Even On The Red Planet, Hexagons Are The Bestagons

Though their pure Platonic Forms may only exist in the world of ideas, certain regular shapes can’t help but keep falling out of natural processes– case in point, the six-sided solid we call a hexagon, which is indisputably the bestagon. Don’t take it up with us– start an argument with the God of War, because its his planet that’s showing off six sided features, dubbed “polygonal fractures” which NASA’s Curiosity rover is currently crushing under tread in Valle Grande. Now, you might look at the photos and say– well, that’s clearly a dried mudflat. Evidence of water! No brainier, let’s all get Nobel Prizes. Not so fast.

Nothing in nature is ever single-sourced or that simple; if you live somewhere you get dried mud, you may have seen such hexagonal features, but ask anyone from the land of the ice and snow and they’ll tell you that freeze-thaw or frost heave can bring a field of rigolith’s inner Catan board out as well. Sure, we usually call it “dirt” here on Earth, but it’s rigolith by any other name. So NASA isn’t jumping the gun, and their announcement conservatively says that they aren’t sure how the polygonal features formed. Which is both fair enough and very interesting, as figuring it out is going to give some clues into what was going on in this part of Mars in the geologically recent past, especially since this vast field of grid tiles stretches as far as the camera can see. The consensus is that Mars was once “warm and wet” but that’s a relative term– how warm, and how wet, are very much up for debate.

Speaking of crushing hexagons under Curiosity’s wheels– did anyone think said wheels would last this long? They were already tweaking the traction control to extend their life nine years ago. Between it’s plutonium power and ongoing software updates, its a fair bet that Curiosity will outlast the late, lamented Opportunity who currently holds the endurance record at 15 Earth-years.

High-Density Parchment Paper Papertronics With Laser-Carved Hydrophilic Channels

Paper as a substrate for electronic circuits is not very common, but promising for flexible circuits with low cost and easy recyclability. That said, paper is not an easy material to work with when printing traces, as the cellulose material is both absorbent and irregular, limiting the resolution and accuracy of so-called papertronics. Even when using higher-quality paper with wax-based masks this resulted in poor resolution issues, so [Zahra Rafiee] et al. opted to approach the problem from the other direction, by using hydrophobic parchment paper as the base combined with a laser.

The nice thing about the inks used with papertronics that they aren’t just traces, but can also be functional elements like resistors, which is also demonstrated in the paper. The channels for the inks are created using a 50 Watt CO2 laser, which etches away the silicone coating on the parchment paper. The achieved resolution in the article is around 250 µm for line widths and 300 µm line spacing, which is much better than that for wax-based alternatives.

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Rubidium Frequency Standard Explained

You’ve probably heard of rubidium frequency standards, which are used where you need an extremely accurate time or frequency reference. [IMSAI] guy has a good explainer video about what’s actually going on inside one of these standards. Much of the basic idea also applies to cesium standards.

The explainer starts with the periodic table. Rubidium and cesium are both alkali metals, with a single electron in their outermost electron shell. Rubidium has 37 electrons, with the outermost one relatively loosely bound. Naturally occurring rubidium consists mainly of two isotopes, rubidium-85 and rubidium-87, which have the same number of protons and electrons but different numbers of neutrons.

A rubidium standard typically has three gas cells that have a bit of rubidium in them. An RF-excited rubidium-87 discharge lamp produces light at very specific wavelengths. The RF energy excites rubidium atoms into higher electronic states, and when their electrons fall back to lower-energy states, the atoms emit photons.

That light passes through a filter cell containing rubidium-85. The filter preferentially absorbs part of the lamp’s spectrum, leaving light that optically pumps the rubidium-87 atoms in the second resonance cell into one of two closely spaced hyperfine states of the atom’s ground state.

Those two states differ because of the interaction between the magnetic moment of the outer electron and that of the rubidium-87 nucleus. Their energy separation corresponds to a microwave frequency of about 6.835 GHz.

The resonance cell is illuminated by the filtered light while also being exposed to microwave energy from a local oscillator. When the microwave frequency is exactly equal to the rubidium-87 hyperfine transition frequency, it transfers atoms between the two ground-state hyperfine levels. That changes how strongly the cell absorbs the optical pumping light, producing a detectable dip in the light reaching a photodetector.

Electronics then servo the microwave oscillator onto the center of that absorption dip, using a feedback technique somewhat analogous to a phase-locked loop. Once locked, the oscillator is effectively referenced to an atomic transition rather than to the dimensions or mechanical properties of a crystal, giving you an extremely stable frequency standard.

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Sketching Temporary Circuits With A Light-Triggered Floquet Topological Insulator

In semiconductor technology, a base material like silicon is permanently modified to induce certain electrical behavior. In comparison a topological insulator material could be used to create temporary circuits using something like light exposure. An example of this is the Floquet topological state, which has long been theorized, but is now claimed to have been demonstrated in SnTe semiconductor material, per a paper by [F. Chassot] et al. in Nature Physics.

The concept of topological insulators was first proposed in 1985, but proving their existence was hard. Recently photonic Floquet topological insulators (PFTIs) have gained interest, with experiments by [Qian Ma] et al. in 2025 as well as other teams confirming aspects of the theory.

