Stirring Up 3D-Printed Lab Equipment

July 9, 2023 by Bryan Cockfield 18 Comments

Magnetic stirrers are a core part of many chemistry labs. They offer many advantages for ensuring the effective mixing of solutions compared to other methods of stirring, including consistency, precise control, operation within closed systems, and of course, hands-free automatic operation. With so many reasons for employing a magnetic stirrer, it’s not too surprising that [Joey] would want one. He built his using 3D-printed parts rather than purchasing it.

The magnetic stirrer uses a 3D-printed enclosure for the base. Inside is a PWM controller which sends power to a small DC motor. A 3D-printed arm is attached to the motor, which hosts a pair of magnets. As the arm spins inside the enclosure, the magnetic fields from the magnet couple with the stir bar inside the mixture, allowing it to spin without any mechanical link to the stirring device and without any input from the user. [Joey] has also made all the 3D-printed parts for this build available on Printables.

While magnetic stirrers aren’t the most complicated of devices (or the most expensive), building tools like this anyway often has other advantages, such as using parts already on hand, the ability to add in features and customizations that commercial offerings don’t have, or acting as a teaching aid during construction and use. It’s also a great way to put the 3D printer to work, along with this other piece of 3D-printed lab equipment designed for agitating cell cultures instead.

3D Printed Gadgets Make Lab Work Easier

December 15, 2022 by Lewin Day 1 Comment

If you’ve worked in a bio or chem lab, you’ve probably found yourself handling all manner of plastic. Test tubes, fixtures, clamps — there’s a cavalcade of this stuff that fattens up the order books of lab suppliers every quarter. Sometimes, though, the commercial solutions aren’t quite what you need. For [AtomicVirology], the solution was to 3D print custom lab accessories to make work easier.

The tube adapter allows the collection of 60 small samples without having to unload the fraction collector halfway through. That’s a big quality-of-life improvement for staffers using the equipment.

Some of the devices are straightforward, like simple holders for upright storage of centrifuge tubes. Others are fun twists on the theme, like the Millennium Falcon tube holder or one shaped like the Imperial Star Destroyer. Meanwhile, a resuable plastic tube cover serves as a way to protect tubes from light without the fuss of covering them in aluminium foil. It’s less wasteful, too!

Our favorite, though, is a simple adapter for holding fraction tubes in a AKTA fraction collection device. Stock, the AKTA device will hold 30 small tubes in the inside ring, and 30 larger tubes in the outside ring. Thanks to a simple printed part, though, it can be modified to hold 60 tubes of the smaller size. This allows the collection of 60 small fractions in a shorter period of time simply by moving the delivery head from the inner to the outer ring, without having to swap out 30 tubes halfway through a chromatography column, for example.

It goes to show that a 3D printer is good for more than just churning out Pikachus. It’s a Swiss Army knife for solving fiddly little problems without having to rely on some company to injection-mold you 10,000 examples of whatever it is you want. Of course, if you do want to injection mold something, we’ve covered how to do that before, as well.

3D Printer Repurposed For Light-Duty Lab Automation Tasks

November 11, 2022 by Dan Maloney 3 Comments

Laboratory automation equipment is expensive stuff, to such a degree that small labs are often priced out of the market. That’s a shame, because there are a lot of tedious manual tasks that even modest labs would benefit from automating. Oh well — that’s what grad students are for.

But it actually isn’t that hard to bring a little automation to the lab, if you follow the lead of [Marco], [Chinna], and [Vittorio] and turn a 3D printer into a simple lab robot. That’s what HistoEnder is — a bog-standard Creality Ender 3 with a couple of special modifications that turn it into a tool for automating histology slide preparation. Histology is the study of the anatomy of tissues and uses various fixing and staining techniques to make microscopic features visible. In practice, this means moving baskets of glass slides back and forth between jars of different solutions, a job that’s perfect for a simple Cartesian gantry lab robot with a small work envelope and light loads.

None of the printer modifications are permanent; the 3D printed accessories — a hook for the slide basket and a carrier for standard histology staining jars — can quickly come off the printer to return it to its regular duty. All it takes to run HistoEnder is a bit of custom G-code and some careful alignment of the jar carrier on the print bed. We suppose the bed heater could even be used to warm up the fixing and staining solutions. There’s a brief video of HistoEnder in action embedded in the tweet below.

This isn’t the first time this team has repurposed technology for the lab — remember the fitness band that was turned into an optical densitometer?

