Medical Hacks

670 Articles

So What Is Protein Folding, Anyway?

April 14, 2020 by 26 Comments

The current COVID-19 pandemic is rife with problems that hackers have attacked with gusto. From 3D printed face shields and homebrew face masks to replacements for full-fledged mechanical ventilators, the outpouring of ideas has been inspirational and heartwarming. At the same time there have been many efforts in a different area: research aimed at fighting the virus itself.

Getting to the root of the problem seems to have the most potential for ending this pandemic and getting ahead of future ones, and that’s the “know your enemy” problem that the distributed computing effort known as Folding@Home aims to address. Millions of people have signed up to donate cycles from spare PCs and GPUs, and in the process have created the largest supercomputer in history.

But what exactly are all these exaFLOPS being used for? Why is protein folding something to direct so much computational might toward? What’s the biochemistry behind this, and why do proteins need to fold in the first place? Here’s a brief look at protein folding: what it is, how it happens, and why it’s important.

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Disinfect PPE On The Cheap With This Hardware Store UV-C Cabinet

April 12, 2020 by 91 Comments

The current situation has given closet germaphobes the world over a chance to get out there and clean the hell out of everything. Some of it may be overdone; we ourselves can cop to a certain excess as we wipe down cans and boxes when returning from a run to the grocery store. But sometimes disinfection is clearly indicated, and having an easy way to kill the bugs on things like face masks can make a big difference by extending the life of something that would normally be disposable. That’s where this quick and easy UV-C germicidal cabinet really shines.

The idea behind [Deeplocal]’s “YouVee” is to be something that can be quickly cobbled together from parts that can be picked up at any big-box home store, thereby limiting the number of trips out. You might even have everything needed already, which would make this a super simple build. The business end is a UV-C germicidal fluorescent lamp, of the kind used in clarifiers for backyard ponds. A fluorescent droplight is modified to accept the lamp by snipping off a bit of plastic, and the lamp is attached to the inside of the lid of a sturdy black plastic tote. The interior of the tote is lined with aluminum tape and a stand for items to be disinfected is made from a paint roller screen. The clever bit is the safety interlock; to prevent exposure to UV, the lamp needs to be unplugged before removing the lid. Check out the full build tutorial for details.

We can’t vouch for YouVee’s germicidal efficacy, but it seems like a solid design. If you have doubts, you could always measure the UV-C flux easily, or you could build a smaller version of this peroxide vapor PPE sterilizer, just to be sure.

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What Does A Dependable Open Source Ventilator Look Like?

April 9, 2020 by 61 Comments

Ventilators are key in the treating the most dire cases of coronavirus. The exponential growth of infections, and the number of patients in respiratory distress, has outpaced the number of available ventilators. In times of crisis, everyone looks for ways they can help, and one of the ways the hardware community has responded is in work toward a ventilator design that can be rapidly manufactured to meet the need.

The difficult truth is that the complexity of ventilator features needed to treat the sickest patients makes a bootstrapped design incredibly difficult, and I believe impossible to achieve in quantity on this timeline. Still, a well-engineered and clinically approved open source ventilator might deliver many benefits beyond the current crisis. Let’s take a look at some of the efforts we’ve been seeing recently and what it would take to pull together a complete design.

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Real Engineering Behind Ventilators

April 7, 2020 by 40 Comments

Experts on cognition tell us that most people think they know more than they really do. One particular indicator for that is if someone is an expert in one field and they feel like all other fields relate to theirs (everything boils down to math or chemistry or physics, for example). This causes them to be overconfident on things they don’t actually know about. When it became clear that the current virus crisis might lead to a shortage of ventilators, many electronic experts set about to design low-cost easy to replicate ventilators. How hard is it, after all, to squeeze a bag once every few seconds? But it turns out, there are a lot of details you need to know to do it right. [Real Engineering] and [Real Science] joined to create an excellent video that covers a lot of what you need to know. You can see the video below. The video shows a few designs that — while motivated by altruism — would probably do more harm than good if used on real patients.

