Day: March 1, 2025

A PCR machine with its side cover taken off exposing its guts, and the tray extended out

Making A PCR Machine Crypto Sign Its Results

March 1, 2025 by 2 Comments

Money, status, or even survival – there’s no shortage of incentives for faking results in the scientific community. What can we do to prevent it, or at least make it noticeable? One possible solution is cryptographic signing of measurement results.

Here’s a proof-of-concept from [Clement Heyd] and [Arbion Halili]. They took a ThermoFisher Scientific 7500 Fast PCR (Polymerase Chain Reaction) machine, isolated its daughter-software, and confined it into a pipeline that automatically signs each result with help of a HSM (Hardware Security Module).

A many machines do, this one has to be paired to a PC, running bespoke software. This one’s running Windows XP, at least! The software got shoved into a heavily isolated virtual machine running XP, protected by TEE (Trusted Execution Environment). The software’s output is now piped into a data diode virtual serial port out of the VM, immediately signed with the HSM, and signed data is accessible through a read-only interface. Want to verify the results’ authenticity? Check them against the system’s public key, and you’re golden – in theory.

This design is just a part of the puzzle, given a typical chain of custody for samples in medical research, but it’s a solid start – and it happens to help make the Windows XP setup more resilient, too.

Wondering what PCR testing is good for? Tons of things all over the medical field, for instance, we’ve talked about PCR in a fair bit of detail in this article about COVID-19 testing. We’ve also covered a number of hacker-built PCR and PCR-enabling machines, from deceivingly simple to reasonably complex!

Building A Nerf-like Rocket Launcher With Airburst Capability

March 1, 2025 by 4 Comments

Nerf blasters typically fire small foam darts or little foam balls. [Michael Pick] wanted to build something altogether more devastating. To that end, he created a rocket launcher with an advanced air burst capability, intended to take out enemies behind cover.

Unlike Nerf’s own rocket launchers, this build doesn’t just launch a bigger foam dart. Instead, it launches an advanced smart projectile that releases lots of smaller foam submunitions at a set distance after firing.

The rocket launcher itself is assembled out of off-the-shelf pipe and 3D printed components.  An Arduino Uno runs the show, hooked up to a Bluetooth module and a laser rangefinder. The rangefinder determines the distance to the target, and the Bluetooth module then communicates this to the rocket projectile itself so it knows when to release its foamy payload after launch. Releasing the submunitions is achieved with a small microservo in the projectile which opens a pair of doors in flight, scattering foam on anyone below. The rockets are actually fired via strong elastic bands, with an electronic servo-controlled firing mechanism.

We’ve featured some great Nerf builds over the years, like this rocket-blasting robot.

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