Kathleen Lonsdale Saw Through The Structure Of Benzene

The unspoken promise of new technologies is that they will advance and enhance our picture of the world — that goes double for the ones that are specifically designed to let us look closer at the physical world than we’ve ever been able to before. One such advancement was the invention of X-ray crystallography that let scientists peer into the spatial arrangements of atoms within a molecule. Kathleen Lonsdale got in on the ground floor of X-ray crystallography soon after its discovery in the early 20th century, and used it to prove conclusively that the benzene molecule is a flat hexagon of six carbon atoms, ending a decades-long scientific dispute once and for all.

Benzene is an organic chemical compound in the form of a colorless, flammable liquid. It has many uses as an additive in gasoline, and it is used to make plastics and synthetic rubber. It’s also a good solvent. Although the formula for benzene had been known for a long time, the dimensions and atomic structure remained a mystery for more than sixty years.

Kathleen Lonsdale was a crystallography pioneer and developed several techniques to study crystal structures using X-rays. She was brilliant, but she was also humble, hard-working, and adaptable, particularly as she managed three young children and a budding chemistry career. At the outbreak of World War II, she spent a month in jail for reasons related to her staunch pacifism, and later worked toward prison reform, visiting women’s prisons habitually.

After the war, Kathleen traveled the world to support movements that promote peace and was often asked to speak on science, religion, and the role of women in science. She received many honors in her lifetime, and became a Dame of the British Empire in 1956. Before all of that, she honored organic chemistry with her contributions.

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We All Need A Win Sometimes, So Make Them Yourself

We all need the occasional win when it comes to work or personal projects. Being able to feel that payoff of progress and satisfaction is deeply important, because if everything is always uphill, that’s a recipe for burnout. Avoiding that is important enough to explore how to set oneself up for a few easy wins.

Getting the occasional win helps us stay motivated, creative, and fulfilled. Meaningful work can deliver on this, but many of us rely on hobbies to make up any shortfall. Sometimes, that isn’t enough. Hobbies themselves can end up feeling like a chore, and when that happens, they cease to provide respite. The good news is that I believe it is possible to exploit the benefits of hobbies to deliver supplemental “wins” when they are needed most, and I’ll explain how.

I have found that successes do not have to be hard-won in order to be beneficial, but they do need to be relevant to one’s passions and interests. So, when naturally-occurring successes come too few and far between, and hobbies aren’t doing the trick, use knowledge of yourself to stack the deck for some easy wins. It can tip the scales towards feeling meaningful progress and fulfillment in the face of what could otherwise lead to burnout. Continue reading “We All Need A Win Sometimes, So Make Them Yourself”

You Can’t Put The Toothpaste Back In The Tube, But It Used To Be Easier

After five years of research, Colgate-Palmolive recently revealed Australia’s first recyclable toothpaste tube. Why is this exciting? They are eager to share the design with the rest of the toothpaste manufacturers and other tube-related industries in an effort to reduce the volume of plastic that ends up in landfills. It may not be as life-saving as seat belts or the Polio vaccine, but the move does bring Volvo and OG mega open-sourcer Jonas Salk to mind.

Today, toothpaste tubes are mostly plastic, but they contain a layer of aluminum that helps it stay flattened and/or rolled up. So far, multi-layer packaging like this isn’t accepted for recycling at most places, at least as far as Australia and the US are concerned. In the US, Tom’s of Maine was making their tubes entirely out of aluminum for better access to recycling, but they have since stopped due to customer backlash.

Although Colgate’s new tubes are still multi-layered, they are 100% HDPE, which makes them recyclable. The new tubes are made up of different thicknesses and grades of HDPE so they can be easily squeezed and rolled up.

Toothpaste Before Tubes

Has toothpaste always come in tubes? No it has not. It also didn’t start life as a paste. Toothpaste has been around since 5000 BC when the Egyptians made tooth powders from the ashes of ox hooves and mixed them with myrrh and a few abrasives like powdered eggshells and pumice. We’re not sure what they kept it in — maybe handmade pottery with a lid, or a satchel made from an animal’s pelt or stomach.

The ancient Chinese used ginseng, salt, and added herbal mints for flavoring. The Greeks and Romans tried crushed bones, oyster shells, tree bark, and charcoal, which happens to be back in vogue. There is evidence from the late 1700s showing that people once brushed with burnt breadcrumbs.

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PipeWire, The Newest Audio Kid On The Linux Block

Raise your hand if you remember when PulseAudio was famous for breaking audio on Linux for everyone. For quite a few years, the standard answer for any audio problem on Linux was to uninstall PulseAudio, and just use ALSA. It’s probably the case that a number of distros switched to Pulse before it was quite ready. My experience was that after a couple years of fixing bugs, the experience got to be quite stable and useful. PulseAudio brought some really nice features to Linux, like moving sound streams between devices and dynamically resampling streams as needed.

