Medical Hacks

703 Articles

Algae Gene Gives Blind Man Some Light-Based Sight

June 1, 2021 by 8 Comments

What are single-celled organisms good for, you may wonder? Science has found a wonderful new use for one of them — restoring partial sight to people with inherited forms of blindness. More specifically, they took a gene from algae that responds to light and moves toward it in order to replace dead or defective photo-receptor cells that lie between the human pupil and the optic nerve.

When light enters the eye, it triggers photo-receptor cells that in turn send signals to nerve cells called ganglions. These add information about motion and send the complete picture to the brain via the optic nerve. The researchers basically hacked the ganglion cells and turned them into photo-receptors. First they used a virus to get light-sensing molecules called chrimson into one of the retinas of the lone volunteer they’d managed to train before the pandemic. He’d been wearing the goggles out on walks and told them he could see the stripes of the crosswalk.

They were able to get him into the lab in summer 2020, where he donned a pair of goggles that register light changes and send amber light into the eye whenever that happens. He also wore a cap full of electrodes so the researchers could see what parts of his brain lit up when the goggles do their thing. With the goggles on and ready to fire, the man was able to distinguish whether a black cup was in front of him, and was even able to count multiple cups correctly most of the time. Although this is not a full restoration of vision, it’s an excellent development in that direction, and we’re excited to see where it goes.

In the future, the researchers hope to slim down the goggles into something more fashionable. Combine them with these camera-enabled shoes, and accessibility goes way up.

Thanks for the tip, [foamyguy]!

Self-Driving Or Mind Control? Which Do You Prefer?

May 24, 2021 by 9 Comments

We know you love a good biohack as much as we do, so we thought you would like [Tony’s] brainwave-controlled RC truck. Instead of building his own electroencephalogram (EEG), he thought he would use NeuroSky’s MindWave. EEGs are pretty complex, multi-frequency waves that require some fairly sophisticated circuitry and even more sophisticated signal processing to interpret. So, [Tony] thought it would be nice to off-load a bit of that heavy-lifting, and luckily for him, the MindWave headset is fairly hacker-friendly.

EEGs are a very active area of research, so some of the finer details of the signal are still being debated. However, It appears that attention can be quantified by measuring alpha waves which are EEG content between 8-10 Hz. And it seems as though eye blinks can be picked from the EEG as well. Conveniently, the MindWave exports these energy levels to an accompanying smartphone application which [Tony] then links to his Arduino over Bluetooth using the ever-so-popular HC-05 module.

To control the car, he utilized the existing remote control instead of making his own. Like most people, [Tony] thought about hooking up the Arduino pins to the buttons on the remote control, thereby bypassing the physical buttons, but he noticed the buttons were a bit smaller than he was comfortable soldering to and he didn’t want to risk damaging the circuit board. [Tony’s] RC truck has a pistol grip transmitter, which inspired a slightly different approach. He mounted the servo onto the controller’s wheel mechanism, allowing him to control the direction of the truck by rotating the wheel using the servo. He then fashioned another servo onto the transmitter such that the servo could depress the throttle when it rotates. We thought that was a pretty nifty workaround.

Cool project, [Tony]! We’ve seen some cool EEG Hackaday Prize entries before. Maybe this could be the next big one.

Continue reading “Self-Driving Or Mind Control? Which Do You Prefer?” →

Thought Control Via Handwriting

May 16, 2021 by 12 Comments

Computers haven’t done much for the quality of our already poor handwriting. However, a man paralyzed by an accident can now feed input into a computer by simply thinking about handwriting, thanks to work by Stanford University researchers. Compared to more cumbersome systems based on eye motion or breath, the handwriting technique enables entry at up to 90 characters a minute.

Currently, the feat requires a lab’s worth of equipment, but it could be made practical for everyday use with some additional work and — hopefully — less invasive sensors. In particular, the sensor used two microelectrode arrays in the precentral gyrus portion of the brain. When the subject thinks about writing, recognizable patterns appear in the collected data. The rest is just math and classification using a neural network.

If you want to try your hand at processing this kind of data and don’t have a set of electrodes to implant, you can download nearly eleven hours of data already recorded. The code is out there, too. What we’d really like to see is some easier way to grab the data to start with. That could be a real game-changer.

More traditional input methods using your mouth have been around for a long time. We’ve also looked at work that involves moving your head.

Building An Oxygen Concentrator: It Isn’t Rocket Science

May 10, 2021 by 41 Comments

Back at the start of the pandemic, a variety of hacker designs for life-saving machinery may have pushed the boundaries of patient safety. There are good reasons that a ventilator must pass extensive safety  testing and certification before it can be attached to a patient, because were it to in some way fail, the patient would die. A year later, we have many much safer and more realistic ways to use our skills as part of the effort.

Probably one of the most ambitious projects comes from a coalition of Indian hackerspaces who are adapting a proven oxygen concentrator for local manufacture. Among them is Hackaday’s own [Anool Mahidharia], who hosts a Maker’s Asylum video (embedded below) explaining how the oxygen concentrator works and how they can be made safely.

The team have proven their ability in manufacturing over the past year, here showing off the M19 motorised air purifying respirator.
The team have proven their ability in manufacturing over the past year, here showing off the M19 motorised air purifying respirator.

