Crunching Giant Data From The Large Hadron Collider

May 14, 2020 by Moritz v. Sivers 19 Comments

Modern physics experiments are often complex, ambitious, and costly. The times where scientific progress could be made by conducting a small tabletop experiment in your lab are mostly over. Especially, in fields like astrophysics or particle physics, you need huge telescopes, expensive satellite missions, or giant colliders run by international collaborations with hundreds or thousands of participants. To drive this point home: the largest machine ever built by humankind is the Large Hadron Collider (LHC). You won’t be surprised to hear that even just managing the data it produces is a super-sized task.

Since its start in 2008, the LHC at CERN has received several upgrades to stay at the cutting edge of technology. Currently, the machine is in its second long shutdown and being prepared to restart in May 2021. One of the improvements of Run 3 will be to deliver particle collisions at a higher rate, quantified by the so-called luminosity. This enables experiments to gather more statistics and to better study rare processes. At the end of 2024, the LHC will be upgraded to the High-Luminosity LHC which will deliver an increased luminosity by up to a factor of 10 beyond the LHC’s original design value.

Currently, the major experiments ALICE, ATLAS, CMS, and LHCb are preparing themselves to cope with the expected data rates in the range of Terabytes per second. It is a perfect time to look into more detail at the data acquisition, storage, and analysis of modern high-energy physics experiments. Continue reading “Crunching Giant Data From The Large Hadron Collider” →

A Smart Bandage For Monitoring Chronic Wounds

May 12, 2020 by Orlando Hoilett 4 Comments

Here at Hackaday, we’re always enthralled by cool biohacks and sensor development that enable us to better study and analyze the human body. We often find ourselves perusing Google Scholar and PubMed to find the coolest projects even if it means going back in time a year or two. It was one of those scholarly excursions that brought us to this nifty smart bandage for monitoring wound healing by the engineers of FlexiLab at Purdue University. The device uses an omniphobic (hydrophobic and oleophobic) paper-based substrate coupled with an onboard impedance analyzer (AD5933), an electrochemical sensor (the same type of sensor in glucometers) for measuring uric acid and pH (LMP91000), and a 2.4 GHz antenna for wirelessly transmitting the data (nRF24L01). All this is programmed with an Arduino Nano. They even released their source code.

To detect uric acid, they used the enzyme uricase, which is very specific to uric acid and exhibits low cross-reactivity with other compounds. They drop cast uric acid onto a silver/silver chloride electrode printed on the omniphobic paper. Similarly, to detect pH, they drop cast a pH-responsive polymer called polyaniline emeraldine salt (PANI-ES) between two separate silver/silver chloride electrodes. All that was left was to attach the electrodes to the LMP91000, do a bit of programming, and there they were with their own electrochemical sensor. The impedance analyzer was a bit simpler to develop, simply attaching un-modified electrodes to the AD5933 and placing the electrodes on the wound.

The authors noted that the device uses a much simpler manufacturing process compared to smart bandages published by other academics, being compatible with large-scale manufacturing techniques such as roll-to-roll printing. Overcoming manufacturing hurdles is a critical step in getting your idea into the hands of consumers. Though they have a long way to go, FlexiLab appears to be on the right track. We’ll check back in every so often to see what they’re up to.

Until then, take a look at some other electric bandage projects on Hackaday or even make your own electrochemical sensor.

Open Source Raman Spectrometer Is Cheaper, But Not Cheap

May 12, 2020 by Al Williams 14 Comments

Raman spectrography uses the Raman scattering of photons from a laser or other coherent light beam to measure the vibrational state of molecules. In chemistry, this is useful for identifying molecules and studying chemical bonds. Don’t have a Raman spectroscope? Cheer up! Open Raman will give you the means to build one.

The “starter edition” replaces the initial breadboard version which used Lego construction, although the plans for that are still on the site, as well. [Luc] is planning a performance edition, soon, that will have better performance and, presumably, a greater cost.