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Human Google: Ruth Freitag, Isaac Asimov, And Bibliographies

You don’t often turn on a light and think, “That power company is sure on the ball!” You generally only think of them when the lights go out without warning. I think the same is true of search. You don’t use Google or DuckDuckGo or any of the other search engines and think “Wow! How awesome it is to have this much information at your fingertips.” Well. Maybe a little, but it is hard to remember just how hard it was to get at information in the pre-search-engine age.

I were thinking about this the other day when I read that Ruth Freitag had died last year. Ruth had the unglamorous but very important title of reference librarian. But she wasn’t just an ordinary librarian. She worked for the Library of Congress and was famous in certain circles, counting among her admirers Isaac Asimov and Carl Sagan.

Ruth Freitag in 1985

You might wonder why a reference librarian would have fans. Turns out, high-powered librarians do more than just find books on the shelves for you. They produced bibliographies. If you wanted to know about, say, Halley’s comet today, you’d just do a Google search. Even if you wanted to find physical books, there are plenty of places to search: Google Books, online bookstores, and so on. But in the 1970s your options were much more limited.

Turns out, Ruth had an interest and expertise in astronomy, but she also had a keen knowledge of science and technology in general. By assembling comprehensive annotated bibliographies she could point people like Asimov and Sagan to the books they needed just like we would use Google, today.

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How To Get Into Cars: Land Speed Racing

Land speed racing is one of the oldest forms of motorsport, and quite literally consists of going very, very fast in (ideally) a straight line. The higher the speed your car can attain, the better! It’s about the pure pursuit of top speed above all else, and building a car to compete is a calling for a dedicated few. If you’d like to join them, here’s how to go about it.

Faster, Faster, Faster!

A great example of the “36HP” Volkswagen class, which challenges competitors to set land speed records using only classic VW engines, with categories for various levels of modification. Note the aero wheels and raked stance. Credit: Utah Salt Flats Racing Association

While taking the outright land speed record typically requires a jet-engined sled of singular design, there is plenty of land speed competition to be had in various classes for competitors fielding their own entries. There are vintage classes for older technology engines, still popular from the dawn of hotrodding, like Ford Flathead V8s and other contemporary motors. There are also classes split by engine displacement, number of cylinders, aerodynamic modifications, or the type of fuel used.

Racers often pick a record or set of records they wish to beat – for example, wanting to set the the fastest speed for a gasoline-powered, naturally-aspirated four cylinder – and build their car to that end. Alternatively, a racer might build a car with a large V8 engine, for example, to compete in one class, and then disable several cylinders on a later run to try and snatch records in lower classes as well. Continue reading “How To Get Into Cars: Land Speed Racing”

Alice Ball Steamrolled Leprosy

Leprosy is a bacterial disease that affects the skin, nerves, eyes, and mucosal surfaces of the upper respiratory tract. It is transmitted via droplets and causes skin lesions and loss of sensation in these regions. Also known as Hansen’s disease after the 19th century scientist who discovered its bacterial origin, leprosy has been around since ancient times, and those afflicted have been stigmatized and outcast for just as long. For years, people were sent to live the rest of their days in leper colonies to avoid infecting others.

The common result of injecting chaulmoogra oil. Image via Stanford University

Until Alice Ball came along, the only thing that could be done for leprosy — injecting oil from the seeds of an Eastern evergreen tree — didn’t really do all that much to help. Eastern medicine has been using oil from the chaulmoogra tree since the 1300s to treat various maladies, including leprosy.

The problem is that although it somewhat effective, chaulmoogra oil is difficult to get it into the body. Ingesting it makes most people vomit. The stuff is too sticky to be applied topically to the skin, and injecting it causes the oil to clump in abscesses that make the patients’ skin look like bubble wrap.

In 1866, the Hawaiian government passed a law to quarantine people living with leprosy on the tiny island of Moloka’i. Every so often, a ferry left for the island and delivered these people to their eventual death. Most patients don’t die of leprosy, but from secondary infection or disease. By 1915, there were 1,100 people living on Moloka’i from all over the United States, and they were running out of room. Something had to be done.

Professor Alice Ball hacked the chemistry of chaulmoogra oil and made it less viscous so it could be easily injected. As a result, it was much more effective and remained the ideal treatment until the 1940s when sulfate antibiotics were discovered. So why haven’t you heard of Alice before? She died before she could publish her work, and then it was stolen by the president of her university. Now, over a century later, Alice is starting to get the recognition she deserves.

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