The video’s creator is a biomedical engineer who worked in the past for Medtronic — a maker of ventilators who, by the way, recently open-sourced one of their designs. They also had [Dr. Rohin Francis], who has a medical YouTube channel, fact check the video. and provide some on-screen background We learned a few new medical terms and found that a high-end ventilator made in one factory gets built at about 225 per week. They think they can increase to 500.

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Reliability Check: Consumer And Research-Grade Wrist-Worn Heart Rate Monitors

April 7, 2020 by 12 Comments

Wearables are ubiquitous in today’s society. Such devices have evolved in their capabilities from step counters to devices that measure calories burnt, sleep, and heart rate. It’s pretty common to meet people using a wearable or two to track their fitness goals. However, a big question remains unanswered. How accurate are these wearable devices? Researchers from the Big Ideas Lab evaluated a group of wearables to assess their accuracy in measuring heart rate.

Unlike other studies with similar intentions, the Big Ideas Lab specifically wanted to address whether skin color had an effect on the accuracy of the heart rate measurements, and an FDA-cleared Bittium Faros 180 electrocardiogram was used as the benchmark. Overall, the researchers found that there was no difference in accuracy across skin tones, meaning that the same wearable will measure heart rate on a darker skin-toned individual the same as it would on a lighter skin-toned. Phew!

However, that may be the only good news for those wanting to use their wearable to accurately monitor their heart rate. The researchers found the overall accuracy of the devices relative to ECG was a bit variable with average errors of 7.2 beats per minute (BPM) in the consumer-grade wearables and 13.9 BPM in the research-grade wearables at rest. During activity, errors in the consumer-grade wearables climbed to an average of 10.2 BPM and 15.9 in the research-grade wearables. It’s interesting to see that the research-grade devices actually performed worse than the consumer devices.

And there’s a silver lining if you’re an Apple user. The Apple Watch performed consistently better than all other devices with mean errors between 4-5 BPM during rest and during activity, unless you’re breathing deeply, which threw the Apple for a loop.

So, it seems as if wrist-worn heart rate monitors still have some work to do where accuracy is concerned. Although skin tone isn’t a worry, they all become less accurate when the subject is moving around.

If you’d like to try your own hand with fitness trackers, have a look at this completely open project, or go for the gold standard with a wearable DIY ECG.

A Touchless Handwashing Timer Comes In Handy

April 3, 2020 by 23 Comments

In 2020, it’s no longer enough to simply wash your hands. You’ve got to do it right. Proper process involves rubbing soap and water over every surface of your hands, and taking a full 20 seconds to do the job. While many recommend singing various popular songs to keep time, that can be more than a little embarassing in shared spaces. [Alex Glow] instead created this simple timer to help out.

The timer is built on the Adafruit Circuit Playground Express, a devboard that features 10 RGB LEDs already onboard, making the project a cinch. It also comes with a MEMS microphone and a light sensor all ready to go. Thus, with a bit of code, [Alex] was able to create a timer activated by a loud noise, such as clapping. Once detected, the timer starts, flashing its LEDs to indicate time remaining. There’s also a nightlight feature, which activates when light levels decrease, making it easier to navigate the bathroom in the dark.

It’s a useful little project for these troubled times, and one that makes great use of everything onboard the Circuit Playground Express. Having everything included certainly does make projects come together quickly. You can even program it from your phone! Video after the break.

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Cellular Tracking Used During COVID-19 Pandemic

April 3, 2020 by 43 Comments

As most in the technology community know, nation states have a suite of powerful tools that can be used to trace and monitor mobile phones. By and large, this comes up in discussions of privacy and legislation now and then, before fading out of the public eye once more. In the face of a global pandemic, however, governments are now using these tools in the way many have long feared – for social control. Here’s what’s happening on the ground.

The Current Situation

With COVID-19 sweeping the globe, its high level of contagiousness and rate of hospitalizations has left authorities scrambling to contain the spread. Unprecedented lockdowns have been put in place in an attempt to flatten the curve of new cases to give medical systems the capacity to respond. A key part of this effort is making sure that confirmed cases respect quarantine rules, and isolate themselves to avoid spreading the disease. Rules have also been put in place in several countries where all overseas arrivals must quarantine, regardless of symptoms or status. Continue reading “Cellular Tracking Used During COVID-19 Pandemic” →