To say that the process of installing a magnetic resonance imager in a hospital is a complex task is a serious understatement. Once the approval of regulators is obtained, a process that could take years, architects and engineers have to figure out where the massive machine can be installed. An MRI suite requires a sizable electrical service to be installed, reinforced floors to handle the massive weight of the magnet, and special shielding in the walls and ceiling. And once the millions have been spent and the whole thing is up and running, there are ongoing safety concerns when working around a gigantic magnet that can suck ferromagnetic objects into it at any time.
MRI studies can reveal details of diseases and injuries that no other imaging modality can match, which justifies the massive capital investments hospitals make to obtain them. But what if MRI scanners could be miniaturized? Is there something inherent in the technology that makes them so massive and so expensive that many institutions are priced out of the market? Or has technology advanced far enough that a truly portable MRI?
It turns out that yes, an inexpensive MRI scanner is not only possible, but can be made portable enough to wheel into a patient care room. It’s not without compromise, but such a device could make a huge impact on diagnostic medicine and extend MRI technologies into places far beyond the traditional hospital setting.
Continue reading “Portable MRI Machine Comes To The Patient”
Hackers love to make music with things that aren’t normally considered musical instruments. We’ve all seen floppy drive orchestras, and the musical abilities of a Tesla coil can be ear-shatteringly impressive. Those are all just for fun, though. It would be nice if there were practical applications for making music from normally non-musical devices.
Thanks to a group of engineers at Case Western Reserve University in Cleveland, there is now: a magnetic resonance imaging machine that plays soothing music. And we don’t mean music piped into the MRI suite to distract patients from the notoriously noisy exam. The music is actually being played through the gradient coils of the MRI scanner. We covered the inner working of MRI scanners before and discussed why they’re so darn noisy. The noise basically amounts to Lorenz forces mechanically vibrating the gradient coils in the audio frequency range as the machine shapes the powerful magnetic field around the patient’s body. To turn these ear-hammering noises into music, the researchers converted an MP3 of [Yo Yo Ma] playing [Bach]’s “Cello Suite No. 1” into encoding data for the gradient coils. A low-pass filter keeps anything past 4 kHz from getting to the gradient coils, but that works fine for the cello. The video below shows the remarkable fidelity that the coils are capable of reproducing, but the most amazing fact is that the musical modification actually produces diagnostically useful scans.
Our tastes don’t generally run to classical music, but having suffered through more than one head-banging scan, a half-hour of cello music would be a more than welcome change. Here’s hoping the technique gets further refined.
Continue reading “Musical Mod Lets MRI Scanner Soothe The Frazzled Patient”
Why in the world does helium kill iPhones and other members of the Apple ecosystem? Enquiring minds want to know, and [Ben Krasnow] has obliged with an investigation of the culprit: the MEMS oscillator. (YouTube, embedded below.)
When we first heard about this, courtesy in part via a Hackaday post on MRI-killed iPhones, we couldn’t imagine how poisoning a micro-electromechanical system (MEMS) part could kill a phone. We’d always associated MEMS with accelerometers and gyros, important sensors in the smartphone suite, but hardly essential. It turns out there’s another MEMS component in many Apple products: an SiT 1532 oscillator, a tiny replacement for quartz crystal oscillators.
[Ben] got a few from DigiKey and put them through some tests in a DIY gas chamber. He found that a partial pressure of helium as low as 2 kPa, or just 2% of atmospheric pressure, can kill the oscillator. To understand why, and because [Ben] has a scanning electron microscope, he lapped down some spare MEMS oscillators to expose their intricate innards. His SEM images are stunning but perplexing, raising questions about how such things could be made which he also addresses.
The bottom line: helium poisons MEMS oscillators in low enough concentrations that the original MRI story is plausible. As a bonus, we now understand MEMS devices a bit better, and have one more reason never to own an iPhone.
Continue reading “[Ben Krasnow] Gasses MEMS Chips, For Science”
We live in a world where anyone can build a CT machine. Yes, anyone. It’s made of laser-cut plywood and it looks like a Stargate. Anyone can build an MRI machine. Of course, these machines aren’t really good enough for medical diagnosis, or good enough to image anything that’s alive for that matter. This project for the Hackaday Prize is something else, though. It’s biomedical imaging put into a package that is just good enough to image your lungs while they’re still in your body.
The idea behind Spectra is to attach two electrodes to the body (a chest cavity, your gut, or a simulator that’s basically a towel wrapped around the inside of a beaker). One of these electrodes emits an AC signal, and the second electrode measures the impedance and phase. Next, move the electrodes and measure again. Do this a few times, and you’ll be able to perform a tomographic reconstruction of the inside of a chest cavity (or beaker simulator).
