Playing Snake With Digital Microfluidics

July 12, 2025 by Adam Zeloof 2 Comments

Display technology has come a long way since the advent of the CRT in the late 1800s (yes, really!). Since then, we’ve enjoyed the Nixie tubes, flip dots, gas plasma, LCD, LED, ePaper, the list goes on. Now, there’s a new kid on the block — water.

[Steve Mould] recently got his hands on an OpenDrop — an open-source digital microfluidics platform for biology research. It’s essentially a grid of electrodes coated in a dielectric. Water sits atop this insulating layer, and due to its polarized nature, droplets can be moved around the grid by voltages applied to the electrodes. The original intent was to automate experiments (see 8:19 in the video below for some wild examples), but [Steve] had far more important uses in mind.

When [Steve]’s €1,000 device shipped from Switzerland, it was destined for greatness. It was turned into a game console for classics such as Pac-Man, Frogger, and of course, Snake. With help from the OpenDrop’s inventor (and Copilot), he built paired-down versions of the games that could run on the 8×14 “pixel” grid. Pac-Man in particular proved difficult, because due to the conservation of mass, whenever Pac-Man ate a ghost, he grew and eventually became unwieldy. Fortunately, Snake is one of the few videogames that actually respects the laws of classical mechanics, as the snake grows by one unit each time it consumes food.

[Steve] has also issued a challenge — if you code up another game, he’ll run it on his OpenDrop. He’s even offering a prize for the first working Tetris implementation, so be sure to check out his source code linked in the video description as a starting point. We’ve seen Tetris on oscilloscopes and 3D LED matrices before, so it’s about time we get a watery implementation.

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Salamander Robot Is Squishy

April 8, 2025 by Al Williams 7 Comments

If you want to get started in microfluidic robotics, [soiboi soft’s] salamander is probably too complex for a first project. But it is impressive, and we bet you’ll learn something about making this kind of robot in the video below.

The pneumatic muscles are very impressive. They have eight possible positions using three sources of pressure. This seems like one of those things that would have been nearly impossible to fabricate in a home lab a few decades ago and now seems almost trivial. Well, maybe trivial isn’t the right word, but you know what we mean.

The soft robots use layers of microfluidic channels that can be made with a 3D printer. Watching these squishy muscles move in an organic way is fascinating. For right now, the little salamander-like ‘bot has a leash of tubes, but [soiboi] plans to make a self-contained version at some point.

If you want something modular, we’ve seen Lego-like microfluidic blocks. Or, grab the shrinky dinks.

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Microfluidic Motors Could Work Really Well For Tiny Scale Tasks

November 14, 2024 by Lewin Day 8 Comments

The vast majority of motors that we care about all stick to a theme. They rely on the electromagnetic dance between electrons and magnets to create motion. They come in all shapes and sizes and types, but fundamentally, they all rely on electromagnetic principles at heart.

And yet! This is not the only way to create a motor. Electrostatic motors exist, for example, only they’re not very good because electrostatic forces are so weak by comparison. Only, a game-changing motor technology might have found a way to leverage them for more performance. It achieves this by working with fluid physics on a very small scale.

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Tired With Your Robot? Why Not Eat It?

June 21, 2024 by Dave Rowntree 17 Comments

Have you ever tired of playing with your latest robot invention and wished you could just eat it? Well, that’s exactly what a team of researchers is investigating. There is a fully funded research initiative (not an April Fools’ joke, as far as we know) delving into the possibilities of edible electronics and mechanical systems used in robotics. The team, led by EPFL in Switzerland, combines food process engineering, printed and molecular electronics, and soft robotics to create fully functional and practical robots that can be consumed at the end of their lifespan. While the concept of food-based robots may seem unusual, the potential applications in medicine and reducing waste during food delivery are significant driving factors behind this idea.

The Robofood project (some articles are paywalled!) has clearly made some inroads into the many components needed. Take, for example, batteries. Normally, ingesting a battery would result in a trip to the emergency room, but an edible battery can be made from an anode of riboflavin (found in almonds and egg whites) and a cathode of quercetin, as we covered a while ago. The team proposed another battery using activated charcoal (AC) electrodes on a gelatin substrate. Water is split into its constituent oxygen and hydrogen by applying a voltage to the structure. These gasses adsorb into the AC surface and later recombine back into the water, providing a usable one-volt output for ten minutes with a similar charge time. This simple structure is reusable and, once expired, dissolves harmlessly in (simulated) gastric fluid in twenty minutes. Such a device could potentially power a GI-tract exploratory robot or other sensor devices.

But what use is power without control? (as some car tyre advert once said) Microfluidic control circuits can be created using a stack of edible materials, primarily oleogels, like ethyl cellulose, mixed with an organic oil such as olive oil. A microfluidic NOT gate combines a pressure-controlled switch with a fluid resistor as the ‘pull-up’. The switch has a horizontal flow channel with a blockage that is cleared when a control pressure is applied. As every electronic engineer knows, once you have a controlled switch and a resistor, you can build NOT gates and all the other logic functions, flip-flops, and memories. Although they are very slow, the control components are importantly edible.