This recent publication by [Chassot] et al. would thus confirm that optical control of topological insulators is thus possible. At the core of this effect is the band inversion that results from the light pulses, with the change in conduction being very brief, essentially for as long as the femtosecond pulses were maintained.

Although still very much in the fundamental research phase, the research on these electronic topological insulators offers an interesting look at potential new technologies, much like the field of photonic topological insulators does for photonics.

How The Vagus Nerve Promotes Healthy Cognition Via Acetylcholine Signaling

It’s been said for centuries that you cannot think on an empty stomach, and that love goes through the stomach. Although these may seem like merely cute jabs at the simplicity of human nature, recent research in rat models by [Logan Tierno Lauer] et al. indicates that the gut may be more influential in something as fundamental as memory formation and cognitive function than previously assumed.

Key to the gut-brain connection is the vagus nerve, an essential part of the autonomic nervous system that wires the brain into the body’s organs, including the gastrointestinal (GI) tract. It provides both sensory and motor fibers, so that the brain can literally sense the state of said GI tract, with various triggers as result. One of these is – as demonstrated in the paper – the release of acetylcholine (aCh) an important neurotransmitters in the CNS for cognitive functions including attention, memory and motivation.

Using in vivo fiber photometry it was found that during eating medial septum neurons released aCh, with various ways to impair this mechanism along the vagus nerve leading to this response disappearing. This also confirms earlier research that points the finger at a so-called early life Western Diet (WD) causing impaired memory and overall cognitive function, likely due this high fat and high sugar diet causing dysfunction in this aCh regulation mechanism.

Beyond once again reinforcing the need to eat healthily, this research also provides further insights in condition with declining cognitive function, such as Alzheimer’s and dementia.

De-Aging Human Tissue Using Special Enzyme To Remove AGEs

With human bodies being bags of mostly salty water and countless messy biochemical processes, it’s little wonder that over time some residues tend to collect in these systems. Although evolution has seen fit to also evolve a range of mechanisms to clean up many of those messes, some of these waste products are left to gather, such as advanced glycation end-products (AGEs). Implicated in everything from diabetes to chronic kidney disease and general aging-related conditions, recently researchers have developed a way to break down one type of these AGEs.

Called N(6)-Carboxymethyllysine (CML), there is evidence to suggest that the presence of AGEs like it in the extracellular matrix (ECM) has damaging effects on the ECM’s functioning, as observed in e.g. the inhibiting of collagen crosslinking and the resulting ‘aging’ of skin among other tissues. Essentially these waste product jam up the normal biochemical machinery, while also triggering pro-inflammatory factors.

Beyond aging-related conditions, this can result in a whole range of other diseases that may be resolved if these waste products could be cleaned out. To this end [Narisa Trabosh] et al. of the San Francisco-based Revel Pharmaceuticals laboratory created CMLase, an enzyme that breaks down CML.

Arterial tissue treated with the CMLase enzyme shows a clear difference. (Credit: Trabosh et al., Nature communications, 2026)
Arterial tissue treated with the CMLase enzyme shows a clear difference. (Credit: Trabosh et al., Nature communications, 2026)

The challenge here was to design this enzyme, which used a genetic selection approach in modified E. coli to narrow down suitable enzymes, optimized for dealing with free CML. Once they were fairly confident that they had a working enzyme, they had to test it and observe the results.

This testing was performed in model proteins in vitro, as well as in tissue samples from elderly donors. These latter included lens, skin and arterial tissue, all of which are long-lived tissues that have plenty of time to collect CML. After treatment with CMLase the presence of CML in these tissues was reduced by 55% for skin and 75% for arterial tissue.

Of course, as also noted in the article these are ex vivo experiments that do not yet directly translate to living patients. An initial human trial would need to show safety above all, even if the amount of waste produced by the clean-up of CML won’t be that significant.

Subsequent trials would need to demonstrate that such removal of CML leads to healthier tissues, which if confirmed would open the path for other pathogenic AGEs to get their own matching enzyme.

Filling High Pressure CO2 Tanks From Sugar Fermentation Gas

After previously using the fermenting of sugar to obtain ethanol fuel, [Hyperspace Pirate] figured that it’d be a waste to just blast the other half of the yeast production in the form of carbon dioxide into the air. This poses the slight problem that gaseous CO2 is fairly bulky, while compressing it into a liquid isn’t exactly for the faint of heart. This of course means that it’s a fun challenge, involving a beach ball, vapor-compression and various compressors.

Although at room temperature compressing CO2 into a liquid requires quite extreme pressures, if you lower it to freezing temperatures it becomes quite feasible to use more typical off-the-shell compressors.

In the video both oil-less and regular compressors are used, mostly because ultimately you want to get pure CO2 into the bottle, without oil or water. Here a few methods are explored, including a pre-cooler with the oil-less compressor as it cannot quite hit the same pressures. With a typical compressor linked to an oil-separator you can directly fill the tank, which is pretty nice, though even with this removal of water turned out to be a chore.

Desiccating the gas that comes out of the fermentation vat, is attempted using a converted water filter that’s filled with desiccant beads, but as the later tests show, this isn’t quite good enough to prevent moisture to make it into the bottle and clogging its nozzle. Of course, moisture here is more acceptable than oil for most applications, so with some more work this could be quite a feasible method to fill bottles with liquid CO2 for various nefarious applications like paintball guns and more.

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