Genetically Modified Mosquitos: Biohacking For Disease Prevention

Many years ago, I took a summer trip to the Maryland shore with some friends. One of my buddies and I got bored with playing football on the beach, so we decided to take a hike on one of the many trails back into the wooded area behind the dunes. At the trailhead we noticed a prominent sign, warning about the presence of “very aggressive mosquitos” and not to enter without first applying ample insect repellent. We scoffed at the warning as only young idiots could and soldiered on, bare-legged and confident that we’d be fine.

About three minutes into our hike, a small group came pelting down the trail in a panic. “It’s true! Turn back!” they shouted as they flew past us. Undeterred, or at least unwilling to appear that way to each other, we pressed on, only to discover a few minutes later that we were making a substantial blood sacrifice to the next generation of mosquitos on Assateague Island. We couldn’t bear more than a few seconds before turning tail and running back to the beach and jumping into the ocean to get rid of the last few dozen bloodsuckers.

I learned a valuable lesson from that experience, as well as developing a deep and abiding hatred of mosquitos. It turns out I’m in good company — pretty much everyone hates mosquitos, which are not just a nuisance but can be downright dangerous to be around. But if tests with genetically engineered mosquitos currently underway in Florida turn out well, we may be able to finally turn the tide against mosquito-borne diseases, simply by killing all the females before they ever reach adulthood.

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Ingenuity Completes Fourth Flight On Mars, Gets A New Mission

It’s the same on Mars as it is here — just when you’re getting used to your job, the bosses go and change things up.

At least that’s our read on the situation at Jezero crater, where the Mars Ingenuity helicopter has just had its mission upgraded and extended. In a Friday morning press conference, the Ingenuity flight team, joined by members of the Perseverance team and some NASA brass, made the announcement that Ingenuity had earned an extra 30 sols of flight time, and would be transitioned from a mere “technology demonstrator” to an “operations demonstration” phase. They also announced Ingenuity’s fourth flight, which concluded successfully today, covering 266 meters and staying airborne for 117 seconds.

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Look Out Below! China’s Heavy-Lift Rocket Due For Uncontrolled Reentry Within Days

On April 28th, China successfully put the core module of their Tianhe space station into orbit with the latest version of the Long March 5B heavy-lift booster. This rocket, designed for launching large objects into low Earth orbit, is unique in that the 33.16 m (108.8 ft) first stage carries the payload all the way to orbit rather than separating at a lower altitude. Unfortunately, despite an international effort to limit unnecessary space debris, the first stage of the Long March 5B booster is now tumbling through space and is expected to make an uncontrolled reentry sometime in the next few days.

The massive booster has been given the COSPAR ID 2021-035-B, and ground tracking stations are currently watching it closely to try and determine when and where it will reenter the Earth’s atmosphere. As of this writing it’s in a relatively low orbit of 169 x 363 km, which should decay rapidly given the object’s large surface area. Due to the variables involved it’s impossible to pinpoint where the booster will reenter this far out, but the concern is that should it happen over a populated area, debris from the 21 metric ton (46,000 pound) booster could hit the ground.

The Tianhe core module.

This is the second launch for the Long March 5B, the first taking place on May 5th of 2020. That booster was also left in a low orbit, and made an uncontrolled reentry six days later. During a meeting of the NASA Advisory Council’s Regulatory and Policy Committee, Administrator Jim Bridenstine claimed that had the rocket reentered just 30 minutes prior, debris could have come down over the continental United States. Objects which were suspected of being remnants of the Long March 5B were discovered in Africa, though no injuries were reported.

China’s first space station, Tiangong-1, made an uncontrolled reentry of its own back in 2018. It’s believed that most of the 8,500 kg (18,700 lb) burned up as it streaked through the atmosphere, and anything that was left fell harmlessly into the South Pacific Ocean. While small satellites are increasingly designed to safely disintegrate upon reentry, large objects such as these pose a more complex problem as we expand our presence in low Earth orbit.