Edible electronics don’t feature here often, but we did dig up this simple edible chocolate bunny that screams when you bite it. Who wouldn’t want one of those?

A line-art diagram of the microfluidic device. On the left, in red text, it says "Fibrillization trigger (CPB pH 5.0). There is a rectangular outline of the chip in grey, with a sideways trapezoid on the left side narrowing until it becomes an arrow on the right. At the right is an inset picture of the semi-transparent microfluidic chip and the text "Negative Pressure (Pultrusion)." Above the trapezoid is the green text "MaSp2 solution" and below is "LLPS trigger (CPB pH 7.0)" in purple. The green, purple, and red text correspond with inlets labeld 1, 2, and 3, respectively. Three regions along the arrow-like channel from left to right are labeled "LLPS region," "pH drop," and in a much longer final section "Fiber assembly region."

Synthetic Spider Silk

February 8, 2024 by Navarre Bartz 7 Comments

While spider silk proteins are something you can make in your garage, making useful drag line fibers has proved a daunting challenge. Now, a team of scientists from Japan and Hong Kong are closer to replicating artificial spider silk using microfluidics.

Based on how spiders spin their silk, the researchers designed a microfluidic device to replicate the chemical and physical gradients present in the spider. By varying the amount of shear and chemical triggers, they tuned the nanostructure of the fiber to recreate the “hierarchical nanoscale substructure, which is the hallmark of native silk self-assembly.”

We have to admit, keeping a small bank of these clear, rectangular devices on our desk seems like a lot less work than keeping an army of spiders fed and entertained to produce spider silk Hackaday swag. We shouldn’t expect to see a desktop microfluidic spider silk machine this year, but we’re getting closer and closer. While you wait, why not learn from spiders how to make better 3D prints?

If you’re interesting in making your own spider silk proteins, checkout how [Justin Atkin] and [The Thought Emporium] have done it with yeast. Want to make your spider farm spiders have stronger silk? Try augmenting it with carbon.

Discount Microfluidics From A $9 Spree At The Dollar Store

July 11, 2021 by Al Williams 1 Comment

Microfluidics — working with tiny volumes of fluids in tiny channels — isn’t something you’d think would be inexpensive. Unless you read [Alexander Bissells’] post on how he created microfluidic devices using stuff from the dollar store. The channels in these devices can be much smaller than a millimeter and the fluid volumes are sometimes measured in femtoliters. At those scales, fluids don’t work like we intuitively think they will.

The parts list included gel tape, baby droppers, and some assorted containers and tools. Total price at the dollar store $9. One of the key finds in the dollar store was some small spray bottles. They weren’t important themselves, but they contain small lengths of silicone tubing and that was useful. Plastic fresnel lenses along with the tubing and gel tape worked to make “chips.” The gel tape also gets cut to make the channels. An eyedropper with some modifications makes a reasonable syringe.

We aren’t sure what you can practically do with any of these, but the T-junction looked pretty interesting. If you want some ideas on how these devices work in biology, including COVID-19 testing, check out this article. And just last week [Krishna Sanka] hosted a Hack Chat on microfluidics in biohacking, you can find the transcript on the project page. If you need a pump, this one uses 3D printer firmware to control it.

Microfluidics For Biohacking Hack Chat

July 5, 2021 by Dan Maloney 2 Comments

Join us on Wednesday, July 7 at noon Pacific for the Microfluidics for Biohacking Hack Chat with Krishna Sanka!

“Microfluidics” sounds like a weird and wonderful field, but one that doesn’t touch regular life too much. But consider that each time you fire up an ink-jet printer, you’re putting microfluidics to work, as nanoliter-sized droplets of ink are spewed across space to impact your paper at exactly the right spot.

Ink-jets may be mundane, but the principles behind them are anything but. Microfluidic mechanisms have found their way into all sorts of products and processes, with perhaps the most interesting uses being leveraged to explore and exploit the microscopic realms of life. Microfluidics can be used to recreate some of the nanoscale biochemical reactions that go on in cells, and offer not only new ways to observe the biological world, but often to manipulate it. Microfluidics devices range from “DNA chips” that can rapidly screen drug candidates against thousands of targets, to devices that can rapidly screen clinical samples for exposure to toxins or pathogens.

There are a host of applications of microfluidics in biohacking, and Krishna Sanka is actively working to integrate the two fields. As an engineering graduate student, his focus is open-source, DIY microfluidics that can help biohackers up their game, and he’ll stop by the Hack Chat to run us through the basics. Come with your questions about how — and why — to build your own microfluidics devices, and find out how modern biohackers are learning to “go with the flow.”

Our Hack Chats are live community events in the Hackaday.io Hack Chat group messaging. This week we’ll be sitting down on Wednesday, July 7 at 12:00 PM Pacific time. If time zones have you tied up, we have a handy time zone converter.