Shockingly, DARPA’s Brain Stimulator Might Not Be Complete Nonsense

Where does your mind jump when you hear the mention of electroshock therapy? The use of electrical current to treat various medical conditions has a long and controversial history. Our fascination with the medical applications of electricity have produced everything from the most alarming of patent medicines to life-saving devices like pacemakers and the Automatic External Defibrillator.

The oldest reference I could find is the use of the torpedo fish to allegedly cure headaches, gout, and so on in 43 CE. Incidentally, Torpedo torpedo is an awesome species name.

Dosage: Apply live fish as needed to face? Source

Much more recently, there has been interest in transcranial direct current stimulation (tDCS). In essence, it’s a technique by which you pass an electrical current (typically about 2 milliamps) between strategically positioned electrodes on your head. The precise reason to do this is a bit unclear; different journal articles have suggested improvements in cognition, learning, and/or the potential treatment of various diseases.

I think most of us here spend a lot of time studying. The idea that a simple, noninvasive device can accelerate that is very attractive. We’ve covered a few people building their own such devices.

Unfortunately, what we want to be true is irrelevant. Superficially, this looks like a DARPA-funded panacea with no clearly established mechanism of action. Various commercial products are being sold that imply (but as usual, don’t directly state) that tDCS is useful for treating pretty much everything, with ample use of ‘testimonials’.

While tDCS can be prescribed by a physician in some countries to complement a stroke rehabilitation regime, for off-label purposes you may as well just go apply a fish to your face. Let’s dig into the literature and products that are out there and see if we can find the promise hiding amidst the hype.

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How Pure Is This Cup Of Joe? Coffee, Conspiracy, And Citizen Science

Have you ever thought about coffee purity? It’s more something you’d encounter with prescription or elicit drugs, but coffee is actually a rather valuable commodity. If a seller can make the actual grounds go a bit further by stretching the brew with alternative ingredients there becomes an incentive to cheat.

If this sounds like the stuff rumors are made of, that’s because it is! Here in Ho Chi Minh City there are age-old rumors a coffee syndicate that masterfully passes off adulterated product as pure, high-grade coffee. Rumors are one thing, but the local media started picking up on these suspicions and that caught my attention. I decided to look to simple chemistry to see if I could prove or disprove the story.

What we want to investigate is whether price and coffee purity are related. If they are, then after accounting for the effect of price, we will want to know whether proximity to the market where artificial coffee flavoring is sold has an effect on coffee purity.

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Yellowing: The Plastic Equivalent Of A Sunburn

Your fancy white electronic brick of consumer electronics started off white, but after some time it yellowed and became brittle. This shouldn’t have happened; plastic is supposed to last forever. It turns out that plastic enclosures are vulnerable to the same things as skin, and the effects are similar. When they are stared at by the sun, the damage is done even though it might not be visible to you for quite some time.

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Beyond Conway: Cellular Automata From All Walks Of Life

There’s a time in every geek’s development when they learn of Conway’s Game of Life. This is usually followed by an afternoon spent on discovering that the standard rule set has been chosen because most of the others just don’t do interesting things, and that every idea you have has already been implemented. Often enough this episode is then remembered as ‘having learned about cellular automata’ (CA). While important, the Game of Life is not the only CA out there and it’s not even the first. The story starts decades before Life’s publication in 1970 in a place where a lot of science happened at that time: the year is 1943, the place is Los Alamos in New Mexico and the name is John von Neumann.

Recap: What is a CA?

A cyclic CA making some waves

The ‘cellular’ part in the name comes from the fact that CAs represent a grid of cells that can be in a number of defined states. The grid can have any number of dimensions, but with three dimensions the visual representation starts to get into the way, and above that most human brains stop working, so two-dimensional grids are the most common — with the occasional one-dimensional surprise. The cells’ states are in most cases discrete but a subset of continuous CAs exists. During the operation of a CA the future state of every cell in the grid is determined from each cells state according to a set of rules which in most cases take into account the states of neighboring cells.

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Coffee, Conspiracy, And Citizen Science: An Introduction To Iodometry

I take coffee very seriously. It’s probably the most important meal of the day, and apparently the largest overall dietary source of antioxidants in the United States of America. Regardless of whether you believe antioxidants have a health effect (I’m skeptical), that’s interesting!

Unfortunately, industrially roasted and ground coffee is sometimes adulterated with a variety of unwanted ‘other stuff’: corn, soybeans, wheat husks, etc. Across Southeast Asia, there’s a lot of concern over food adulteration and safety in general, as the cost-driven nature of the market pushes a minority of vendors to dishonest business practices. Here in Vietnam, one of the specific rumors is that coffee from street vendors is not actually coffee, but unsafe chemical flavoring agents mixed with corn silk, roasted coconut husks, and soy. Local news reported that 30% of street coffee doesn’t even contain caffeine.

While I’ve heard some pretty fanciful tales told at street side coffee shops, some of them turned out to be based on some grain (bean?) of truth, and local news has certainly featured it often enough. Then again, I’ve been buying coffee at the same friendly street vendors for years, and take some offense at unfounded accusations directed at them.

This sounds like a job for science, but what can we use to quantify the purity of many coffee samples without spending a fortune? As usual, the solution to the problem (pun intended) was already in the room:

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Surfboard Industry Wipes Out, Innovation Soon Follows

For decades, Gordon Clark and his company Clark Foam held an almost complete monopoly on the surfboard blank market. “Blanks” are pieces of foam with reinforcing wood strips (called “stringers”) in a rough surfboard shape that board manufacturers use to make a finished product, and Clark sold almost every single one of these board manufacturers their starting templates in the form of these blanks. Due to environmental costs, Clark suddenly shuttered his business in 2005 with virtually no warning. After a brief panic in the board shaping industry, and a temporary skyrocketing in price of the remaining blanks in existence, what followed next was rather surprising: a boom of innovation across the industry.

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Reverse Polish Notation And Its Mildly Confusing Elegance

The best rummage sale purchase I ever made was a piece of hardware that used Reverse Polish Notation. I know what you’re thinking… RPN sounds like a sales gimmick and I got taken for a fool. But I assure you it’s not only real, but a true gem in the evolution of computing.

Best rummage sale find ever!
Best rummage sale find ever!

Sometime in the 1980s when I was a spotty teen, I picked up a calculator at a rummage sale. Protected by a smart plastic case, it was a pretty good condition Sinclair Scientific that turned out when I got it home to have 1975 date codes on its chips, and since anything with a Sinclair badge was worth having it became mine for a trifling amount of money. It had a set of corroded batteries that had damaged one of its terminals, but with the application of a bit of copper strip I had a working calculator.

And what a calculator! It didn’t have many buttons at a time when you judged how cool a scientific calculator was by the prolific nature of its keyboard. This one looked more akin to a run-of-the-mill arithmetic calculator, but had button modes for trigonometric functions and oddly an enter key rather than an equals sign. The handy sticker inside the case explained the mystery, this machine used so-called Reverse Polish Notation, or RPN. It spent several years on my bench before being reverently placed in a storage box of Sinclair curios which I’ve spent half a day turning the house over to find as I write this article.

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