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Tube Tumbler Provides The Perfect Culture

March 27, 2022 by Brian McEvoy 2 Comments

We’ve all had to shake jars of nail polish, model paint, or cell cultures. Mixing paint is easy – but bacteria and cells need to be agitated for hours. Happily, laboratory tube tumblers automate this for us. The swishing action is handled with rotation. The vials are mounted at angles around a wheel. The angular offset means the tubes are inclined as they rise, and declined as they fall. This causes the liquid in the tube to slosh from one side to the other as the wheel rotates. [Sebastian S. Cocioba] aka [ATinyGreenCell] released his plans through Tinkercad and GitHub, and with a name like Sir Tumbalot, we know he must be cultured indeed.

Grab your monocles. Version 2 features a driven wheel lined with magnets to attach tube adapters, and he’s modeled 50mL and twin 15mL tube holders. The attachment points look like a simple beveled rectangle with a magnet pocket, so if you’re feeling vigorous for vials, you can whip up custom sockets and tumble any darn thing. A Trinamic StealthChop chip on a custom PCB controls the pancake stepper, and the whole shebang should cost less than $50USD. We’re wondering what other purposes this modular design could have, like the smallest rock tumbler or resin print rinser.

Making lab equipment is phenomenal for saving money for things that just spin up to a biotech lab.

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Spectrometer Is Inexpensive And Capable

February 9, 2019 by Brian McEvoy 14 Comments

We know the effect of passing white light through a prism and seeing the color spectrum that comes out of the other side. It will not be noticeable to the naked eye, but that rainbow does not fully span the range of [Roy G. Biv]. There are narrowly absent colors which blur together, and those missing portions are a fingerprint of the matter the white light is passing through or bouncing off. Those with a keen eye will recognize that we are talking about spectrophotometry which is identifying those fingerprints and determining what is being observed and how much is under observation. The device which does this is called a spectrometer and [Justin Atkin] invites us along for his build. Video can also be seen below.

Along with the build, we learn how spectrophotometry works, starting with how photons are generated and why gaps appear in the color spectrum. It is all about electrons, which some of our seasoned spectrometer users already know. The build uses a wooden NanoDrop style case cut on a laser engraver. It needs some improvements which are mentioned and shown in the video so you will want to have some aluminum tape on hand. The rest of the bill of materials is covered including “Black 2.0” which claims to be the “mattest, flattest, black acrylic paint.” Maybe that will come in handy for other optical projects. It might be wise to buy first surface mirrors cut to size, but you can always make bespoke mirrors with carefully chosen tools.

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Biology Lab On Your Christmas List

December 11, 2018 by Brian McEvoy 6 Comments

We hope you have been good this year because we have a list to start your own biology lab and not everything will fit into Santa’s bag (of holding). If you need some last minute goodie points, Santa loves open-source and people who share on our tip line. Our friends at [The Thought Emporium] have compiled a list of the necessary equipment for a biology lab. Chemistry labs-in-a-box have been the inspiration for many young chemists, but there are remarkable differences between a chemistry lab and a biology lab which are explained in the Youtube video linked above and embedded after the break.

If you are preparing to start a laboratory or wondering what to add to your fledging lab, this video is perfect. It comes from the perspective of a hacker not afraid to make tools like his heat block and incubator which should absolutely be built rather than purchased but certain things, like a centrifuge, should be purchased when the lab is mature. In the middle we have the autoclave where a used pressure cooker may do the trick or you may need a full-blown commercial model with lots of space and a high-pressure range.

Maybe this will take some of the mystique out of starting your own lab and help you understand what is happening with a gel dock or why a spectrophotometer is the bee’s knees. There are a handful of other tools not mentioned here so if this is resonating, it will be worth a watch.

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Open Source Laboratory Rocker Is Super Smooth

July 20, 2018 by Donald Papp 19 Comments

Lab equipment is often expensive, but budgets can be tight and not always up to getting small labs or researchers what they need. That’s why [akshay_d21] designed an Open Source Lab Rocker with a modular tray that uses commonly available hardware and 3D printed parts. The device generates precisely controlled, smooth motion to perform automated mild to moderately aggressive mixing of samples by tilting the attached tray in a see-saw motion. It can accommodate either a beaker or test tubes, but since the tray is modular, different trays can be designed to fit specific needs.

Source code and schematics are available from [akshay_d21]’s Google Drive and the 3D models are also available from the National Institute of Health’s 3D Print Exchange. A demonstration video is embedded below, in which you can see how smooth and controlled the motions are.

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