbersome than hauling a mainframe on a dive. The Wild Dolphin Project currently uses the Georgia Tech developed CHAT (Cetacean Hearing Augmentation Telemetry) device which has a Pixel 6 at its heart, but the newer system will be bumped up to a Pixel 9 to take advantage of all those shiny new AI processing advances. Hopefully, we’ll have a better chance of catching when they say, “So long and thanks for all the fish.”

If you’re curious about other mysterious languages being deciphered by LLMs, we have you covered.

Continue reading “DolphinGemma Seeks To Speak To Dolphins” →

Playstacean Evolves The PSOne Into The Crab It Was Always Meant To Be

April 3, 2025 by Navarre Bartz 6 Comments

Odd hardware designs crop up in art and renders far more frequently than in the flesh, but console modder [GingerOfOz] felt the need to bring [Anh Dang]’s image of the inevitable carcinization of our gaming consoles to life.

Starting with the image as inspiration, [GingerOfOz] got to work in CAD, creating an entirely new shell for the battered PSOne he adopted for the project. The final product is slightly less curvy than the picture, but some artistic license was necessary to go from the page to the real world.

The enclosure itself looks straightforward, if a bit tedious, but the articulating crab controller is a work of art itself. He could’ve made the arms static or non-functional, but they’re a fully-functional PlayStation controller that can move around just like on your favorite crustacean at the beach, minus the pinching. We love this whimsical take on the console mod which is a breath of salty air to the continuous race to get increasingly complex consoles into handheld form, although there’s certainly nothing wrong with that!

If you’re looking for some other console mods, how about this Apple M1 inside a Wii or getting your old Ouya up-and-running again?

Continue reading “Playstacean Evolves The PSOne Into The Crab It Was Always Meant To Be” →

Have Li-ion Batteries Gone Too Far?

March 13, 2025 by Navarre Bartz 84 Comments

The proliferation of affordable lithium batteries has made modern life convenient in a way we could only imagine in the 80s when everything was powered by squadrons of AAs, or has it? [Ian Bogost] ponders whether sticking a lithium in every new device is really the best idea.

There’s no doubt, that for some applications, lithium-based chemistries are a critically-enabling technology. NiMH-based EVs of the 1990s suffered short range and slow recharge times which made them only useful as commuter cars, but is a flashlight really better with lithium than with a replaceable cell? When household electronics are treated as disposable, and Right to Repair is only a glimmer in the eye of some legislators, a worn-out cell in a rarely-used device might destine it to the trash bin, especially for the less technically inclined.

[Bogost] decries “the misconception that rechargeables are always better,” although we wonder why his article completely fails to mention the existence of rechargeable NiMH AAs and AAAs which are loads better than their forebears in the 90s. Perhaps even more relevantly, standardized pouch and cylindrical lithium cells are available like the venerable 18650 which we know many makers prefer due to their easy-to-obtain nature. Regardless, we can certainly agree with the author that easy to source and replace batteries are few and far between in many consumer electronics these days. Perhaps new EU regulations will help?

Once you’ve selected a battery for your project, don’t forget to manage it if it’s a Li-ion cell. With great power density, comes great responsibility.

Smartwatches Could Flatten The Curve Of The Next Pandemic

March 4, 2025 by Navarre Bartz 71 Comments

While we’d like to think that pandemics and lockdowns are behind us, the reality is that a warming climate and the fast-paced travel of modern life are a perfect storm for nasty viruses. One thing that could help us curb the spread of the next pandemic may already be on your wrist.

Researchers at Aalto University, Stanford University, and Texas A&M have found that the illness detection features common to modern smartwatches are advanced enough to help people make the call to stay home or mask up and avoid getting others sick. They note we’re already at 88% accuracy for early detection of COVID-19 and 90% for the flu. Combining data from a number of other studies on smartwatch accuracy, epidemiology, behavior, and biology, the researchers were able to model the possible outcomes of this early detection on the spread of future diseases.

“Even just a 66-75 percent reduction in social contacts soon after detection by smartwatches — keeping in mind that that’s on a par with what you’d normally do if you had cold symptoms — can lead to a 40-65 percent decrease in disease transmission compared to someone isolating from the onset of symptoms,” says Märt Vesinurm.

We’ve got you covered if you’re looking for a smartwatch that looks a bit like a hospital wristband and we’ve also covered one that’s alive. That way, you’ll have a slimy friend when you’re avoiding other humans this time around. And when it’s time to develop a vaccine for whatever new bug is after us, how do MRNA vaccines work anyway?