An oxygen concentrator is both surprisingly simple and imbued with a touch of magic. At its center are two columns of zeolite, a highly porous aluminosilicate mineral that performs the task of a molecular sieve. When air is pumped into the column, the zeolite traps nitrogen, leaving the oxygen-enriched remnant to be supplied onwards. There are two such columns to allow each to be on an alternate cycle of enrichment or purging to remove the accumulated nitrogen.

The point of the video is to show that such a device can be constructed from readily available parts and with common tools; as the title says it isn’t rocket science. Concentrators produced by the hackerspace coalition won’t save the world on their own, but as a part of the combined effort they can provide a useful and reliable source of oxygen that will make a significant difference in a country whose oxygen distribution network is under severe strain.

We previously covered the Indian oxygen concentrator effort when they launched the project. Their website can be found on the Maker’s Asylum website, and their crowdfunding campaign can be found on the Indian crowdfunding platform, Ketto. They have already proved their ability to coordinate large-scale manufacturing with their previous PPE and respirator projects, so please consider supporting them if you can. Meanwhile, we can’t help a twinge of space envy, from the fleeting glimpse of Maker’s Asylum in the video.

Continue reading “Building An Oxygen Concentrator: It Isn’t Rocket Science” →

ECG Project With All The Messy Safety Details

May 3, 2021 by 11 Comments

We’ve seen a number of heart rate monitoring projects on Hackaday, but [Peter’s] electrocardiography (ECG) Instructable really caught out attention.

If you’ve followed Hackaday for any period of time, you’re probably already somewhat familiar with the hardware needed to record the ECG. First, you need a high input impedance instrumentation amplifier to pick up the millivolt signal from electrical leads carefully placed on the willing subject’s body. To accomplish this, he used an AD8232 single-lead ECG module (we’ve actually seen this part used to make a soundcard-based ECG). This chip has a built-in instrumentation amplifier as well as an optional secondary amplifier for additional gain and low-pass filtering. The ECG signal is riddled with noise from mains that can be partially attenuated with a simple low-pass filter. Then, [Peter] uses an Arduino Nano to sample the output of the AD8232, implement a digital notch filter for added mains noise reduction, and display the output on a 2.8″ TFT display.

Other than the circuit itself, two things about his project really caught our attention. [Peter] walks the reader through all the different safety considerations for a commercial ECG device and applies these principles to his simple DIY setup to ensure his own safety. As [Peter] put it, professional medical electronics should follow IEC 60601. It’s a pretty bulky document, but the main tenets quoted from [Peter’s] write-up are:

  1. limiting how much current can pass through the patient
  2. how much current can I pass through the patient?
  3. what electrical isolation is required?
  4. what happens if a “component” fails?
  5. how much electromagnetic interference can I produce?
  6. what about a defibrillator?

[Peter] mentions that his circuit itself does not fully conform to the standard (though he makes some honest attempts), but lays out a crude plan for doing so. These include using high-valued input resistors for the connections to the electrodes and also adding a few protection diodes to the electrode inputs so that the device can withstand a defibrillator. And of course, two simple strategies you always want to follow are using battery power and placing the device in a properly shielded enclosure.

[Peter] also does a great job breaking down the electrophysiology of the heart and relates it to terms maybe a bit more familiar to non-medical professionals. Understanding the human heart might be a little less intimidating if we relate the heart to a simple voltage source like a battery or maybe even a function generator. You can imagine the ions in our cells as charger carriers that generate electrical potential energy and nerve fibers as electrical wires along which electrical pulses travel through the body.

Honestly, [Peter] has a wealth of information and tools presented in his project that are sure to help you in your next build. You might also find his ECG simulator code really handy and his low-memory display driver code helpful as well. Cool project, [Peter]!

Measuring ECG is something that is near and dear to my heart (sorry, couldn’t resist). Two of my own projects that were featured on Hackaday before I became a writer here include a biomedical sensor suite in Arduino shield form factor, and a simple ECG built around an AD623 instrumentation amplifier.

An LED Heartbeat Display You Can Wear On Your Sleeve

April 30, 2021 by 3 Comments

There are a few different ways to take a person’s pulse, with varying utility depending on the categories said patient fits in to. [Nitin Nair]’s method doesn’t really have a medical application, but it’s certainly a neat example of what you can do with modern sensors. 

The build combines an EmotiBit sensor platform with an Adafruit Feather and accompanying Charlieplexed LED module. The EmotiBit packs a PPG, or photoplethysmogram sensor, otherwise known as a pulse oximeter, which uses optical methods to detect changes in blood volume beneath the skin. From this data, a pulse rate can be derived, and the LEDs flashed with a heart graphic in concert with the rhythm of the wearer’s heart. The benefit of the PPG in the EmotiBit is that it can be worn on the wearer’s arm, or other location with suitable vascularization. This allows the wearer to place the sensor on the arm, and thus wear their heart on their sleeve.

It’s a cool concept, and we’d love to see it neatly packaged with a smoothly animated fade as a sports accessory. It’d be an easy way to signal how fast your heart rate recovers on a run with friends – the device could brag about your fitness for you. Alternatively, if pulse oximetry isn’t enough for you, go ahead and build an ECG instead!