Mice Develop Inside An Artificial Womb

Well, it looks like those fetus fields from The Matrix (1999) just became a little bit more plausible. Although people-growing is probably a long way off, mice can now mostly develop inside an artificial uterus (try private window if you hit a paywall) thanks to a breakthrough in developmental biology. So far, the mice can only be kept alive halfway through gestation. There’s a point at which the nutrient formula provided to them isn’t enough, and they need a blood supply to continue growing. That’s the next goal. For now, let’s talk about that mechanical womb setup.

Carousel of Care

The mechanical womb was developed to better understand how various factors such as gene mutations, nutrients, and environmental conditions affect murine fetuses in development. Why do miscarriages occur, and why do fertilized eggs fail to implant in the first place? How exactly does an egg explode into 40 trillion cells when things do work out? This see-through uterus ought to reveal a few more of nature’s gestational secrets.

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Airports Are Now AirBNBs For Honeybees

In the summer of 2012, honeybees swarmed the Pittsburgh airport, probably because the conditions are favorable there. Like many airports, the tarmac is surrounded by wild, wide-open fields that exist to contain the cacophony. And a couple of nearby creeks are dotted with plenty of forage-worthy wildflowers.

Free honey? Wúnderbar!

Now, nearly a decade later, the airport is home to 110 colonies that house around 4 million honeybees. And they aren’t alone. Several other US airports are getting in on the apiary action, including O’Hare, Sea-Tac, and Minneapolis-St. Paul.

The relationship between honeybees and airports is a symbiotic one — the honey the bees produce is a litmus test for air pollution levels around the airport, which must fall within regulations. German airports have employed bees as ‘bio-detectives’ for over twenty years, and they give the honey away for free inside the terminal. It’s okay, though — analysis reveals that the hydrocarbon and heavy metal levels in the airport honey aren’t any higher than honey from non-industrial bees.

Given that honeybees pollinate around $15 billion in crops annually in the US alone, it’s a wonder that we aren’t doing everything possible to fight colony collapse disorder and other problems around the world. This mysterious issue has grown in the last few years, and 2020 saw highest death toll since 2016. Colony collapse disorder aside, plenty of problems persist for our fuzzy friends — pests, pesticides, pathogens, and poor nutrition.

What’s the deal with bees, anyway? How do they fly? Because they aren’t supposed to fly.

This Week In Security: Dan Kaminsky, Banned From Kernel Development, Ransomware, And The Pentagon’s IPv4 Addresses

This week we’re starting off with a somber note, as Dan Kaminsky passed at only 42, of diabetic ketoacidosis. Dan made a name for himself by noticing a weakness in DNS response verification that could allow attackers to poison a target DNS resolver’s cache. A theoretical attack was known, where spoofed DNS responses could collide with requests, but Time-To-Live values meant that DNS requests only go out once per eight hours or so. The breakthrough was realizing that the TTL limitation could be bypassed by requesting bogus subdomains, and aiming the spoofed responses at those requests. This simple technique transformed a theoretical attack that would take 87 years to a very real 10 second attack. Check out the period video after the break, where Dan talked about his efforts in getting the problem fixed.
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Solar And Wind Could Help Support Ethiopia’s Grand Dam Project

Ethiopia is in the midst of a major nation-building project, constructing the Grand Ethiopian Renaissance Dam (GERD). Upon completion, GERD will become the largest hydropower plant in Africa, providing much needed electricity for the country’s growing population.

The project dams the Blue Nile, a river which later flows into neighbouring Sudan, where it merges with the White Nile and then flows on to Egypt. Like all rivers that flow across political boundaries, concerns have been raised about the equitable management of the water resources to the benefit of those upstream and down. Too much water dammed upstream in GERD could have negative effects on Egyptian agriculture reliant on river flows, for example. Efforts are ongoing to find a peaceful solution that suits all parties. Recently, suggestions have been made to supplement the dam’s power output with solar and wind to minimise disruption to the river’s users.

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