Hardware-wise, Spectra uses more than two electrodes, thirty-two on the biggest version built so far. All of these electrodes are hooked up to a PCB that’s just under 2″ square, and everything is measured with 16-bit resolution at a 160 kSPS sample rate. To image something, each electrode sends out an AC current. Different tissues have different resistances, and the path taken through the body will have different outputs. After doing this through many electrodes, you can use the usual tomographic techniques to ‘see’ inside the body.
This is a remarkably inexpensive way to image the interior of the human body. No, it doesn’t have the same resolution as an MRI, but then again you don’t need superconducting electromagnets either. We’re really excited to see where this project will go, and we’re looking forward to the inevitable project updates.
You will no doubt have seen those videos where MRI machines suck up all sorts of metallic objects with hilariously disastrous results. The magnetic field in one of these machines can easily pull in metal objects from across the room, exerting a force of several hundred pounds on any ferrous object unlucky enough to wander too close. As you can probably imagine, designing mechanical devices that can operate in such an intense magnetic field is exceptionally difficult.
But this fully 3D printed pneumatic stepper motor designed by [Foad Sojoodi Farimani] might one day change that. The PneuAct, which he presented at the recent International Conference on Robotics and Automation (ICRA) in Brisbane, Australia, manages to run at up to 850 RPM with full position control using bursts of air rather than electronic pulses. Made entirely of plastic and without any electronic components, the PneuAct can not only operate in intense magnetic fields but also areas with flammable gases where sparks could potentially cause an explosion.
We often say that a design is “fully” 3D printable, even though it might require screws or other bits of hardware. But in the case of the PneuAct, it’s truly all printed. It has to be, or else the whole thing would be ripped apart when it got to close to the MRI machine. Each and every piece of the motor is printed in ABS, and can be used without any additional machining or cleanup. No lubrication is required, and [Foad] mentions that the whole thing is so cheap that it can be disposable. Which is a huge advantage in medical environments where contamination could be a concern.
Design-wise the PneuAct is essentially an expanded version of the 3D printed air motors we’ve seen previously, but it would be fair to say that none has ever been studied so closely before.
Continue reading “An MRI-Safe 3D Printed Pneumatic Stepper Motor”
Most posts here are electrical or mechanical, with a few scattered hacks from other fields. Those who also keep up with advances in biomedical research may have noticed certain areas are starting to parallel the electronics we know. [Dr. Rajib Shubert] is in one such field, and picked up on the commonality as well. He thought it’d be interesting to bridge the two worlds by explaining his research using analogies familiar to the Hackaday audience. (Video also embedded below.)
He laid the foundation with a little background, establishing that we’ve been able to see individual static neurons for a while via microscope slides and such, and we’ve been able to see activity of the whole living brain via functional MRI. These methods gradually improved our understanding of neurons, and advances within the past few years have reached an intersection of those two points: [Dr. Shubert] and colleagues now have tools to peer inside a functional brain, teasing out how it works one neuron at a time.
[Dr. Shubert]’s talk makes analogies to electronics hardware, but we can also make a software analogy treating the brain as a highly optimized (and/or obfuscated) piece of code. Virus stamping a single cell under this analogy is like isolating a single function, seeing who calls it, and who it calls. This pairs well with optogenetics techniques, which can be seen as like modifying a function to see how it affects results in real time. It certainly puts a different meaning on the phrase “working with live code”!
Continue reading “Reverse-Engineering Brains, One Neuron At A Time”
If you were to make a list of the most important technological achievements of the last 100 years, advanced medical imaging would probably have to rank right up near the top. The ability to see inside the body in exquisite detail is nearly miraculous, and in some cases life-saving.
Navigating through the virtual bodies generated by the torrents of data streaming out of something like a magnetic resonance imager (MRI) can be a challenge, though. This intuitive MRI slicer aims to change that and makes 3D walkthroughs of the human body trivially easy. [Shachar “Vice” Weis] doesn’t provide a great deal of detail about the system, but from what we can glean, the controller is based on a tablet and Vive tracker. The Vive is attached to the back of the tablet and detects its position in space. The plane of the tablet is then interpreted as the slicing plane for the 3D reconstruction of the structure undergoing study. The video below shows it exploring a human head scan; the update speed is incredible, with no visible lag. [Vice] says this is version 0.1, so we expect more to come from this. Obvious features would be the ability to zoom in and out with tablet gestures, and a way to spin the 3D model in space to look at the model from other angles.
Interested in how the machine that made those images works? We’ve covered the basics of MRI scanners before. And if you want to go further, you could always build your own.
Continue reading “Walking Through MRIs With A Vive”