Cyborg Mushrooms

Of all the fictional cyborgs who turn against humanity to conquer the planet, this is as far from that possibility as you can get. These harmless mushrooms seem more interested in showing off their excellent fashion sense with a daring juxtaposition of hard grid lines with playful spirals. But the purpose of this bacteria-fungus-technology hybrid is to generate electricity. The mushrooms are there to play nurse to a layer of cyanobacteria, the green gel in the photo, while the straight black lines harvest electricity.

Cyanobacteria do not live very long under these kinds of conditions, so long-term use is out of the question, but by giving the cyanobacteria somewhere it can thrive, the usefulness grows. The interplay between bacterial and supportive organics could lead to advances in sensors and hydrogels as well. At some point, we may grow some of our hardware and a green thumb will be as useful as a degree in computer science.

Hydrogels could be the next medical revolution, and we’ve already made hydrogels into tattoos, used them as forms for artificial muscles, and hydrogels can be a part of soft tissue printing.

Alice Evans: Brucellosis, Or Why We Pasteurize Milk

It’s easy to forget how much illness and death was caused by our food and drink just one hundred years ago. Our modern food systems, backed by sound research and decent regulation, have elevated food safety to the point where outbreaks of illness are big news. If you get sick from a burger, or a nice tall glass of milk, it’s no longer a mystery what happened. Instead we ask why, and “who screwed up?”

In the early 20th century though, many food-borne illnesses were still a mystery, and microbiology was a scientific endeavor that was just getting started. Alice Catherine Evans was an unlikely figure to make a dent in this world at the time, but through her research at the United States Department of Agriculture’s (USDA), and later at the Hygienic Laboratory (now the National Institute of Health) she had a huge impact on the field of bacteriology, the dairy industry, and consumer safety. Continue reading “Alice Evans: Brucellosis, Or Why We Pasteurize Milk”

Hacked Heating Instruments For The DIY Biology Lab

[Justin] from The Thought Emporium takes on a common molecular biology problem with these homebrew heating instruments for the DIY biology lab.

The action at the molecular biology bench boils down to a few simple tasks: suck stuff, spit stuff, cool stuff, and heat stuff. Pipettes take care of the sucking and spitting, while ice buckets and refrigerators do the cooling. The heating, however, can be problematic; vessels of various sizes need to be accommodated at different, carefully controlled temperatures. It’s not uncommon to see dozens of different incubators, heat blocks, heat plates, and even walk-in environmental chambers in the typical lab, all acquired and maintained at great cost. It’s enough to discourage any would-be biohacker from starting a lab.

[Justin] knew It doesn’t need to be that way, though. So he tackled two common devices:  the incubator and the heating block. The build used as many off-the-shelf components as possible, keeping costs down. The incubator is dead simple: an insulated plastic picnic cooler with a thermostatically controlled reptile heating pad. That proves to be more than serviceable up to 40°, at the high end of what most yeast and bacterial cultures require.

The heat block, used to heat small plastic reaction vessels called Eppendorf tubes, was a little more complicated to construct. Scrap heat sinks yielded aluminum stock, which despite going through a bit of a machinist’s nightmare on the drill press came out surprisingly nice. Heat for the block is provided by a commercial Peltier module and controller; it looks good up to 42°, a common temperature for heat-shocking yeast and tricking them into taking up foreign DNA.

We’re impressed with how cheaply [Justin] was able to throw together these instruments, and we’re looking forward to seeing how he utilizes them. He’s already biohacked himself, so seeing what happens to yeast and bacteria in his DIY lab should be interesting.

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I Hear You Offer WiFi

We are swimming in radio transmissions from all around, and if you live above the ground floor, they are coming at you from below as well. Humans do not have a sensory organ for recognizing radio signals, but we have lots of hardware which can make sense of it. The chances are good that you are looking at one such device right now. [Frank Swain] has leaped from merely accepting the omnipresent signals from WiFi routers and portable devices to listening in on them. The audio signals are mere soundwaves, so he is not listening to every tweet and email password, merely a representation of the data’s presence. There is a sample below the break, and it sounds like a Geiger counter playing PIN•BOT.