Continue reading “Open Source Raman Spectrometer Is Cheaper, But Not Cheap” →

Measuring The Speed Of Light In 1927

May 8, 2020 by Al Williams 36 Comments

It is hard to remember that a lot of high tech research went on well before the arrival of electronic computers, lasers, and all the other things that used to be amazing but are now commonplace. That’s why we enjoyed [Michel van Biezen’s] two part post on how Michelson computed the speed of light in 1927. You can see the videos below.

Michelson wasn’t the first, of course. Galileo tried. He sent an assistant to the top of a hill with a lantern. When the assistant saw Galileo’s lantern, he was to uncover his lantern. They practiced near each other to account for reaction time. But when the assistant was 3 km away, it didn’t take any more time. The implication was that light traveled instantaneously, but, of course, it is actually just really fast.

By 1927, Michelson tried what was in effect the same technique but with better technology, and this time they put a reflector about 35 km away meaning the light had to go to the reflector and back for a total of about 70 km.

Continue reading “Measuring The Speed Of Light In 1927” →

Lego Microscope Does Research

May 5, 2020 by Al Williams 10 Comments

We’ve seen a lot of practical machines built using Lego. Why not? The bricks are cheap and plentiful, so if they can get the job done, who cares if they look like a child’s toy? Apparently, not [Yuksel Temiz]. He’s an engineer for IBM whose job involves taking pictures of microscopic fluidic circuits. When he wasn’t satisfied with the high-power $10,000 microscopes he had, he built his own. Using Lego. How are the pictures? Good enough to appear in many scientific journals.

Clearly, the microscope doesn’t just contain Lego, but it still came in at under $300. According to an interview from Futurism, the target devices are reflective which makes photographing them straight-on difficult. After experimenting with cameras on tripods, [Yuksel] decided he could build his own specialized device. You can see a video of the devices in question and some of the photographs below.

Continue reading “Lego Microscope Does Research” →

The Vaccine Factory Inside You: RNA Vaccine Basics

May 4, 2020 by Dan Maloney 19 Comments

As the world pulls back from the acute phase of the COVID-19 pandemic, it enters what will be perhaps a more challenging time: managing the long-term presence of the SARS-CoV-2 virus that causes the disease. In the roughly two-century history of modern vaccination practices, we’ve gotten pretty good at finding ways to protect ourselves from infectious diseases, and there’s little doubt that we’ll do the same for SARS-CoV-2. But developing a vaccine against any virus or bacterium takes time, and in a pandemic situation, time is exactly what’s at a premium.

In an effort to create an effective vaccine against this latest viral threat, scientists and physicians around the world have been taking a different approach to inoculation. Rather than stimulating the immune system in the usual way with a weakened sample of the virus, they’re trying to use the genetic material of the virus to stimulate an immune response. These RNA vaccines are a novel approach to a novel infection, and understanding how they work will be key to deciding whether they’ll be the right way to attack this pandemic.

Continue reading “The Vaccine Factory Inside You: RNA Vaccine Basics” →

Wolfram Physics Project Seeks Theory Of Everything; Is It Revelation Or Overstatement?

April 30, 2020 by Moritz v. Sivers 74 Comments

Stephen Wolfram, inventor of the Wolfram computational language and the Mathematica software, announced that he may have found a path to the holy grail of physics: A fundamental theory of everything. Even with the subjunctive, this is certainly a powerful statement that should be met with some skepticism.

What is considered a fundamental theory of physics? In our current understanding, there are four fundamental forces in nature: the electromagnetic force, the weak force, the strong force, and gravity. Currently, the description of these forces is divided into two parts: General Relativity (GR), describing the nature of gravity that dominates physics on astronomical scales. Quantum Field Theory (QFT) describes the other three forces and explains all of particle physics. Continue reading “Wolfram Physics Project Seeks Theory Of Everything; Is It Revelation Or Overstatement?” →