We experience only the most minuscule sliver of information coming at us at any given moment. Machines to hack that gap are not had to find on these pages so [Frank] is in good company. Magnetosensory is a popular choice for people with a poor sense of direction. Echolocation is perfect for fans of Daredevil. Delivering new sensations could be easier than ever with high-resolution tactile displays. Detect some rather intimate data with ‘SHE BON.’

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Cat Robot’s Secret To Slim Legs? Banish The Motors!

The first thing to notice about [Bijuo]’s cat-sized quadruped robot designs (link is in Korean, Google translation here) is how slim and sleek the legs are. That’s because unlike most legged robots, the limbs themselves don’t contain any motors. Instead, the motors are in the main body, with one driving a half-circle pulley while another moves the limb as a whole. Power is transferred by a cable acting as a tendon and is offset by spring tension in the joints. The result is light, slim legs that lift and move in a remarkable gait.

[Bijuo] credits the Cheetah_Cub project as their original inspiration, and names their own variation Mini Serval, on account of the ears and in keeping with the feline nomenclature. Embedded below are two videos, the first showing leg and gait detail, and the second demonstrating the robot in motion.

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Micro-Organisms Give Up The Volts In This Biological Battery

Battery cells work by chemical reactions, and the fascinating Hybrid Microbial Fuel Cell design by [Josh Starnes] is no different. True, batteries don’t normally contain life, but the process coughs up useful electrons all the same; 1.7 V per cell in [Josh]’s design, to be precise. His proof of concept consists of eight cells in parallel, enough to give his cell phone a charge via a DC-DC boost converter. He says it’s not known how long this can be expected to last before the voltage drops to an unusable level, but it works!

Eight-cell, 3D printed proof of concept.

There are two complementary sides to each cell in [Josh]’s design. On the cathode side are phytoplankton; green micro algae that absorb carbon dioxide and sunlight. On the anode side are bacteria that break organic material (like food waste) into nitrates, and expel carbon dioxide. Version 2 of the design will incorporate a semi-permeable membrane between the cells that would allow oxygen and carbon dioxide to be exchanged while keeping the populations of micro-organisms separate; this would make the biological processes more complementary.

A battery consisting of 24 cells and a plumbing system to cycle and care for the algae and bacteria is the ultimate goal, and we hope [Josh] can get closer to that now that his project won a $1000 cash prize as one of the twenty finalists in the Power Harvesting Challenge portion of the Hackaday Prize. (Next up is the Human Computer Interface Challenge, just so you know.)

Reverse-Engineering Brains, One Neuron At A Time

Most posts here are electrical or mechanical, with a few scattered hacks from other fields. Those who also keep up with advances in biomedical research may have noticed certain areas are starting to parallel the electronics we know. [Dr. Rajib Shubert] is in one such field, and picked up on the commonality as well. He thought it’d be interesting to bridge the two worlds by explaining his research using analogies familiar to the Hackaday audience. (Video also embedded below.)

He laid the foundation with a little background, establishing that we’ve been able to see individual static neurons for a while via microscope slides and such, and we’ve been able to see activity of the whole living brain via functional MRI. These methods gradually improved our understanding of neurons, and advances within the past few years have reached an intersection of those two points: [Dr. Shubert] and colleagues now have tools to peer inside a functional brain, teasing out how it works one neuron at a time.

[Dr. Shubert]’s talk makes analogies to electronics hardware, but we can also make a software analogy treating the brain as a highly optimized (and/or obfuscated) piece of code. Virus stamping a single cell under this analogy is like isolating a single function, seeing who calls it, and who it calls. This pairs well with optogenetics techniques, which can be seen as like modifying a function to see how it affects results in real time. It certainly puts a different meaning on the phrase “working with live code”!

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